Cell Biology

RSS

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Recent research has found that changes in the gut microbiota - the trillions of bacteria and other microbes that live in the intestines - can alter the brain and behavior. Now, a study led by scientists at UCLA could elucidate how and why that phenomenon occurs.

17 Aug 2021

Age and sex affect the outcomes of time-restricted eating

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.

17 Aug 2021

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.

17 Aug 2021

Blue light can activate key signaling pathway that plays role in embryonic development and cancer

Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis.

17 Aug 2021

Protein implicated in tumor growth may protect against neurodegenerative diseases

Cells translate their genetic material at rapid rates with exquisite precision to reproduce, repair damage or even combat disease.

17 Aug 2021

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

17 Aug 2021

Biotium releases new ExoBrite EV Membrane Staining Kits

Biotium, a leading supplier and inventor of fluorescent cellular probes for life science research, announces the release of new ExoBrite™ EV Membrane Staining Kits.

17 Aug 2021

Treatment with stem cell grafts promotes tendon healing in sheep

Tendon injuries in sheep that were treated with stem cell grafts achieved, in just two months, a diameter and hardness similar to the original healthy tendon, according to the results of a study released in STEM CELLS Translational Medicine.

16 Aug 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Too many "exhausted" T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

Simple roundworm may hold the key to understanding cell death processes

A biologist at The University of Texas at Arlington hopes that a simple roundworm might hold the key to understanding novel cell death processes. Such knowledge could lead to improved therapies to treat a variety of conditions in humans, including cancer and neurological injuries.

14 Aug 2021

Enzyme acts as a sensor to find the hiding spots of viruses

While some types of RNA viruses cloak themselves to hide inside a cell and create copies of themselves, a "detective enzyme" might be attuned to their whereabouts. A slight variation in their genomic code gives some people's cells the capacity to produce this sensor.

14 Aug 2021

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A - a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection - is controlled.

13 Aug 2021

Cell Biology

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

New assay using fresh uncultured lung tumor cells could guide personalized treatments

New bioengineered lung model could help scientists to advance research in lung conditions

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Age and sex affect the outcomes of time-restricted eating

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Blue light can activate key signaling pathway that plays role in embryonic development and cancer

Protein implicated in tumor growth may protect against neurodegenerative diseases

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

Biotium releases new ExoBrite EV Membrane Staining Kits

Treatment with stem cell grafts promotes tendon healing in sheep

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Simple roundworm may hold the key to understanding cell death processes

Enzyme acts as a sensor to find the hiding spots of viruses

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

Structure of BRCA2 protein complex critical for DNA repair solved

Biomedical scientists need to do more to improve the relevance, reproducibility of cell culture research

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Latest Life Science News