Cell Biology

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Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Gaurav Gaiha, MD, DPhil, a member of the Ragon Institute of MGH, MIT and Harvard, studies HIV, one of the fastest-mutating viruses known to humankind.

2 Jul 2021

Research points towards macropinocytosis as a target for future cancer treatment

It is the membrane of cancer cells that is at the focus of the new research now showing a completely new way in which cancer cells can repair the damage that can otherwise kill them.

2 Jul 2021

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

In cancer research, it's a common goal to find something about cancer cells -- some sort of molecule -- that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. Even better: The molecule isn't present in healthy cells, so they remain untouched by the new therapy.

2 Jul 2021

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

A year after University at Buffalo scientists demonstrated that it was possible to produce millions of mature human cells in a mouse embryo, they have published a detailed description of the method so that other laboratories can do it, too.

2 Jul 2021

New lab system uses grass blades to turn cells into cultured meat

An affordable lab system that uses grass blades to turn cells into cultured meat has been developed at the University of Bath in the UK.

2 Jul 2021

High levels of neutrophil extracellular traps found in airways of severely ill Covid-19 patients

When researchers at Lund University in Sweden performed advanced analyses of sputum from the airways of severely ill Covid-19 patients, they found high levels of neutrophil extracellular traps (NETs).

1 Jul 2021

Study highlights the importance of T cell cross reactivity in stopping severe COVID-19 infections

Researchers at La Jolla Institute for Immunology have found that T cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-CoV-2 variants.

1 Jul 2021

Scientists uncover features of T cells that distinguish fatal COVID-19 from non-fatal cases

While vaccines are doing a remarkable job of slowing the COVID-19 pandemic, infected people can still die from severe illness and new medications to treat them have been slow to arise.

1 Jul 2021

Novel optical device could open new avenues in advanced microscopy

What if a microscope allowed us to explore the 3D microcosm of blood vessels, nerves, and cancer cells instantaneously in virtual reality? What if it could provide views from multiple directions in real time without physically moving the specimen and worked up to 100 times faster than current technology?

1 Jul 2021

Researchers develop the world's first digital cancer cell model

The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research.

1 Jul 2021

AMSBIO offers an extensive collection of normal and disease state FFPE tissue blocks

AMSBIO has established an unmatched commercial biorepository and procurement network that includes a large selection of fully characterized and annotated Formalin-Fixed Paraffin-Embedded tissue blocks to help streamline your research.

From AMS Biotechnology 1 Jul 2021

New study maps evolutionary history and interrelationships of protein domains

Proteins have been quietly taking over our lives since the COVID-19 pandemic began. We've been living at the whim of the virus's so-called "spike" protein, which has mutated dozens of times to create increasingly deadly variants. But the truth is, we have always been ruled by proteins. At the cellular level, they're responsible for pretty much everything.

1 Jul 2021

Breakthrough method for tracking mRNA molecules with fluorescence

Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope - without affecting their properties or subsequent activity.

30 Jun 2021

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis.

30 Jun 2021

New method to transport RNA-based drugs to subpopulation of immune cells

Tel Aviv University's groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions. In the framework of this study, the researchers were able to create a new method of transporting RNA-based drugs to a subpopulation of immune cells involved in the inflammation process, and target the disease-inflamed cell without causing damage to other cells.

30 Jun 2021

Researchers show how Covid-19 changes the size and stiffness of red and white blood cells

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: Covid-19 significantly changes the size and stiffness of red and white blood cells - sometimes over months.

29 Jun 2021

Scientists mimic the natural development of mammal using stem cells

The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: It was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created.

29 Jun 2021

Cell Biology

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Research points towards macropinocytosis as a target for future cancer treatment

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

New lab system uses grass blades to turn cells into cultured meat

High levels of neutrophil extracellular traps found in airways of severely ill Covid-19 patients

Study highlights the importance of T cell cross reactivity in stopping severe COVID-19 infections

Scientists uncover features of T cells that distinguish fatal COVID-19 from non-fatal cases

Novel optical device could open new avenues in advanced microscopy

Researchers develop the world's first digital cancer cell model

AMSBIO offers an extensive collection of normal and disease state FFPE tissue blocks

New study maps evolutionary history and interrelationships of protein domains

Breakthrough method for tracking mRNA molecules with fluorescence

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

New method to transport RNA-based drugs to subpopulation of immune cells

Researchers show how Covid-19 changes the size and stiffness of red and white blood cells

Scientists mimic the natural development of mammal using stem cells

H69/V70 deletion in Alpha variant enables SARS-CoV-2 to overcome chinks in its armor

Specific lung cell exhibits immune properties and improves respiratory viral disease outcomes

Maternal Omega 3-rich diet may reduce onset of breast cancer in offspring

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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