Cell Biology

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Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown.

23 Jun 2023

Eliminating cancer cell repopulation may be the key to curing cancer

A new research perspective was published in Oncoscience (Volume 10) on June 1, 2023, entitled, "Cancer cell repopulation after therapy: which is the mechanism?"

23 Jun 2023

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology.

23 Jun 2023

Scientists discover new way to defeat invisible cancer cells

Modern immunotherapies boost the body's own defenses against cancer. They activate killer T cells of the immune system that can specifically recognize and destroy cancer cells.

23 Jun 2023

Research sheds light on how steroids affect cancer Immunotherapy

Immunotherapy is among the newest and most potent weapons against cancer. It prompts the immune system to recognize tumors as intruders in the body and attack. But not all patients respond well to immunotherapy. Why? Scientists aren't always sure.

23 Jun 2023

Cell and gene therapy CDMO Andelyn Biosciences celebrates over 20 years of leadership and innovation with opening of new 180,000 square foot manufacturing headquarters

Andelyn Biosciences, a pioneer in the development and manufacturing of cell and gene therapies, today formally inaugurates its new manufacturing headquarters, the Andelyn Corporate Center (ACC), located in the Innovation District in Columbus, Ohio.

From Andelyn Biosciences 23 Jun 2023

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.

23 Jun 2023

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Alzheimer's disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis – the formation and development of an embryo.

22 Jun 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery."

21 Jun 2023

New insights into lymphatic cell migration and lymphatic vessel remodeling

Lymphangiogenesis refers to the formation and remodeling of lymphatic vessels (a network of thin tubes that carry lymph in the lymphatic system), and it supports the transport of molecules and immune cells around the body.

21 Jun 2023

Rensselaer investigator awarded $1.6 million grant to study the mechanics of mitosis to fight cancer

It is a scary fact that one in two women and one in three men in the United States will develop some form of cancer in their lifetime.

20 Jun 2023

New embryonic cell type that self-destructs to protect the developing fetus discovered

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell which self-destructs within days of forming, as part of a quality control process to protect the developing fetus.

20 Jun 2023

Researchers use an unprecedented stem cell zoo to study developmental time

In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development differs substantially across animals.

20 Jun 2023

Study highlights the role of high cholesterol in SARS-CoV-2 infectivity

A recent study unveiled the doorway that SARS-CoV2 uses to slip inside cells undetected.

20 Jun 2023

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current.

19 Jun 2023

Molecular cargo released by cancer cells lays the groundwork for leukemia spread

Tiny packets of molecular cargo shed by cancer cells seed the foundations for metastasis at distant sites in the body.

19 Jun 2023

Opentrons partners with Zymo Research to automate key microbiome chemistries on the Opentrons Flex™

Opentrons Labworks, Inc., a leader in lab automation and makers of accessible lab robotics and Zymo Research Corp, a life science reagent company, are collaborating to transform microbiome and metagenome analysis by fully automating comprehensive, end-to-end workflows from sample collection through library preparation on the Opentrons Flex.

From Opentrons 19 Jun 2023

New method can create plant-based meat substitutes with better texture

Sales of plant-based meat products have levelled off in recent years, at least in part because current offerings lack the texture or mouthfeel of a nice T-bone steak or chicken breast.

18 Jun 2023

Destroying the tether of shattered chromosomal fragments may help prevent cancerous mutations

Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division.

15 Jun 2023

Cell Biology

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

Eliminating cancer cell repopulation may be the key to curing cancer

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Scientists discover new way to defeat invisible cancer cells

Research sheds light on how steroids affect cancer Immunotherapy

Cell and gene therapy CDMO Andelyn Biosciences celebrates over 20 years of leadership and innovation with opening of new 180,000 square foot manufacturing headquarters

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Brain organoids provide new insights into HSV-1 encephalitis

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

New insights into lymphatic cell migration and lymphatic vessel remodeling

Rensselaer investigator awarded $1.6 million grant to study the mechanics of mitosis to fight cancer

New embryonic cell type that self-destructs to protect the developing fetus discovered

Researchers use an unprecedented stem cell zoo to study developmental time

Study highlights the role of high cholesterol in SARS-CoV-2 infectivity

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Molecular cargo released by cancer cells lays the groundwork for leukemia spread

Opentrons partners with Zymo Research to automate key microbiome chemistries on the Opentrons Flex™

New method can create plant-based meat substitutes with better texture

Destroying the tether of shattered chromosomal fragments may help prevent cancerous mutations

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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