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Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Moderna's updated mRNA-1273.815 COVID-19 vaccine shows promising results in reducing symptomatic cases, hospitalizations, and deaths in high-risk and older adults in Germany. The study finds the vaccine to be more cost-effective and clinically beneficial than both no vaccination and Pfizer's XBB.1.5 BNT162b2 vaccine.

12 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Researchers have developed EVScape, a predictive tool that identifies which SARS-CoV-2 strains are most likely to evade host immunity. Utilizing a deep generative model and structural information, the tool offers early warning about viral variants, aiding in the timely development of effective vaccines and treatments.

12 Oct 2023

Generic PrEP use could reduce new HIV acquisitions, save lives among young men who have sex with men

Anne Neilan, MD, a physician-scientist in the division of Infectious Diseases at Massachusetts General Hospital is the senior author of a recently published paper in Clinical Infectious Diseases, Daily Oral HIV Pre-exposure Prophylaxis Among Young Men Who Have Sex With Men in the United States: Cost-Saving at Generic Drug Price.

12 Oct 2023

Invasive mosquito species may be spreading new form of malaria in East Africa

Turkana County in northwestern Kenya was supposed to be the land that malaria forgot. An arid, windy region abutting Uganda, South Sudan and Ethiopia, its climate was thought to be too dry for the mosquitoes that harbor malaria-causing parasites, and thus it has been excluded from national efforts to prevent the spread of the disease.

12 Oct 2023

New study finds host strategy to cope with sleeping sickness

A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology found a new strategy by the host to cope with Trypanosoma brucei infection.

12 Oct 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

Fighting tuberculosis: Breakthrough analysis reveals mixed strain infections

The drug-resistant genotypes in mixed strain infection (MSI) samples of Mycobacterium tuberculosis.

12 Oct 2023

PrEP, a key HIV prevention tool, isn’t reaching Black women

Alexis Perkins thought her OB-GYN's office in Atlanta would be just the place to get a prescription for the type of drug that reduces a person's risk of contracting HIV.

12 Oct 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Healthcare settings and mpox transmission: Understanding the risk factors

The stability of the monkeypox (Mpox) virus in various surroundings and bodily fluid.

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

UVA scientists’ efforts could help better combat antibiotic-resistant bacteria

University of Virginia researchers are working to outrace two dangerous germs known for quickly developing resistance to new antibiotics – and the scientists’ efforts could help us better combat antibiotic resistance more broadly.

12 Oct 2023

Genetically edited chickens show resistance to avian influenza in landmark study

Researchers use CRISPR technology to create chickens resistant to avian influenza, targeting specific genes to inhibit viral replication. The study reveals both the promise and complexities of using genetic editing as a disease control strategy, also shedding light on influenza's adaptability.

11 Oct 2023

Maternal pertussis vaccination boosts infant protection up to eight months

In a large-scale Australian study, maternal vaccination during pregnancy significantly increased pertussis resistance in infants up to eight months. While it slightly reduced the effectiveness of infants' routine vaccinations, it did not increase infection risk.

11 Oct 2023

Disease/Infection News

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Generic PrEP use could reduce new HIV acquisitions, save lives among young men who have sex with men

Invasive mosquito species may be spreading new form of malaria in East Africa

New study finds host strategy to cope with sleeping sickness

Does your gut microbiome play a role in therapeutic outcomes?

Fighting tuberculosis: Breakthrough analysis reveals mixed strain infections

PrEP, a key HIV prevention tool, isn’t reaching Black women

Is there an association between vitamin D deficiency and sepsis mortality?

Healthcare settings and mpox transmission: Understanding the risk factors

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

UVA scientists’ efforts could help better combat antibiotic-resistant bacteria

Genetically edited chickens show resistance to avian influenza in landmark study

Maternal pertussis vaccination boosts infant protection up to eight months

New AI tool predicts future viral variants using evolutionary, biological information

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

How were antibiotics used during the COVID-19 pandemic?

Presidential advisory by the American Heart Association: connecting cardiovascular, kidney, and metabolic health

Feds hope to cut sepsis deaths by hitching Medicare payments to treatment stats

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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