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Merck announces new data from ongoing C-WORTHY Study in HIV/HCV co-infected patients

Merck, known as MSD outside of the United States and Canada, today announced new data from HIV/HCV co-infected patients in the ongoing C-WORTHY Study, a Phase 2 clinical trial evaluating the efficacy and safety of Merck's all-oral, once-daily regimen combining MK-5172, an investigational hepatitis C virus (HCV) NS3/4A protease inhibitor, and MK-8742, an investigational HCV NS5A replication complex inhibitor.

5 Mar 2014

Haiti HIV program increases sexual health awareness and practices in women

New research from the University of Toronto shows that a little training can go a long way in a desperate situation.

5 Mar 2014

Stock-outs of ARV drugs in Central African Republic impact health of HIV-infected people

According to Pierre-Marie David of the University of Montreal's Faculty of Pharmacy, stock-outs of antiretroviral (ARV) drugs in recent years in the Central African Republic have had a dramatic impact on the health of HIV-infected people.

5 Mar 2014

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.

5 Mar 2014

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Cell phones have become our constant companions, and as a result, they are exposed to many bacteria and viruses. When we open a door, shake hands, use an ATM or dozens of other daily tasks, our hands come in contact with germs, and numerous studies have shown that a significant number of bacteria, such as the flu virus, staph, strep, E. coli, and salmonella, are transferred from our hands to our cell phones every time we pick them up.

5 Mar 2014

Researchers develop adjuvant which enhances effect of virus transduction

Lentiviruses, which belong to the family of retroviruses, are used as vectors to exchange genetic material in cells and can be used to replace a defective gene as defined by gene therapy.

5 Mar 2014

Novel HIV prevention products for women demonstrate safety in clinical studies

Two early clinical studies of novel HIV prevention products for women - the first combination antiretroviral (ARV) vaginal ring and a vaginal film - show the products to be safe and open the door to product improvements that could expand options for women-initiated prevention tools. The results of both studies were presented today at the 21st Conference on Retroviruses and Opportunistic Infections.

5 Mar 2014

Merck reports results from Phase 2b study of investigational house dust mite sublingual immunotherapy tablet

Merck, known as MSD outside the United States and Canada, today announced results from a Phase 2b study evaluating two doses of its investigational house dust mite sublingual immunotherapy tablet (MK-8237). The data were presented for the first time during a late-breaking oral session at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) in San Diego.

5 Mar 2014

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

The bacterium Staphylococcus aureus (S. aureus) is a common source of infections that occur after surgeries involving prosthetic joints and artificial heart valves. The grape-shaped microorganism adheres to medical equipment, and if it gets inside the body, it can cause a serious and even life-threatening illness called a Staph infection. The recent discovery of drug-resistant strains of S. aureus makes matters even worse.

5 Mar 2014

Study: Combination intervention completely eliminates HIV transmission

A computer model has created the most effective formula for reducing the spread of HIV among drug users in New York City over the next 25 years.

5 Mar 2014

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of €6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria.

4 Mar 2014

Study shows SuperMum campaign improves handwashing behaviour

An analysis of a unique “SuperMum” handwashing campaign shows for the first time that using emotional motivators, such as feelings of disgust and nurture, rather than health messages, can result in significant, long-lasting improvements in people’s handwashing behaviour, and could in turn help to reduce the risk of infectious diseases.

4 Mar 2014

New tool may hold key to personalized medicine applications in the future

ather than your average bowl of Lucky Charms, these are three-dimensional cell cultures generated by an exciting new digital microfluidics platform, the results of which have been published in Nature Communications this week by researchers at the University of Toronto.

4 Mar 2014

Loyola physician sheds light on common and painful viral infection, shingles

Shingles is a painful viral infection that affects almost one million people worldwide and 30 percent of Americans every year.

4 Mar 2014

Study: Self-administration of flu vaccines with microneedle patches may one day be feasible

The annual ritual of visiting a doctor's office or health clinic to receive a flu shot may soon be outdated, thanks to the findings of a new study published in the journal Vaccine.

4 Mar 2014

Study characterizes mechanisms of pathogenesis, transmission of bacteria that cause gonorrhea

Researchers have come a step closer to understanding how gonorrhea infections are transmitted. When Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, are exposed to seminal plasma, the liquid part of semen containing secretions from the male genital tract, they can more easily move and start to colonize.

4 Mar 2014

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

The first detailed results from AbbVie's pivotal phase III study, PEARL-III, were presented today as part of the 21st Conference on Retroviruses and Opportunistic Infections (CROI) press conference and will also be presented as a late-breaker at the conference on March 4.

4 Mar 2014

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it received regulatory approval to begin a Phase 2a clinical trial of ARC-520, its RNAi-based drug candidate for the treatment of chronic hepatitis B virus (HBV) infection.

4 Mar 2014

New findings point the way toward potentially more effective HIV vaccine

In an advance for HIV vaccine research, a scientific team has discovered how the immune system makes a powerful antibody that blocks HIV infection of cells by targeting a site on the virus called V1V2.

4 Mar 2014

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig's disease, a debilitating neurological disorder that robs people of their motor skills.

4 Mar 2014

Disease/Infection News

Merck announces new data from ongoing C-WORTHY Study in HIV/HCV co-infected patients

Haiti HIV program increases sexual health awareness and practices in women

Stock-outs of ARV drugs in Central African Republic impact health of HIV-infected people

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Researchers develop adjuvant which enhances effect of virus transduction

Novel HIV prevention products for women demonstrate safety in clinical studies

Merck reports results from Phase 2b study of investigational house dust mite sublingual immunotherapy tablet

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

Study: Combination intervention completely eliminates HIV transmission

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

Study shows SuperMum campaign improves handwashing behaviour

New tool may hold key to personalized medicine applications in the future

Loyola physician sheds light on common and painful viral infection, shingles

Study: Self-administration of flu vaccines with microneedle patches may one day be feasible

Study characterizes mechanisms of pathogenesis, transmission of bacteria that cause gonorrhea

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

New findings point the way toward potentially more effective HIV vaccine

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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