Cell Biology

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Scientists identify new therapeutic target for several aggressive cancers

A protein in tumor cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown.

4 Aug 2021

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells.

4 Aug 2021

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Genetic testing and selection of embryos generated from in vitro fertilization have given rise to the controversial “designer baby” debate.

4 Aug 2021

Surplus sugar may cause our cellular powerplants to become less efficient, finds study

The average American eats roughly 22 teaspoons of added sugar a day - more than three times the recommended amount for women and more than double the recommended amount for men.

3 Aug 2021

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

In a new study, researchers at the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact used start codon disruption with CRISPR-Cas9 gene editing to prevent Fuchs' corneal dystrophy in mice.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

Lipid blast shield protects natural killer cells and also some cancer cells

A newly discovered fat 'shield' that prevents natural killer cells from being destroyed by their own deadly biological weapons also allows some cancer cells to evade an immune system attack, a study at Columbia University has found.

3 Aug 2021

Researchers discover brain's switching system used in information processing and storing of memories

A team of scientists has uncovered a system in the brain used in the processing of information and in the storing of memories--akin to how railroad switches control a train's destination. The findings offer new insights into how the brain functions.

3 Aug 2021

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Treating mice that have a Parkinson's disease-causing mutation with a small molecule compound restores the removal of damaged mitochondria from their brain cells, shows a study published today in eLife.

3 Aug 2021

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry.

3 Aug 2021

Experimental model shows how topological defects in the mesothelium affect ovarian cancer metastasis

Ovarian cancer devastates more than 20,000 women in the U.S. every year, due in part to its tendency to evade detection and present after metastatic spread. A key element to slowing metastasis is understanding the mechanisms of how tumor cells invade tissues.

3 Aug 2021

Novel type of cellular therapy safe for knee pain caused by osteoarthritis, study confirms

A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis.

3 Aug 2021

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

A new discovery explains what determines the number and position of genetic exchanges that occur in sex cells, such as pollen and eggs in plants, or sperm and eggs in humans.

3 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight - not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today in Science Advances.

30 Jul 2021

Researchers develop two complementary bladder models to study UTIs

Urinary tract infections (UTIs) are among the most common bacterial infections. They usually require treatment with antibiotics, and almost a quarter of treated cases lead to recurrent infection.

30 Jul 2021

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Mitofusin 2 is a key protein in the regulation of the physiology of mitochondria ─cellular organelles that produce energy─ involved in several neurodegenerative and cardiovascular diseases, as well as in cancer.

30 Jul 2021

New study shines light on how plant cells perceive and respond to mechanical forces

Minuscule tunnels through the cell membrane help cells to perceive and respond to mechanical forces, such as pressure or touch. A new study in the journal Science is among the first to directly investigate what one type of these mechanosensitive ion channels is doing in the tip-growing cells in moss and pollen tubes of flowering plants, and how.

29 Jul 2021

Study examines the role of programmed cell death ligands in skin immune responses

T cells are a crucial part of the human adaptive immune system. In response to a foreign invader in the body, various subsets of T cells are responsible for several functions that include killing infected cells and secreting signaling molecules called cytokines that tell other immune cells where to go and what to do.

29 Jul 2021

Antibacterial immunity may change in the intestines based on circadian cycle

The body's ability to prevent food poisoning by producing a natural antimicrobial compound increases during the day, when exposure to noxious bacteria is most likely, a new study by UT Southwestern scientists suggests.

28 Jul 2021

Cell Biology

Scientists identify new therapeutic target for several aggressive cancers

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Surplus sugar may cause our cellular powerplants to become less efficient, finds study

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Lipid blast shield protects natural killer cells and also some cancer cells

Researchers discover brain's switching system used in information processing and storing of memories

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

Experimental model shows how topological defects in the mesothelium affect ovarian cancer metastasis

Novel type of cellular therapy safe for knee pain caused by osteoarthritis, study confirms

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

Researchers develop two complementary bladder models to study UTIs

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

New study shines light on how plant cells perceive and respond to mechanical forces

Study examines the role of programmed cell death ligands in skin immune responses

Antibacterial immunity may change in the intestines based on circadian cycle

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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