Cell Biology

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Five herbal medicines show potent activity against Babesia duncani in the lab

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data finding that five herbal medicines had potent activity compared to commonly-used antibiotics in test tubes against Babesia duncani, a malaria-like parasite found on the West Coast of the U.S. that causes the disease babesiosis.

9 Mar 2021

Cooperation between two key genes drives breast cancer growth

Cooperation is generally a good thing -- working together to reach a goal. But in the case of cancer, it can be detrimental. University of Cincinnati researchers have discovered that cooperation between two key genes drives cancer growth, spread and treatment resistance in one particularly aggressive type of breast cancer.

9 Mar 2021

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Some of Princeton's leading cancer researchers were startled to discover that what they thought was a straightforward investigation into how cancer spreads through the body -- metastasis -- turned up evidence of liquid-liquid phase separations: the new field of biology research that investigates how liquid blobs of living materials merge into each other, similar to the movements seen in a lava lamp or in liquid mercury.

9 Mar 2021

Study describes the infection of human cells by intestinal pathogen during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

9 Mar 2021

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

At the virtual 17th US HUPO Conference (US HUPO 2021), Bruker Corporation (Nasdaq: BRKR) today announces progress with several collaborations in deep, unbiased plasma proteomics, leveraging the speed, sensitivity and dynamic range of 4D proteomics on timsTOF Pro systems.

From Bruker Life Sciences Mass Spectrometry 9 Mar 2021

Compounds in green and black tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

8 Mar 2021

Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

8 Mar 2021

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of lymphocytes, and a large proportion of patients are either unresponsive or develop resistance towards R-CHOP—the standard treatment regimen.

8 Mar 2021

Study reveals physical phenomena relied by oocytes to grow big

Egg cells are by far the largest cells produced by most organisms. In humans, they are several times larger than a typical body cell and about 10,000 times larger than sperm cells.

8 Mar 2021

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria.

5 Mar 2021

Study suggests revisiting 14-day limit on human embryo in a dish

An international team of bioethicists and scientists, led by a researcher at Case Western Reserve University, contends it may be justified to go beyond the standing 14-day limit that restricts how long researchers can study human embryos in a dish.

5 Mar 2021

SARS-CoV-2 can evade immune response by T-killer cells through mutations

The body's immune response plays a crucial role in the course of a SARS-CoV-2 infection. In addition to antibodies, the so-called T-killer cells, are also responsible for detecting viruses in the body and eliminating them.

5 Mar 2021

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pancreatitis drug Camostat inhibits new SARS-CoV-2 activators identified in the upper respiratory tract. There are no therapeutics available that have been developed for COVID-19 treatment.

5 Mar 2021

Researchers decipher how interspecies interactions arise, evolve and are maintained

Interspecies interactions are the foundation of ecosystems, from soil to ocean to the human gut. Among the many different types of interactions, syntrophy is a particularly important and mutually beneficial interspecies interaction where one partner provides a chemical or nutrient that is consumed by the other in exchange for a reward.

5 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

4 Mar 2021

Cell Biology

Five herbal medicines show potent activity against Babesia duncani in the lab

Cooperation between two key genes drives breast cancer growth

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Study describes the infection of human cells by intestinal pathogen during spaceflight

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

Compounds in green and black tea relax blood vessels by activating ion channel proteins

Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Study reveals physical phenomena relied by oocytes to grow big

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Study suggests revisiting 14-day limit on human embryo in a dish

SARS-CoV-2 can evade immune response by T-killer cells through mutations

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Researchers decipher how interspecies interactions arise, evolve and are maintained

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

New transcriptome‐based aging clock reads the biological age of an organism

Researchers identify drug target to fight Parkinson’s and Alzheimer’s disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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