Cell Biology

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Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

Quantum physics helps trigger cancer cell death

Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles.

14 Jul 2021

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Eggs and embryos go through a more dynamic and complex journey than previously thought

The journey of the egg and the embryo through the fallopian tube or oviduct toward the uterus is not well understood, mainly because it is inaccessible for direct imaging.

14 Jul 2021

Research provides an update on how electrical impulses in the heart travel from cell to cell

The rhythm in a working heart is regulated by electrical impulses. Disturbances of this bioelectrical process can result in cardiac arrhythmias, or irregularities in heartbeat -- a common ailment that can lead to illness and death.

13 Jul 2021

Mechanical factors play a key role in the natural growth of human organs

In addition to chemical factors, mechanical influences play an important role in the natural growth of human organs such as kidneys, lungs and mammary glands - but also in the development of tumors.

13 Jul 2021

Understanding the molecular mechanisms behind lung cancer relapse

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away.

13 Jul 2021

Researchers discover new set of signals that control production of goblet cells in the lung

Proper lung function relies on the precise balance of specialized epithelial cells (cells that line the surfaces of the body) that coordinate functions to maintain homeostasis.

13 Jul 2021

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients.

12 Jul 2021

Modular network organization critical for persistent neural activity and brain communication

Recall a phone number or directions just recited and your brain will be actively communicating across many regions. It is thought that working memory relies on interactions between these regions, but how these brain areas interact and properly represent memory has remained a mystery.

12 Jul 2021

New insights can guide precise personalized hepatocellular carcinoma medicine

A research group led by Prof. PIAO Hailong from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) identified hepatocellular carcinoma (HCC) subtypes with distinctive metabolic phenotypes through bioinformatics and machine learning methods, and elucidated the potential mechanisms based on a metabolite-protein interaction network and multi-omics data.

12 Jul 2021

Researchers gain new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Immaturity of gut microbiota and epithelial barriers linked to neonatal meningitis

Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population.

9 Jul 2021

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

The Delta variant was detected for the first time in India in October 2020 and has since spread throughout the world.

9 Jul 2021

Scientists unravel mechanisms involved in epithelial integrity

To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity.

9 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy.

9 Jul 2021

Research reveals how mitochondria keep their reactive oxygen species production in check

Mitochondria, the powerhouse of the cell, convert sustenance into energy, fueling the cell's activities. In addition to power, mitochondria also produce reactive oxygen species, byproduct molecules primed to help facilitate communication among the other units in the cells.

9 Jul 2021

Novel tool enables multi-resolution characterization of molecular taxonomies

The discovery of novel groups or categories within diseases, organisms and biological processes and their organization into hierarchical relationships are important and recurrent pursuits in biology and medicine, which may help elucidate group-specific vulnerabilities and ultimately novel therapeutic interventions.

8 Jul 2021

Study uncovers the complex cellular mechanisms of Ebola virus

Mount Sinai researchers have uncovered the complex cellular mechanisms of the Ebola virus, which could help explain its severe toll on humans and identify potential pathways to treatment and prevention.

8 Jul 2021

Cell Biology

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Quantum physics helps trigger cancer cell death

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Eggs and embryos go through a more dynamic and complex journey than previously thought

Research provides an update on how electrical impulses in the heart travel from cell to cell

Mechanical factors play a key role in the natural growth of human organs

Understanding the molecular mechanisms behind lung cancer relapse

Researchers discover new set of signals that control production of goblet cells in the lung

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Modular network organization critical for persistent neural activity and brain communication

New insights can guide precise personalized hepatocellular carcinoma medicine

Researchers gain new insights into the pathology of Usher syndrome

Immaturity of gut microbiota and epithelial barriers linked to neonatal meningitis

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

Scientists unravel mechanisms involved in epithelial integrity

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

Research reveals how mitochondria keep their reactive oxygen species production in check

Novel tool enables multi-resolution characterization of molecular taxonomies

Study uncovers the complex cellular mechanisms of Ebola virus

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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