Cell Biology

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Human immune repertoire may not commonly produce cross-neutralizing antibodies to coronaviruses

Patients infected with either severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 produce antibodies that bind to the other coronavirus, but the cross-reactive antibodies are not cross protective, at least in cell-culture experiments, researchers report May 17 in the journal Cell Reports.

18 May 2020

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Hyaline Fibromatosis Syndrome (HFS) is a rare but severe genetic disease that affects babies, children, and adults. Hyaline, a glassy substance, accumulates in the skin and various organs, and causes painful deformities that can lead to an early death.

18 May 2020

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK).

18 May 2020

A new tool to study and map the intricacies of intercellular signaling

How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing a cancerous tumor to metastasize and become much more difficult to treat effectively?

18 May 2020

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

New research from CSHL scientists suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells.

18 May 2020

Mouse model helps track organism’s development from embryonic stage to adulthood

Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood.

15 May 2020

New study sheds light on the cause of stem cell mutations

Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.

15 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

The researcher Manel Esteller performs the first massive epigenetic characterization in organoids or 3D cancer cultures and makes the data available to the research community to facilitate new findings on tumor development and progression.

15 May 2020

Scientists describe new mechanism of cellular locomotion

Whilst the whole world is in lockdown during the current Corona crisis, certain cells within our bodies are still travelling long-distance: while this happens when you develop pneumonia, any ordinary cut on your finger will also trigger white blood cells--aka leukocytes--to instantly move out of your blood vessels into the site of inflammation.

14 May 2020

Study uncovers how the body synthesizes triglycerides

Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease.

13 May 2020

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.

13 May 2020

Researchers make a significant leap in mucus biology

Worldwide, hundreds of millions of people are impacted by chronic respiratory disease. COPD alone affects more than 250 million people, causing 3 million deaths each year.

13 May 2020

Adult skates go one step further than cartilage growth, can repair injured cartilage

Nearly a quarter of Americans suffer from arthritis, most commonly due to the wear and tear of the cartilage that protects the joints.

12 May 2020

Scientists uncover important functions of a special protein during cell division

In a new study, researchers from the University of Copenhagen have discovered two important functions of a protein called RTEL1 during cell division.

12 May 2020

New tool could help physicians diagnose the cause of blood clots

A new tool using cutting-edge technology is able to distinguish different types of blood clots based on what caused them, according to a study published in eLife.

12 May 2020

Leica Microsystems Donate an Advanced Microscopy System to Charité’s Institute of Virology to Progress Covid-19 Research

Since the start of the current coronavirus outbreak, the Institute of Virology on Campus Charité Mitte, led by Director Prof. Dr. Christian Drosten, has been at the forefront of viral research into SARS-CoV-2, the virus that causes Covid-19.

From Leica Microsystems GmbH 12 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Microbiome controls the fitness of our immune system

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

11 May 2020

Cell Biology

Human immune repertoire may not commonly produce cross-neutralizing antibodies to coronaviruses

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

A new tool to study and map the intricacies of intercellular signaling

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

Mouse model helps track organism’s development from embryonic stage to adulthood

New study sheds light on the cause of stem cell mutations

First detailed study of the epigenetic landscape of human tumor organoids

Scientists describe new mechanism of cellular locomotion

Study uncovers how the body synthesizes triglycerides

A deep look into hormone-producing cells of the gut

First detailed study of the epigenetic landscape of human tumor organoids

Harnessing the formation of natural killer–tumor cell immunological synapse to treat solid cancers

Researchers make a significant leap in mucus biology

Adult skates go one step further than cartilage growth, can repair injured cartilage

Scientists uncover important functions of a special protein during cell division

New tool could help physicians diagnose the cause of blood clots

Leica Microsystems Donate an Advanced Microscopy System to Charité’s Institute of Virology to Progress Covid-19 Research

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

Microbiome controls the fitness of our immune system

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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