Cell Biology

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Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Study illuminates how the brain senses infection

A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.

8 Mar 2023

Study may provide a new target for treatment of Alzheimer's disease

Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer's disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China.

7 Mar 2023

A shot of liver-produced hormone sobers up drunk mice

A hormone called fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study publishing on March 7 in the journal Cell Metabolism.

7 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

Newfound mechanism helps the heart to toggle between maintenance and energy-boost mode

Researchers at the Centre for Genomic Regulation in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day function and an 'energy-boost mode' which aids recovery for high-demand situations including heart attacks.

7 Mar 2023

Research helps explain the metabolic differences of people living at high altitudes

Compared to those of us who live at sea level, the 2 million people worldwide who live above 4,500 meters (or 14,764 feet) of elevation - about the height of Mount Rainier, Mount Whitney, and many Colorado and Alaska peaks - have lower rates of metabolic diseases such as diabetes, coronary artery disease, hypercholesterolemia, and obesity.

7 Mar 2023

Study examines the effects of microgravity on human immune system

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

7 Mar 2023

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central nervous system and the second most common of all structural birth defects.

6 Mar 2023

'Good autoantibodies' associated with a milder course and lower risk of long Covid

Sometimes in the laboratory there are unexpected results. "Previously it had been observed that autoantibodies are common in severe Covid patients, those who end up in intensive care," says Jonathan Muri, postdoctoral fellow at the Institute for Research in Biomedicine (IRB, affiliated with the Università della Svizzera italiana) and co-author of the study.

6 Mar 2023

New research pinpoints key culprit behind brain cancer metastasis in children

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

6 Mar 2023

Researchers discover a new mutation that leads to arrhythmogenic cardiomyopathy

Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).

5 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

New way to carry drugs across the blood-brain barrier using nanoparticles

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Researchers at Tohoku University have shown that astrocytes - star-shaped glial cells that control the local ionic and metabotropic environment of the brain - exhibit an acid response with REM sleep in mice.

3 Mar 2023

Festo advances high-throughput automated pipetting with closed-loop control

Festo introduces the DHOP closed-loop pipette head for high-speed robotic pipetting applications requiring consistent volumes over a wide range of liquid viscosities. The DHOP pipette head provides the utmost in automation flexibility, speed, and feedback when devices handle many liquids.

From Festo Ltd. 2 Mar 2023

Festo breaks price/performance barriers with new multi-axis gantry

Festo introduces the EXCL, a multi-axis gantry kit that lowers acquisition, engineering, and assembly costs for automated sample handling and liquid dispensing in laboratory devices.

From Festo Ltd. 2 Mar 2023

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer — altering cancer cells so that they teach the body's immune system to fight the very cancer the cells came from.

2 Mar 2023

Biologists discover how to awaken and reactivate neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons.

1 Mar 2023

Gut bacteria influence the liver's regenerative ability

When parts of the liver are removed, the body can replace the missing tissue. A team of researchers at the Technical University of Munich has now discovered that the success of this process depends to a large extent on gut bacteria.

1 Mar 2023