Cell Biology

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Researchers develop new system for efficiently producing human norovirus

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells to develop into a type of cell that usually lines the intestine, they created a cellular environment that can be used for producing the virus, studying how it interacts with human cells, and investigating potential vaccines.

11 Dec 2018

Study provides new information regarding microRNA function in cellular homeostasis of zebrafish

Cellular pathways represent the intricate metabolic connections between the plethora of signaling pathways, and energetic-sensors in organs.

11 Dec 2018

New study reveals yin-yang personality of dopamine

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which leads to addiction.

11 Dec 2018

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers from the Spanish Research Council at the Centre for Research in Agricultural Genomics and the Institute for Plant Molecular and Cellular Biology, in collaboration with the IATA, have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in plants.

10 Dec 2018

Researchers report novel findings on plant hormone

Jasmonic acid is not just the aromatic odor of the plant Jasminum grandiflorum used in cosmetics and perfume industries. Plants wounded by e.g. chewing herbivores produce jasmonic acid as a defense signal, as a phytohormone to mount their defense responses - this includes for example the formation of toxic substances.

10 Dec 2018

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Proteins are polymers of amino acids that are linked by peptide bonds and they are one of the major classes of bio-molecules existing in a living organism. Proteins are involved in various cellular functions and events like cell signaling, cell adhesion, metabolic reactions, in the generation of immune response and many more.

10 Dec 2018

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

The placenta offers an abundant source of placenta-derived mesenchymal stem cells (pMSCs), which a new study has shown can readily form cell sheets that could be implanted in children with congenital heart defects and offer benefits for heart repair and regeneration compared to commonly used synthetic material-based scaffolds. Congenital heart disease is the leading cause of birth-defect-related illness and death.

9 Dec 2018

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

For the first time, a research team at Lund University in Sweden has successfully reprogrammed mouse and human skin cells into immune cells called dendritic cells.

9 Dec 2018

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Today, the Chan Zuckerberg Initiative announced funding for open-source software efforts to improve image analysis and visualization in biomedicine. Microscopy -- critical to modern cell biology -- generates large volumes of complex data that pose significant challenges for analysis and visualization.

7 Dec 2018

Study sheds new light on microtubule binding proteins and microtubule dynamics

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections.

6 Dec 2018

Researchers identify new type of T cell that could play role in cancer, other diseases

Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute for Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to recognize phospholipids, the molecules that help form cells' outer membranes.

6 Dec 2018

Subset of immune B cells delays onset of type 1 diabetes in animal model

Researchers have conducted a study showing that a specific subset of immune B cells delays the onset of type 1 diabetes in mice.

6 Dec 2018

Jawless fish study provides a new story for inner ear evolution

Researchers at the RIKEN Center for Biosystems Dynamics (BDR) and collaborators have described for the first time the development of the hagfish inner ear. Published in the journal Nature, the study provides a new story for inner ear evolution that began with the last common ancestor of modern vertebrates.

6 Dec 2018

Researchers achieve breakthrough in blood vessel engineering

When someone has a deadly disease or sustains a life-threatening injury, a transplant or graft of new tissue may be the best -- or only -- treatment option.

6 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

Cell Biology

Researchers develop new system for efficiently producing human norovirus

Study provides new information regarding microRNA function in cellular homeostasis of zebrafish

New study reveals yin-yang personality of dopamine

Researchers shed new light on how to combat Shiga and ricin toxins

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers report novel findings on plant hormone

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Study sheds new light on microtubule binding proteins and microtubule dynamics

Researchers identify new type of T cell that could play role in cancer, other diseases

Subset of immune B cells delays onset of type 1 diabetes in animal model

Jawless fish study provides a new story for inner ear evolution

Researchers achieve breakthrough in blood vessel engineering

Researchers create new light-activated tools for controlling neurons

New massive sequencing platform implemented for double factor preimplantation genetic testing

Functional ultrasound imaging can reveal brain activity maps of mice for specific behaviors

Researchers find evidence of epigenetics in single-celled archaea

Researchers take a step forward with a study of molecules of DNA

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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