Cell Biology

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McMaster researchers map toxic protein associated with Alzheimer's

A team of researchers from McMaster University has mapped at atomic resolution a toxic protein linked to Alzheimer's disease, allowing them to better understand what is happening deep within the brain during the earliest stages of the disease.

20 Jun 2019

New probe can identify and latch onto proteins on surface of endoplasmic reticulum

Sigma receptors are proteins found on mainly the surface of endoplasmic reticulum in certain cells. Sigma-1 and sigma-2 are the two main classes of these receptors.

20 Jun 2019

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Researchers have developed three novel FACS protocols that can be used to isolate neural progenitors, astrocytes, and neurons from infected cerebral organoids.

19 Jun 2019

FACS-based CRISPR screening shows how Chlamydia bacterium invades host cells

Using FACS-based CRISPR screening, scientists have identified three candidate genes that may facilitate the invasion of Chlamydia trachomatis into host cells.

19 Jun 2019

Novel microfluidic device captures and isolates circulating tumor cell clusters

Cancer touches nearly everyone in one way or another, and regrettably, it will claim another 600,000 lives in the U.S. in 2019, according to the American Cancer Society. Researchers from San Diego State University, TumorGen MDx Inc., and Sanford Burnham Prebys Medical Discovery Institute set out to explore a seemingly basic question: What is it about cancer that kills?

19 Jun 2019

Study links high number of copies of chromosomal region to chemotherapeutic drug resistance

Researchers at the Bellvitge Biomedical Research Institute, with the participation of collaborators from the Baylor College of Medicine and the University Institute of Oncology of Asturias, publish today in Cancer Research a study where they relate the high number of copies of a chromosomal region with the appearance of resistance to a chemotherapeutic drug.

19 Jun 2019

The basal forebrain may hold clues to food avoidance behavior

After fasting for 24 hours the typical laboratory mouse spends much time eating. Surprisingly, this is not what Jay M. Patel saw when he was studying basal forebrain circuits in mice.

18 Jun 2019

Researchers discover redundancies in immune cells

Researchers at ETH Zurich have discovered redundancies in the biochemical signaling pathways of immune cells. This finding has important implications for advances in cancer immunotherapy, among other areas.

18 Jun 2019

Complement system shown to remove dead cells in retinitis pigmentosa, contradicting previous research

Researchers have found that the complement system seems to protect against retinal degeneration in retinitis pigmentosa.

18 Jun 2019

Novel lung map reveals new cells responsible for asthma

Researchers working on the Human Cell Atlas initiative have produced a detailed map of the human lungs that could lead to new treatments for asthma.

18 Jun 2019

Scientists delay aging using protein found in young mice

Scientists have shown that a protein which is abundant in the blood of young mice can delay the aging process of older mice.

17 Jun 2019

Researchers examine transport mechanism of bacterial membrane protein

An international research team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.

17 Jun 2019

Researchers develop new 3D tissue imaging technique to study disease at cellular level

To diagnose and treat diseases like cancer, scientists and doctors must understand how cells respond to different medical conditions and treatments.

14 Jun 2019

Researchers uncover new mechanism by which cells communicate in inflammatory processes

A research group from MedUni Vienna and CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences has discovered a new mechanism by which cells communicate in inflammatory processes.

14 Jun 2019

Ultra-Small Microelectrode Biosensors for Brain Injury Analysis

An interview with Stéphane Marinesco, discussing the development of ultra-small microelectrode biosensors for the analysis of traumatic brain injuries.

From Pittcon 14 Jun 2019

Super-Resolution Raman Imaging with Plasmonic Substrates

Renee Frontiera discusses the development of a super-resolution Raman microscope that could one day supersede fluorescence-based super-resolution microscopes.

From Pittcon 14 Jun 2019

New method allows cells to be produced in shorter time and with greater success

A recent study published in the April 8 issue of Nature Chemical Biology improves on the "Cellular Reprogramming" method developed by Nobel Laureate in Medicine and Physiology Prof. Shinya Yamanaka, making it possible to produce cells in a considerably shorter time and with greater success. Yamanaka's method, which is referred to as "Cellular Reprogramming", obtains pluripotent cells, similar to the ones we know exist in the very early stages of the embryo

14 Jun 2019