Cell Biology

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Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018

'Digital brain' recreates protein trafficking in the brain

Researchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.

12 Oct 2018

Scientists use haploid stem cells to produce mice with same-sex parents

In a new study, Chinese researchers were able to produce healthy mouse pups with two mothers. The research involved the use of haploid embryonic stem cells.

12 Oct 2018

Basophils play key role in development of macrophages in the lung

The adult lung consists of different, highly specialized cell types that are protected by a variety of immune cells.

12 Oct 2018

Scientists reprogram mature inhibitory neurons into dopaminergic cells

Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells.

12 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Low levels of cellular copper may make fat cells fatter

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11 Oct 2018

Researchers develop organoid that functions as real salivary gland

Researchers have successfully used induced pluripotent stem cells to grow a 3D salivary gland tissue that produces saliva when implanted in mice.

11 Oct 2018

Scientists succeed in growing functional salivary gland

A research group led by scientists from Showa University and the RIKEN Center for Biosystems Dynamics Research in Japan have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

11 Oct 2018

Scientists uncover how proteins meet on the cell membrane

Scripps Research scientists have uncovered the workings of a critical process in cell survival. Their study, published recently in the Proceedings of the National Academy of Sciences, is the first to show exactly how a protein called talin activates another critical protein, called integrin, to do its job on the cell membrane.

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Brown researchers uncover new clues about ALS progression

Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing.

10 Oct 2018

Micropeptide molecule could be promising gene therapy target to treat heart failure

Researchers have discovered a micropeptide molecule that can restore normal heart function in mice, according to a study in eLife.

10 Oct 2018

Antibody Screening Tools; Improving Workflows

Antibody screening tools have exponentially increased the rate that candidates can be screened, multiplexing will increase processing to thousands per hour.¬

From Sartorius 9 Oct 2018

Researchers create open access database on healthy immunity

Researchers have created a freely available database of healthy human immunity that can serve as an instant comparison group in immune system studies.

9 Oct 2018

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

DFG publishes new position paper on synthetic biology

Scientific developments in the field of synthetic biology have often given rise to public debate on the possible need for additional regulation. In response, the Permanent Senate Commission on Genetic Research of the Deutsche Forschungsgemeinschaft has published a position paper on synthetic biology, in which it describes key scientific advancements in the field within the context of current public discourse.

8 Oct 2018

Scientists call for microbiota vault of healthy bacteria

A team of researchers are gathering bacteria from across the world to create a microbiota vault containing healthy bacteria from the human gut and skin.

5 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

Amputation injury is reflected in bioelectric properties of opposing, undamaged limb

In research that extends knowledge about the physiology of regeneration and wound repair, Tufts University biologists have discovered that amputation of one limb is immediately reflected in the bioelectric properties of the contralateral, or opposing, undamaged limb of developing frogs.

5 Oct 2018