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Brigham researchers quantify the burden of SARS-CoV-2-associated sepsis

Using data from Mass General Brigham's electronic health records, Brigham researchers quantified the burden of SARS-CoV-2-associated sepsis early in the pandemic.

29 Sep 2023

Researchers develop an improved way to test potential vaccines against bird flu

Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

29 Sep 2023

New artemisinin-resistant malaria parasite detected in Eritrea

Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa.

29 Sep 2023

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

29 Sep 2023

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during early months of the pandemic

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during the first 33 months of the COVID-19 pandemic, highlighting the importance of viral sepsis, according to a new study led by researchers at the Harvard Pilgrim Health Care Institute.

29 Sep 2023

New research uncovers autozygosity's impact on common disease risks

Researchers explored the associations between autozygosity, measured as the fraction of the genome in runs of homozygosity (FROH), and common diseases, focusing on populations with high consanguinity rates.

29 Sep 2023

The fight against cancer: a comprehensive assessment of preventable and treatable cases

Researchers presented the findings of a population-based study conducted across 185 countries to estimate premature deaths due to 36 different types of cancers in 2020, a leading cause of premature deaths worldwide.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

Sushi and other raw seafood can spread antibiotic-resistant bacteria, study warns

Bacteria in raw seafood can make you sick. Seafood can also spread bacteria that are resistant to antibiotics.

28 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Plastic waste in the oceans may spread antibiotic resistance

Bacteria discharged to the oceans in sewage and wastewater thrive on the biofilms that form on plastic waste. This may be leading to the somewhat unanticipated problem of antimicrobial resistance.

28 Sep 2023

Weighing the risks and benefits of COVID-19 precautions in 2023

A new editorial paper was published in Oncotarget's Volume 14 on September 22, 2023, entitled, "Reassessing the risks and benefits of COVID-19 precautions in 2023."

28 Sep 2023

Social isolation linked to higher depression levels during the COVID-19 pandemic

Higher levels of depressive symptoms have been reported during the COVID-19 pandemic compared with other times in history, and as much as three times higher than prior to the pandemic.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

Commonly used anti-viral drugs reduce risk of hospitalization, death in patients with mild COVID-19

New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with Omicron subvariants.

28 Sep 2023

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients displayed abnormalities in multiple organs five months after infection, some of which have been shown through previous work to be evidence of tissue damage.

28 Sep 2023

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.

28 Sep 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Disease/Infection News

Brigham researchers quantify the burden of SARS-CoV-2-associated sepsis

Researchers develop an improved way to test potential vaccines against bird flu

New artemisinin-resistant malaria parasite detected in Eritrea

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during early months of the pandemic

New research uncovers autozygosity's impact on common disease risks

The fight against cancer: a comprehensive assessment of preventable and treatable cases

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

Sushi and other raw seafood can spread antibiotic-resistant bacteria, study warns

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Plastic waste in the oceans may spread antibiotic resistance

Weighing the risks and benefits of COVID-19 precautions in 2023

Social isolation linked to higher depression levels during the COVID-19 pandemic

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

Commonly used anti-viral drugs reduce risk of hospitalization, death in patients with mild COVID-19

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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