Cell Biology

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A novel approach to intraplaque mast cell characterization in atherosclerosis

Researchers have devised a new flow-cytometric method to identify a subpopulation of intraplaque mast cells, the primary immune mediators of atherosclerosis.

6 Jun 2019

Scientists successfully carry out gene editing in vivo

Scientists at Harvard University have successfully proven that stem cells can be edited inside the body, rather than in a petri dish.

5 Jun 2019

Study uncovers pigment cells that change their identity during normal development

A new study by researchers at the University of Virginia and other institutions has discovered a type of pigment cell in zebrafish that can transform after development into another cell type.

4 Jun 2019

Gene variant evolved to cope with modern high-carb diets

The gene variant became more common in humans after cooking and farming became widespread, and might now help people avoid diabetes, according to the findings published in eLife.

4 Jun 2019

Scientists highlight advances and uses of organoids in gastroenterology and hepatology

One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo.

4 Jun 2019

New tool reveals how genes interact to form tissues and organisms

Although the knowledge we have about human cells and tissues has steadily increased over recent decades, many things remain unknown.

4 Jun 2019

Study identifies promising cancer target for liposarcoma

A study conducted by a team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed a close association between liposarcoma (LPS), a type of cancer that develops from fat cells, and the bromodomain and extraterminal (BET) protein family.

3 Jun 2019

Researchers determine 3D structure of proteins inside living eukaryotic cells

Researchers from Tokyo Metropolitan University have successfully determined the high-resolution three-dimensional structure of proteins inside living eukaryotic cells.

3 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

Tumor-fighting combination targets aggressive form of brain cancer

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

31 May 2019

Study uncovers how simpler organisms manage recycling of incomplete proteins

Our cells' process for transforming genes into useful proteins works much like an automobile factory's assembly line; there are schematics, parts, workers, motors, quality control systems and even recycling crews.

31 May 2019

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

A method of growing blood stem cells in the laboratory has been developed by researchers at Stanford University and the University of Tokyo, in a breakthrough that could spare some people with blood and immune disorders from the side effects of intensive chemotherapy and radiotherapy.

31 May 2019

African rodents immune to pain caused by wasabi

A new report in Science provides the first evidence of a mammal - the highveld mole-rat - being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of wasabi.

31 May 2019

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

A team of researchers led by Kazuhiro Suzuki from the Immunology Frontier Research Center at Osaka University discovered the COMMD3/8 complex as a molecule involved in immune cell migration, clarifying that the complex plays a critical role in the establishment of immune responses.

31 May 2019

New studies from UCI shine light on circadian clocks

Can your liver sense when you're staring at a television screen or cellphone late at night? Apparently so, and when such activity is detected, the organ can throw your circadian rhythms out of whack, leaving you more susceptible to health problems.

30 May 2019

Researchers find new molecular targets for fighting autoimmunity

BRCA--the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system.

30 May 2019

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1.

29 May 2019

Scientists unmask stem cell identity using gene-sequencing technology

Scientists from The University of Queensland's Diamantina Institute have revealed the difference between a stem cell and other blood vessel cells using gene-sequencing technology.

29 May 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

New fluorescent probe specifically labels microglia cells

Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents.

29 May 2019