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Immunoproteasome inhibits repair function of alveolar macrophages

Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research, have observed that the immunoproteasome inhibits the repair function of alveolar macrophages.

22 Mar 2016

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Understanding the origins of emerging diseases - as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite's ability to cause infected red blood cells to bind to the inner lining of blood vessels.

22 Mar 2016

New reference guide can help HIV care providers treat chronic pain

Recent studies suggest many individuals with HIV have chronic pain. Estimates range from 39 percent all the way to 85 percent. Chronic pain is an important comorbid condition in individuals with HIV, as it is common and causes substantial disability.

22 Mar 2016

TGen investigators help track hypervirulent strep outbreak in southwestern U.S.

The Translational Genomics Research Institute (TGen) has helped state, local and tribal health officials identify an outbreak of "hypervirulent" strep bacteria in the American Southwest.

22 Mar 2016

Sandia engineers aim to develop autonomous device to passively monitor mosquito-borne diseases

Mosquitoes are deadly efficient at spreading disease. Despite vaccines and efforts to eradicate the pesky insects, they continue to infect humans with feared diseases like Zika virus, malaria and West Nile virus.

22 Mar 2016

Antibodies given within one day of SHIV exposure can clear the virus

Scientists at the Oregon National Primate Research Center today revealed that infant rhesus macaques treated with antibodies within 24 hours of being exposed to SHIV, a chimeric simian virus that bears the HIV envelope protein, were completely cleared of the virus.

22 Mar 2016

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

The largest genetic study on the bacterium responsible for epidemic dysentery has revealed that the Shigella dysenteriae pathogen, which remains a real scourge in Africa and Asia, probably originated in Europe.

22 Mar 2016

World TB Day 2016: WHO calls to Unite to End TB

In advance of World TB Day, to be observed on 24 March, the World Health Organization is calling on countries and partners to Unite to End TB.

22 Mar 2016

Scientists look for new antibiotic drugs in unexpected places

Many of the drugs we use in hospitals – antibiotics, antifungals and anti-cancer drugs, to name but a few – are produced by bacteria that live in the soil beneath our feet.

22 Mar 2016

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Takeda Pharmaceutical Company Limited, (“Takeda”) today announced that the interim findings from the GEMINI Long-Term Safety (LTS) study were presented during the 2016 European Crohn's and Colitis Organisation (ECCO) Annual Scientific Meeting in Amsterdam, The Netherlands.

22 Mar 2016

World TB Day: Aeras releases new animated video to help raise awareness about TB

Aeras, a non-profit biotechnology organization developing new tuberculosis (TB) vaccines for the world, is launching a new 90-second animated video in honor of World TB Day to help raise awareness about TB’s devastating toll and the need for new tools, including vaccines, to fight this epidemic.

22 Mar 2016

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine.

22 Mar 2016

Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS.

22 Mar 2016

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

New research indicates that mycophenolate mofetil, a drug that is usually used to prevent rejection after kidney, heart or liver transplant, seems safe and effective in treating autoimmune hepatitis (AIH), a serious chronic liver disease that mainly affects women.

22 Mar 2016

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

On Friday, March 18, the U.S. Food and Drug Administration approved Anthim (obiltoxaximab) injection to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

21 Mar 2016

Researchers disprove previously assumed behavior of macrophage immune cells

What happens when macrophage immune cells are activated in the course of an inflammation to combat pathogens such as bacteria or viruses? Researchers of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg pursued this very question. The researchers discovered that the immune cells behave differently from what was previously assumed. Their metabolism upholds the production of antimicrobial substances and fatty acids during activation. In this way, they deliver important resources for the immune responses they trigger.

21 Mar 2016

Disease/Infection News

Immunoproteasome inhibits repair function of alveolar macrophages

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

New reference guide can help HIV care providers treat chronic pain

TGen investigators help track hypervirulent strep outbreak in southwestern U.S.

Sandia engineers aim to develop autonomous device to passively monitor mosquito-borne diseases

Antibodies given within one day of SHIV exposure can clear the virus

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

World TB Day 2016: WHO calls to Unite to End TB

Scientists look for new antibiotic drugs in unexpected places

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

World TB Day: Aeras releases new animated video to help raise awareness about TB

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Specialized gene editing system paves way to eventual cure for HIV patients

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

Researchers disprove previously assumed behavior of macrophage immune cells

Advanced genomic sequencing tracks deadly blood infection in cancer patients

Computer-assisted methods may help as decision support system to combat Zika virus

WHO sends experts to monitor Zika virus in Cabo Verde

Preventing blindness through portable eye examinations: an interview with Dr Mario Ettore Giardini

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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