Cell Biology

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Scientists devise new method to map HIV's sugary shield in unprecedented detail

Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system.

23 Oct 2020

Study reveals new and essential details of how photoreceptors work

Moving around in the half-light is difficult but not impossible. To help us in this undertaking we have the rods, a type of light-sensitive cells (photoreceptors) present in the retina of vertebrates, capable of detecting very low lights which allow to move about even in poorly lit cellars or caves.

23 Oct 2020

Neutrophils have more functions in the body than previously thought

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought.

23 Oct 2020

Researchers find a new therapeutic approach to combat leukemia

Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, have found a new way to make these cells vulnerable by specifically dislodging these cells from their niches.

23 Oct 2020

Oregon biologists reveal molecular mechanisms that produce DNA damage in sperm

University of Oregon biologists have used the model organism Caenorhabditis elegans to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to heat.

23 Oct 2020

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

Bruker Corporation today announced the release of the Vutara VXL Super-Resolution Fluorescence Microscope for nanoscale biological imaging. The new system opens an affordable and easy-to-use path for both core facilities and individual investigators to enter the world of super-resolution imaging by incorporating Bruker’s industry-leading single-molecule localization (SML) technology in a streamlined system with compact footprint.

From Bruker Nano Surfaces and Metrology 23 Oct 2020

Researchers develop a novel way to simplify cellular optogenetic tools

Cellular optogenetics is a technique that allows researchers to use light to precisely control cell signaling and function in space and time enabling the investigation of mechanisms involved in disease processes.

22 Oct 2020

Research findings could potentially help exploit the weaknesses of cancer cells

Every cell in our body constantly divides to form new cells. This happens without us even thinking about it. However, every single time a cell divides, a complicated process has to unfold just the right way for our cells to avoid sickness and death.

22 Oct 2020

'Mini-lungs' can provide important insights into how COVID-19 damages the lungs

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

22 Oct 2020

Study shows how genetic predisposition contributes to the development of multiple sclerosis

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors.

22 Oct 2020

Study unravels consequences of mating at the molecular level

While it is known that stem cells have the ability to develop into all tissues in a precisely regulated process, the way environmental cues affect stem cell behavior has remained poorly understood.

21 Oct 2020

Research elucidates molecular mechanism behind learning and memory function

The long-term potentiation (LTP) and long-term depression (LTD) of the strength of hippocampal excitatory synapse involved in learning and memory formation in brain have been separately explained, but the molecular mechanism that comprehensively explains them has not been elucidated.

21 Oct 2020

Study characterizes biochemical mechanism of cancer-linked enzyme

A new study led by scientists at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that increases the activity of a molecule whose presence is observed in many types of cancer.

21 Oct 2020

New study could help achieve multicolor imaging with fluorescent biosensors cells

With a little tweak of the color palette, University of Virginia School of Medicine researchers have made it easier for scientists to understand biological processes, track happenings inside individual cells, unravel the mysteries of disease and develop new treatments.

21 Oct 2020

Minuscule tracking devices show how living cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

20 Oct 2020

3D whole-heart imaging technique provides new insights on congenital heart disease

A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease.

20 Oct 2020

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Scientists uncover important disease-fighting role for cells in the liver

Scientists at Scripps Research have uncovered an important disease-fighting role for cells called hepatocytes, which constitute most of the liver. The discovery could potentially be harnessed to develop new medicines for viral illnesses.

19 Oct 2020

Cell nucleus may play role in enabling cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

19 Oct 2020

New AI-based method of image analysis finds new cell types in tissue

In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala University researchers have now developed an entirely new method of image analysis.

19 Oct 2020