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Could next-generation antimicrobial agents act as an alternative to standard antibiotics?

Next-generation antimicrobial agents (NGAs) as a potential alternative to standard antibiotics

26 Sep 2023

Insomnia's toll on the heart: study highlights cardiovascular event risks

Researchers performed a meta-analysis to evaluate the incidence of cardiovascular (CV) events among individuals with insomnia.

26 Sep 2023

How the COVID-19 pandemic affected mental well-being of UK secondary school students

Researchers evaluated the impact of COVID-19 on the mental health of secondary school children in the UK.

26 Sep 2023

How does long covid impact the school experiences of children and young people?

The impact of long covid on school experiences.

26 Sep 2023

One health wake-up call: London's river data highlights environmental perils

The largest-ever spatiotemporal monitoring of chemicals/contaminants of emerging concern (CECs) in London waterways.

26 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Hospitalized COVID-19 patients face triple the risk of multiorgan damage, study reveals

Researchers in the U.K. find that patients hospitalized with COVID-19 face a higher medium-term risk of multiorgan abnormalities, revealed through multiorgan MRI scans. The study emphasizes the urgency for comprehensive post-hospitalization care, as these abnormalities are associated with persistent mental and physical health impairments.

25 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Antibiotics can sometimes benefit bacteria

Scientists have found a surprising effect of some antibiotics on certain bacteria – that the drugs can sometimes benefit bacteria, helping them live longer.

25 Sep 2023

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Researchers at the Francis Crick Institute, the University of Cambridge, Imperial College London, the University of Liverpool, the University of Cape Town and UKHSA have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.

25 Sep 2023

Engineered mice reveal how Omicron subvariant BA.5 is more virulent

New research used engineered mice to compare SARS-COV-2 omicron subvariants and found one of them – BA.5 – was more virulent likely due to its ability to rapidly replicate early during infection.

25 Sep 2023

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

25 Sep 2023

Future-proof vaccine candidate protects against wide range of coronaviruses

Studies of a 'future-proof' vaccine candidate have shown that just one antigen can be modified to provide a broadly protective immune response in animals.

25 Sep 2023

Long COVID patients exhibit different immune and hormonal responses to the virus, study shows

People who have experienced brain fog, confusion, pain, and extreme fatigue for months or longer after being infected with the COVID-19 virus exhibit different immune and hormonal responses to the virus than those not diagnosed with long COVID, according to a new study by researchers at Yale School of Medicine and Icahn School of Medicine at Mount Sinai.

25 Sep 2023

New injectable solution could help manage HIV unlike any current treatment methods

A new injectable solution that self-assembles into a gel under the right conditions could help manage HIV unlike any currently available methods, researchers have found.

25 Sep 2023

Is the implementation of contact precautions crucial for preventing healthcare-associated MRSA?

The designation of contact precautions as an "essential practice" for MRSA prevention.

25 Sep 2023

The power of nanobodies: How they impact COVID-19 immune response

The structures of 340 antibodies (Abs) and 83 nanobodies.

25 Sep 2023

COVID-19 pushed upstate New Yorkers to embrace backyard farming

During the COVID-19 pandemic, upstate New Yorkers turned to backyard and wild food production to gain more control over their food supply, according to a study by Cornell University. The research highlights how the pandemic-related disruptions in conventional food supply chains led to a significant uptick in gardening, poultry rearing, and foraging as a strategy to improve food security.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023