Cell Biology

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Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Scientists have developed a synthetic extracellular matrix (ECM) that can support the growth of a mini endometrium in a dish for at least two weeks.

11 Aug 2023

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

A research team led by Prof. ZHU Shu from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) illustrated the role of Gasdermin D (GSDMD) protein in immunity tolerance to food in the small intestine.

11 Aug 2023

Brain development linked to the emergence of autism spectrum disorder

Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new Yale-led study in which researchers developed brain organoids from the stem cells of boys diagnosed with the disorder.

10 Aug 2023

Scientists develop new technique to "tattoo" living cells with nanomaterials

For now, cyborgs exist only in fiction, but the concept is becoming more plausible as science progresses.

10 Aug 2023

Study provides clues to how harmful T cells cause heart disease

Scientists can finally hunt down a harmful kind of human T cell, thanks to new research led by scientists at La Jolla Institute for Immunology (LJI) and the Medical College of Georgia (MCG) at Augusta University.

10 Aug 2023

New pathway for HIV to enter nucleus of healthy cells identified

A study published on August 10, 2023 in the journal Nature Communications has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells.

10 Aug 2023

MaxCyte signs strategic platform license with Lyell Immunopharma

From MaxCyte, Inc. 10 Aug 2023

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, and Vittoria Biotherapeutics (Vittoria), a leading edge, gene-edited cell therapeutics company with novel platform technologies poised to develop a pipeline of highly differentiated cellular therapies for both oncology and immunology indications, today announced the signing of a strategic platform license (SPL) of MaxCyte’s Flow Electroporation® technology and ExPERT™ platform to Vittoria Biotherapeutics.

From MaxCyte, Inc. 10 Aug 2023

MaxCyte signs strategic platform license with prime medicine to advance next-generation gene editing therapies for patients

From MaxCyte, Inc. 10 Aug 2023

Fruit fly study provides insights into piRNA production and fertility

You're likely familiar with RNA, the molecule that plays an important role in protein production and gene expression control.

9 Aug 2023

New mechanism discovered for coordinating organ development

Researchers at the Instituto Gulbenkian de Ciência (IGC, Oeiras) and Max Planck Institute of Cell Biology and Genetics (MPI-CBG, Dresden) identified a new mechanism that exposes some of the multitasking abilities embryos need to build a functional retina, the sensory part of the central nervous system responsible for vision.

9 Aug 2023

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown.

9 Aug 2023

Ebola virus forms "viral factories" to replicate inside host cells

New research in the journal Nature Communications gives scientists an important window into how Ebola virus replicates inside host cells.

9 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

RAGE plays key role in cellular mechanisms of plasticity in aggressive triple-negative breast cancer

Published online ahead of print in the journal Oncogene , a study led by Josep Villanueva, an Investigator at the Vall d'Hebron Institute of Oncology (VHIO), shows that the receptor for advanced glycation end-product (RAGE) plays a key role in cellular mechanisms of plasticity in mesenchymal triple-negative breast cancer (TNBC) that transform epithelial cells into mesenchymal cells as potent drivers of cancer cell proliferation and tumor invasion.

8 Aug 2023

Cell Biology

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

Brain development linked to the emergence of autism spectrum disorder

Scientists develop new technique to "tattoo" living cells with nanomaterials

Study provides clues to how harmful T cells cause heart disease

New pathway for HIV to enter nucleus of healthy cells identified

MaxCyte signs strategic platform license with Lyell Immunopharma

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

MaxCyte signs strategic platform license with prime medicine to advance next-generation gene editing therapies for patients

Fruit fly study provides insights into piRNA production and fertility

New mechanism discovered for coordinating organ development

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

Ebola virus forms "viral factories" to replicate inside host cells

NLRP3 inflammasome plays a role in podocyte aging

RAGE plays key role in cellular mechanisms of plasticity in aggressive triple-negative breast cancer

Cytochromes P450 enzymes exhibit unique soft-robotic properties, study reveals

Nanoscale tattoos for tracking the health of individual cells

Mitochondrial protein structure activates cell's integrated stress response

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

Deep learning improves protein design by 10x

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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