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Geranium plant extracts prevent HIV-1 from invading human cells

Extracts of the geranium plant Pelargonium sidoides inactivate human immunodeficiency virus type 1 (HIV-1) and prevent the virus from invading human cells. In the current issue of "PLOS ONE", scientists from the Helmholtz Zentrum München report that these extracts represent a potential new class of anti-HIV-1 agents for the treatment of AIDS.

30 Jan 2014

Scientists to develop faster method for pathogen screening in food products

The regular appearance of food poisoning in the news, including a recent event that led to the recall of more than 33,000 pounds of chicken, drives home the need for better bacterial detection long before meats and produce make it to the dinner table.

30 Jan 2014

CONRAD receives USAID Pioneers Prize for developing tenofovir gel to reduce HIV infection in women

CONRAD, a leading reproductive health-research organization based at Eastern Virginia Medical School (EVMS), today announced that they are a winner of the United States Agency for International Development (USAID) Science and Technology Pioneers Prize for their work in developing tenofovir gel.

29 Jan 2014

Researchers identify chemical substance to treat bacterial infections

Increasing numbers of bacteria are developing antibiotic resistance. This forms a significant challenge in the battle against bacterial infections. Alvin Lo and Han Remaut (VIB/Vrije Universiteit Brussel) have identified a chemical substance with the potential of acting as a new drug to treat bacterial infections, particularly urinary tract infections.

29 Jan 2014

Study suggest that unique environmental stimulus may interact with genetic trait to initiate type 1 diabetes

Type 1 diabetes is a genetically-driven autoimmune disease of pancreatic beta-cells, whose origins remain unknown. Researchers at the Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) discovered that skin cells from patients with type 1 diabetes display abnormal activity triggered by immune response mechanisms to environmental stimuli like a viral infection.

29 Jan 2014

Biologists identify protein targets for next-generation of anti-HIV drugs

People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos.

29 Jan 2014

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

The product has proven efficiency in lab tests, although clinical trials are yet to be performed. After discovering that silver nanoparticles are capable of blocking the entry of Human Immunodeficiency Virus (HIV) into the organism, a group of researchers from the University of Texas, in collaboration with Humberto Lara Villegas, specialist in nanoparticles and virology from the University of Monterrey, Mexico (UDEM), create a vaginal cream to control the transmition of the virus.

28 Jan 2014

Patients' race or ethnicity linked with differences in prescription of HIV drug

A lot of evidence shows that a patients' race or ethnicity is associated with differences in how health care providers communicate with them, the health care they receive, and their health outcomes.

28 Jan 2014

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

St. Jude Children's Research Hospital scientists have discovered a promising new class of antibiotics that could aid efforts to overcome drug-resistance in tuberculosis (TB), a global killer.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

FOB Synthesis enters into license agreement with AstraZeneca to treat drug-resistant bacterial infections

FOB Synthesis, Inc. has entered into a research and development option and license agreement with AstraZeneca for the development of a novel antibiotic to treat drug-resistant bacterial infections.

28 Jan 2014

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Scientists have begun the first human clinical trial of EDP-788, an investigational oral antibiotic intended to treat methicillin-resistant Staphylococcus aureus (MRSA) infections.

27 Jan 2014

Study finds new class of semisynthetic anti-tuberculosis agents that overcome native drug efflux

Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have developed a method to synthesize modified forms of an established antibiotic called spectinomycin.

27 Jan 2014

NIBIO signs collaboration agreement for clinical development of new mucosal TB vaccines

Japan's National Institute of Biomedical Innovation ("NIBIO"), Aeras and Create Vaccine Company, Ltd ("CREATE") announce today that they signed a collaboration agreement on December 26, 2013, on the preclinical and clinical development of new mucosal tuberculosis (TB) vaccines based on NIBIO's human parainfluenza type-2 (rhPIV2) vector technology.

27 Jan 2014

E.R. expert warns public about 5 things doctor may do wrong when treating for flu

The flu season is in full swing starting mostly in the second week of January when emergency rooms are more busy than usual with patient with flu like symptoms. Dr. James Kojian, E.R. expert and founder of DRTOHELP.COM, warns the public about five things your doctor may be doing wrong when treating for the flu.

25 Jan 2014

Scientists, clinicians to examine role of human gut microbiota in digestive and overall health

The microbial communities that reside in the human gut and their impact on human health and disease are one of the most exciting new areas of research today. To address the most recent advances in this rapidly developing field, scientists and health-care professionals from all over the world will come together at the Gut Microbiota for Health World Summit in Miami, Florida, on March 8 and 9, 2014.

24 Jan 2014

Salmonella infections can reduce incidence of asthma, say researchers

Researchers from Germany have identified the mechanism by which Salmonella infections can reduce the incidence of asthma in mice. The research, which appears ahead of print in the journal Infection and Immunity, opens up new avenues of research that could lead to treatments.

24 Jan 2014

New technique detects bacterium that causes Legionnaires’ disease

The bacterium that causes Legionnaires’ disease remains difficult to track. French researchers have now developed a new technique that should allow living representatives of this dangerous pathogen to be detected much more quickly than with conventional methods. As they report in the journal Angewandte Chemie, samples are exposed to an azide-modified compound that the pathogen specifically incorporates into its shell, which is made of saccharide units. A fluorescent marker attached to the azide groups is used to identify the pathogen.

24 Jan 2014

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

24 Jan 2014

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

AIDS researchers from Case Western Reserve University and University Hospitals Case Medical Center have received a seven-year funding award from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

23 Jan 2014

Disease/Infection News

Geranium plant extracts prevent HIV-1 from invading human cells

Scientists to develop faster method for pathogen screening in food products

CONRAD receives USAID Pioneers Prize for developing tenofovir gel to reduce HIV infection in women

Researchers identify chemical substance to treat bacterial infections

Study suggest that unique environmental stimulus may interact with genetic trait to initiate type 1 diabetes

Biologists identify protein targets for next-generation of anti-HIV drugs

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

Patients' race or ethnicity linked with differences in prescription of HIV drug

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

Researchers discover unusually large bacteriophage that infects anthrax bacterium

FOB Synthesis enters into license agreement with AstraZeneca to treat drug-resistant bacterial infections

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Study finds new class of semisynthetic anti-tuberculosis agents that overcome native drug efflux

NIBIO signs collaboration agreement for clinical development of new mucosal TB vaccines

E.R. expert warns public about 5 things doctor may do wrong when treating for flu

Scientists, clinicians to examine role of human gut microbiota in digestive and overall health

Salmonella infections can reduce incidence of asthma, say researchers

New technique detects bacterium that causes Legionnaires’ disease

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

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