Cell Biology

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Researchers suggest new approach to build a 'nanopore' biosensor for detecting specific molecules

Researchers have spent more than three decades developing and studying miniature biosensors that can identify single molecules. In five to 10 years, when such devices may become a staple in doctors' offices, they could detect molecular markers for cancer and other diseases and assess the effectiveness of drug treatment to fight those illnesses.

28 Apr 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

The neutron reflexometry method has given scientists an atomic-level insight into the behavior of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology.

28 Apr 2021

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibres termed 'plateau potentials' that make them temporarily inactive, says a study published today in eLife.

27 Apr 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

SARS-CoV-2 suppresses the immune response in the gut

In an effort to determine the potential for COVID-19 to begin in a person's gut, and to better understand how human cells respond to SARS-CoV-2, the scientists used human intestinal cells to create organoids - 3D tissue cultures derived from human cells, which mimic the tissue or organ from which the cells originate.

27 Apr 2021

Research opens up the possibility of dietary therapy for cancer

A research group at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered molecular events that determine whether cancer cells live or die. With this knowledge, they found that reduced consumption of a specific protein building block prevents the growth of cells that become cancerous.

27 Apr 2021

Researchers map the first complete atlas of single cells that make up the human teeth

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.

27 Apr 2021

Drug cocktail can effectively activate and expand muscle stem cells

Skeletal muscle – the type of muscle that attaches to bones and enables movement – is the most abundant tissue in the human body.

27 Apr 2021

Researchers discover elusive cell type in fish sensory organs

One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells.

26 Apr 2021

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

26 Apr 2021

AI platform can identify specific proteins that allow bacteria to infect the intestines

Researchers from Tel Aviv University have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines - a method that paves the way for the creation of smart drugs that will neutralize the proteins and prevent disease, without the use of antibiotics.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

There are many different types of cancer, but they all have one thing in common: errors in the signals that control normal cell behavior can cause uncontrolled cell growth and cell division, leading to a tumor.

23 Apr 2021

Researchers develop computer model to predict the impact of individual receptors on brain activity

Researchers regard the overall distribution of receptors in the brain – the receptome – as a new approach for computer models that reproduce the function of the brain, and for diagnostics and therapy of mental disorders.

23 Apr 2021

New platform helps non-experts use AI to analyze microscopy images

A new, freely available platform helps non-experts use artificial intelligence to analyze microscopy images. The platform has been developed at Åbo Akademi University in Finland and Instituto Gulbenkian de Ciência, Portugal, and will be of big help in research and diagnostics using modern day microscopes.

23 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Recreating early embryos using stem cells

In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos.

23 Apr 2021

New imaging technique captures movies of receptors on the surface of living cells

A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children's Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.

23 Apr 2021

Cell Biology

Researchers suggest new approach to build a 'nanopore' biosensor for detecting specific molecules

Novel platform has potential to detect many disease-related biomarkers in just one test

Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Scientists identify many genes that are important in fruit flies' neuron development

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

SARS-CoV-2 suppresses the immune response in the gut

Research opens up the possibility of dietary therapy for cancer

Researchers map the first complete atlas of single cells that make up the human teeth

Drug cocktail can effectively activate and expand muscle stem cells

Researchers discover elusive cell type in fish sensory organs

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

AI platform can identify specific proteins that allow bacteria to infect the intestines

Researchers investigate how oxygen radicals protect against cancer

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

Researchers develop computer model to predict the impact of individual receptors on brain activity

New platform helps non-experts use AI to analyze microscopy images

Researchers create a cell library to study how various sugars bind to and interact with receptors

Recreating early embryos using stem cells

New imaging technique captures movies of receptors on the surface of living cells

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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