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CLL patients more prone to infections due to reduced number of antibodies

People with chronic lymphocytic leukaemia (CLL) are essentially more prone to infections such as varicella, influenza or pneumococci due to the reduction in the number of antibodies that their condition causes.

19 Mar 2014

Dartmouth, Aeras to jointly conduct trial of DAR-901 vaccine against TB

Dartmouth's Geisel School of Medicine and Aeras, a global nonprofit biotech, announced a collaboration to jointly conduct a trial of a new vaccine against tuberculosis (TB), one of the world's deadliest diseases. The vaccine, known as DAR-901, is related to the vaccine SRL-172, previously shown by Dartmouth investigators to decrease the risk of TB in a trial known as the DarDar Trial.

19 Mar 2014

China manages to halve TB prevalence in 20 years

Over the last 20 years, China has more than halved its tuberculosis (TB) prevalence, with rates falling from 170 to 59 per 100 000 population. This unrivalled success has been driven by a massive scale-up of the directly observed, short-course (DOTS) strategy, from half the population in the 1990s to the entire country after 2000, according to findings from a 20-year-long analysis of national survey data, published in The Lancet.

19 Mar 2014

Quail and chickens are likely sources of infection of H7N9 influenza virus to humans

Among the copious species of poultry in China, quail and chickens are the likely sources of infection of H7N9 influenza virus to humans, according to a paper published ahead of print in the Journal of Virology.

19 Mar 2014

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Medivir AB today announced that new phase III data for the once-daily protease inhibitor simeprevir have been presented at the Conference of the Asian Pacific Association for the Study of the Liver (APASL) in Brisbane, Australia.

19 Mar 2014

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls.

18 Mar 2014

Sequencing reveals genetic diversity in hospital-acquired bacterium

Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

18 Mar 2014

AV drugs could help curb bacteria's growing resistance to antibiotic treatments

A new type of drug could help to combat growing antibiotic resistance, a study finds. Medicines that stop bacteria from harming their hosts, rather than kill them, could prevent bugs from evolving resistance to drug treatments, a review of research in the field suggests.

18 Mar 2014

New research commissioned to create infection control strategy for AMR and antibiotic usage

It is the health system’s nightmare, bubbling just below the surface of our hospitals. Infections are becoming more and more resistant to antibiotics, while secondary infection rates during hospital stays continue to rise.

18 Mar 2014

Patients with both HIV and hepatitis C have 80% higher rates of serious liver disease

A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has found that the risk of hepatitis C-associated serious liver disease persists in HIV patients otherwise benefitting from antiretroviral therapy (ART) to treat HIV.

18 Mar 2014

Study shows only 23% of seasonal and pandemic flu caused symptoms

Around 1 in 5 of the population were infected in both recent outbreaks of seasonal flu and the 2009 H1N1 influenza pandemic, but just 23% of these infections caused symptoms, and only 17% of people were ill enough to consult their doctor.

17 Mar 2014

L. reuteri Protectis reduces diarrhea, respiratory tract infections in healthy children

Healthy children attending day-care centres have a significantly lower risk of getting diarrhoea or respiratory tract infections when given a daily supplement of Lactobacillus reuteri Protectis, a study in 336 children shows. "Our study confirms earlier published data in proving that preventive use of L. reuteri Protectis in healthy children reduces diarrhoeic episodes.

17 Mar 2014

Honey helps fight antibiotic resistance, says study

Honey, that delectable condiment for breads and fruits, could be one sweet solution to the serious, ever-growing problem of bacterial resistance to antibiotics, researchers said here today.

17 Mar 2014

Hepatitis C patients with ITPA gene variants exhibit lower risk of relapse after treatment

More than 100 million humans around the world are infected with hepatitis C virus. The infection gives rise to chronic liver inflammation, which may result in reduced liver function, liver cirrhosis and liver cancer.

14 Mar 2014

Study shows effect of oral fungal yeast in inhibiting thrush

Scientists at Case Western Reserve School of Medicine and University Hospitals (UH) Case Medical Center have discovered how the beneficial fungal yeast, Pichia, holds at bay a harmful fungal yeast, Candida.

14 Mar 2014

Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

A protein that normally protects cells from environmental stresses has been shown to interact Marburg virus VP24, allowing the deadly Marburg virus to live longer and replicate better, according to a cell culture study led by scientists at the Icahn School of Medicine at Mount Sinai.

14 Mar 2014

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

TaiGen Biotechnology Company, Limited today announced that the Taiwan Food and Drug Administration has approved the new drug application (NDA) of Taigexyn (nemonoxacin) oral formulation (500 mg) for the treatment of community-acquired bacterial pneumonia (CAP). With this NDA approval, Taiwan is the first region to grant marketing approval to Taigexyn.

13 Mar 2014

New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research has found some compounds effective in blocking the proliferation of certain bacteria, raising hopes of a new class of drugs to combat antibiotic resistant infections

13 Mar 2014

Programs for heterosexuals who use drugs linked with subsequent lower rates of AIDS incidence

Although community network studies show that sexual relationships occur between members of "risk groups" -- men who have sex with other men (MSM), people who inject drugs (PWID), non-injection drug users (NIDU) -- and heterosexuals, researchers at New York University's Center for Drug Use and HIV Research (CDUHR) note that little research has been done to help explain how HIV epidemics and programs in one population affect others and how to reduce the risks of transmission.

13 Mar 2014

Notre Dame biologists awarded $23M research grant to prevent malaria and dengue fever

Notre Dame biologists Nicole Achee and Neil Lobo are leaders of an international $23 million research grant from the Bill & Melinda Gates Foundation. Their five-year project will generate the data required to show the effectiveness of a new paradigm in mosquito control -spatial repellency - for the prevention of two important mosquito-borne diseases: malaria and dengue fever.

13 Mar 2014

Disease/Infection News

CLL patients more prone to infections due to reduced number of antibodies

Dartmouth, Aeras to jointly conduct trial of DAR-901 vaccine against TB

China manages to halve TB prevalence in 20 years

Quail and chickens are likely sources of infection of H7N9 influenza virus to humans

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

Sequencing reveals genetic diversity in hospital-acquired bacterium

AV drugs could help curb bacteria's growing resistance to antibiotic treatments

New research commissioned to create infection control strategy for AMR and antibiotic usage

Patients with both HIV and hepatitis C have 80% higher rates of serious liver disease

Study shows only 23% of seasonal and pandemic flu caused symptoms

L. reuteri Protectis reduces diarrhea, respiratory tract infections in healthy children

Honey helps fight antibiotic resistance, says study

Hepatitis C patients with ITPA gene variants exhibit lower risk of relapse after treatment

Study shows effect of oral fungal yeast in inhibiting thrush

Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

New research raises hopes of new class of drugs to combat antibiotic resistant infections

Programs for heterosexuals who use drugs linked with subsequent lower rates of AIDS incidence

Notre Dame biologists awarded $23M research grant to prevent malaria and dengue fever

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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