Cell Biology

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Researchers determine the structure of nanomachine essential for functioning of mTOR

The principle that form follows function does not only apply to design and architecture. It also applies to biology

8 Jul 2021

New biological pathway selectively controls how key immune cells mature into functional components

Immunologists at St. Jude Children's Research Hospital have identified a biological pathway that selectively controls how key immune cells, called T follicular helper cells, mature into functional components of the immune system.

8 Jul 2021

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, as they describe in two proof-of-concept studies published in the American Journal of Human Genetics.

8 Jul 2021

Uncovering cellular mechanism related to gene silencing therapies

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

7 Jul 2021

NYUAD researchers unlock an epigenetic code that allows liver regeneration

NYU Abu Dhabi researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate.

6 Jul 2021

Scientists unravel how cell death is initiated on a molecular level

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors.

6 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Scientists discover pathway that sheds new light on brain damage-induced cell division

Most human cells are able to repair damage by dividing at wounds.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.

6 Jul 2021

New method expands view into activity of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

6 Jul 2021

Research reveals the role of dopamine in how songbirds learn complex new sounds

Neuroscientists at the University of Massachusetts Amherst have demonstrated in new research that dopamine plays a key role in how songbirds learn complex new sounds.

5 Jul 2021

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Gaurav Gaiha, MD, DPhil, a member of the Ragon Institute of MGH, MIT and Harvard, studies HIV, one of the fastest-mutating viruses known to humankind.

2 Jul 2021

Research points towards macropinocytosis as a target for future cancer treatment

It is the membrane of cancer cells that is at the focus of the new research now showing a completely new way in which cancer cells can repair the damage that can otherwise kill them.

2 Jul 2021

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

In cancer research, it's a common goal to find something about cancer cells -- some sort of molecule -- that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. Even better: The molecule isn't present in healthy cells, so they remain untouched by the new therapy.

2 Jul 2021

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

A year after University at Buffalo scientists demonstrated that it was possible to produce millions of mature human cells in a mouse embryo, they have published a detailed description of the method so that other laboratories can do it, too.

2 Jul 2021

New lab system uses grass blades to turn cells into cultured meat

An affordable lab system that uses grass blades to turn cells into cultured meat has been developed at the University of Bath in the UK.

2 Jul 2021

Cell Biology

Researchers determine the structure of nanomachine essential for functioning of mTOR

New biological pathway selectively controls how key immune cells mature into functional components

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Uncovering cellular mechanism related to gene silencing therapies

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Study unravels the link between chromosomal instability and cellular senescence

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Scientists unravel how cell death is initiated on a molecular level

A new method for generating metabolic profiles of single cells

Scientists discover pathway that sheds new light on brain damage-induced cell division

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

New method expands view into activity of single cells

Research reveals the role of dopamine in how songbirds learn complex new sounds

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Research points towards macropinocytosis as a target for future cancer treatment

RNA-binding proteins represent a new class of drug targets for triple-negative breast cancer

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

New lab system uses grass blades to turn cells into cultured meat

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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