Cell Biology

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Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Pathogenic bacteria find safe harbor deep in the gastric glands to maintain colonization

Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach.

3 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Novel chemical probe enables live imaging of brain immune cells

Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain.

3 May 2019

Potential stem cell therapies moving from lab bench to clinical application

Stem cell research is leading to potential new therapies to treat disease, with several applications in clinical trials or expected to enter trials in the coming months.

3 May 2019

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Glioblastoma is an incurable type of brain tumor that is frequently associated with mutations in the epidermal growth factor receptor.

3 May 2019

Researchers use 3D printer to make paper organs

Long before scientists test new medicines in animals or people, they study the effects of the substances on cells growing in Petri dishes.

1 May 2019

Army research may help improve cancer treatments and treat combat wounds

Army research is the first to develop computational models using a microbiology procedure that may be used to improve novel cancer treatments and treat combat wounds.

1 May 2019

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

In the majority of cases, dementia can be traced back to Alzheimer's disease. Its causes are not really understood yet. What is known is that plaques form from misfolded proteins and that there is an increase in neuronal cell death levels in the brain. However, the plaques don't necessarily go hand in hand with any symptoms.

30 Apr 2019

Scientists develop small fluorophores for tracking metabolites in living cells

Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult.

30 Apr 2019

Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

How proteins in outer membrane of bacteria stick to and populate in human body

The discovery, published today in Nature Communications by researchers from La Trobe University and the University of Queensland, provides details on how proteins in the outer membrane of bacteria - the bacteria's 'superglue' - are able to stick to and populate parts of the human body.

30 Apr 2019

Researcher studies two protein families known to play role in cancer metastasis

In a paper published in the Journal of Biological Chemistry, Dr. özdemir has studied two protein families named Rho GTPases and IQGAPs, which are known to play an important role in cancer metastasis.

30 Apr 2019

Study describes new viral molecular evasion mechanism used by cytomegalovirus

A study published in the journal PLOS Pathogens describes a new viral molecular evasion mechanism used by cytomegalovirus to interfere in the immune response of the infected host.

30 Apr 2019

Reproducible and validatable sterilization at Labvolution 2019

Systec GmbH will present its autoclaves, media preparators and dispensing and dosing solutions for microbiological culture media at Labvolution 2019.

From Systec GmbH 29 Apr 2019

Researchers discover how an executioner mechanism is triggered to kill damaged cells

Researchers led by St. Jude Children's Research Hospital structural biologists have discovered how the cell switches on an executioner mechanism called necroptosis that induces damaged or infected cells to commit suicide to protect the body.

27 Apr 2019

TET proteins help regulate gene activity vital for normal antibody production

A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear how genes were activated by TET proteins to make sure that cells perform their normal functions efficiently.

27 Apr 2019

Cell Biology

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

Pathogenic bacteria find safe harbor deep in the gastric glands to maintain colonization

Scientists describe how cells 'decide' between pluripotency and differentiation

Novel chemical probe enables live imaging of brain immune cells

Potential stem cell therapies moving from lab bench to clinical application

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Researchers use 3D printer to make paper organs

Army research may help improve cancer treatments and treat combat wounds

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

Scientists develop small fluorophores for tracking metabolites in living cells

Researchers use structural biology techniques to understand how lipids bind proteins

How proteins in outer membrane of bacteria stick to and populate in human body

Researcher studies two protein families known to play role in cancer metastasis

Study describes new viral molecular evasion mechanism used by cytomegalovirus

Reproducible and validatable sterilization at Labvolution 2019

Researchers discover how an executioner mechanism is triggered to kill damaged cells

TET proteins help regulate gene activity vital for normal antibody production

Scientists aim to unlock the secrets of heart cells

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Biologists unravel new role for nervous system in regeneration

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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