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Researchers shed new light on pain associated with bacterial infections

Components in the outer wall of bacteria directly activate pain sensors, triggering immediate pain and inflammatory responses. This finding by a multinational team of researchers led by Professor Karel Talavera (KU Leuven, Belgium) and Professor Félix Viana (Institute of Neuroscience, Spain) sheds new light on pain associated with bacterial infections and reveals a new target for drugs designed to treat them.

11 Feb 2014

Scientists identify factors that predict flu severity in patients

St. Jude Children's Research Hospital scientists have identified a signature immune response that might help doctors identify which newly diagnosed influenza patients are most likely to develop severe symptoms and suffer poor outcomes. The findings also help explain why infants and toddlers are at elevated risk for flu complications. The research appears in the upcoming issue of the American Journal of Respiratory and Critical Care Medicine.

10 Feb 2014

Sarepta Therapeutics reports positive safety results from AVI-7288 Phase I study

Sarepta Therapeutics, Inc., a developer of innovative RNA-based therapeutics, today announced positive safety results from a Phase I multiple ascending dose study of AVI-7288 in healthy volunteers.

10 Feb 2014

New study tracks spread of H5N1 variant in Egypt recently identified as major epicenter for virus

Since its first identification in Asia, highly pathogenic avian influenza-H5N1-has caused significant alarm in the scientific community. While the virus' primary target is birds-tens of millions have already died from it-it is capable of infecting mammals, including humans, causing serious illness and a frightening rate of mortality.

10 Feb 2014

Hot flashes, depression and anxiety affect thinking skills of midlife women with HIV

Hot flashes, depression, and most of all, anxiety, affect the thinking skills of midlife women with HIV, so screening for and treating their anxiety may be especially important in helping them function, according to a study just published online in Menopause, the journal of The North American Menopause Society (NAMS).

9 Feb 2014

Finding could lead to first effective vaccine against respiratory syncytial virus

Vanderbilt University scientists have contributed to a major finding, reported today in the journal Nature, which could lead to the first effective vaccine against respiratory syncytial virus (RSV), a significant cause of infant mortality.

9 Feb 2014

Rice, UTMB develop diagnostic test for cryptosporidiosis

Bioengineers at Rice University and the University of Texas Medical Branch (UTMB) at Galveston have developed a simple, highly sensitive and efficient test for the diarrheal disease cryptosporidiosis that could have great impact on global health.

7 Feb 2014

Study: Investigational drug effective in reducing mucormycosis infections

With very few treatment options available to fight deadly mucormycosis infections, a new Los Angeles Biomedical Research Institute (LA BioMed) study holds hope for adding to the arsenal of therapies physicians have to combat an increasingly common infection afflicting people with weakened immune systems.

7 Feb 2014

Scientists present evidence of correlation between migration patterns of salmon and magnetic field

A team of scientists last year presented evidence of a correlation between the migration patterns of ocean salmon and the Earth's magnetic field, suggesting it may help explain how the fish can navigate across thousands of miles of water to find their river of origin.

7 Feb 2014

TSRI scientists discover unusual protein that probably helps some bacteria evade immune response

A team led by scientists at The Scripps Research Institute (TSRI) has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target. Protein M, as it is called, probably helps some bacteria evade the immune response and establish long-term infections.

7 Feb 2014

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

A team of researchers, led by scientists at Case Western Reserve University, has developed a multifunctional nanoparticle that enables magnetic resonance imaging (MRI) to pinpoint blood vessel plaques caused by atherosclerosis.

7 Feb 2014

Study finds links between degree of urbanization and prevalence of parasites in wild house finches

Humans living in densely populated urban areas have a profound impact not only on their physical environment, but also on the health and fitness of native wildlife. For the first time, scientists have found a direct link between the degree of urbanization and the prevalence and severity of two distinct parasites in wild house finches.

6 Feb 2014

TSRI scientists design artificial proteins as a candidate vaccine against RSV

Scientists at The Scripps Research Institute (TSRI) have invented a new method for designing artificial proteins, and have used it to make key ingredients for a candidate vaccine against a dangerous virus, respiratory syncytial virus (RSV), a significant cause of infant mortality.

6 Feb 2014

Researchers design new vaccine for human-infecting respiratory syncytial virus

Vaccines are the safest, cheapest and most effective way to protect against infectious diseases. But to make a good one is still a challenge, and traditional approaches are now stretched to the limit while fatal diseases, like HIV and malaria, remain without vaccine.

6 Feb 2014

Chinese scientists confirm world’s first case of human infection with new avian influenza virus

Scientists from China report in The Lancet on the world’s first confirmed case of human infection with a new avian influenza A H10N8 virus in a 73-year-old woman who died from the infection.

6 Feb 2014

Fraunhofer USA receives FDA clearance for IND malaria TBV that targets Pfs25 antigen

Fraunhofer USA Center for Molecular Biotechnology (FhCMB) announced today that clearance was obtained from the U.S. Food and Drug Administration (FDA) for an investigational new drug (IND), Fraunhofer's plant-derived malaria transmission-blocking vaccine (TBV), which targets the Pfs25 antigen, to proceed into the clinic in a Phase 1 safety and immunogenicity study.

5 Feb 2014

Study shows similarities in pathogenesis of neurological diseases and HIV virus

A new study by George Washington University (GW) researcher Michael Bukrinsky, M.D., Ph.D., shows similarities in the pathogenesis of prion disease — misfolded proteins that can lead to neurological diseases — and the HIV virus.

5 Feb 2014

95% of adults die annually from vaccine preventable diseases

While adults make up 95 percent of those who die annually from vaccine preventable diseases, a new study from the University of Colorado School of Medicine shows their vaccination rates remain stubbornly low, representing a growing public health concern.

5 Feb 2014

HIV-positive men more likely to have safe sex when their mood improves, says study

Having a good week? It may lead to healthier choices. If you are a man with HIV, you may be more likely to use a condom during sex. In a new study, researchers at Columbia University's Mailman School of Public Health report that HIV-positive men whose moods improved in a given week were more likely to have safe sex than they would in a normal week.

5 Feb 2014

Alabama experts develop living document that includes new therapies for Hepatitis C virus

When treatment guidelines for a particular disease emerge, they are often published in a peer-reviewed medical journal, which can take up to three years. One University of Alabama at Birmingham infectious diseases expert recently helped develop new Hepatitis C virus (HCV) guidelines that can be updated and published as new data emerge and new therapies are approved.

5 Feb 2014

Disease/Infection News

Researchers shed new light on pain associated with bacterial infections

Scientists identify factors that predict flu severity in patients

Sarepta Therapeutics reports positive safety results from AVI-7288 Phase I study

New study tracks spread of H5N1 variant in Egypt recently identified as major epicenter for virus

Hot flashes, depression and anxiety affect thinking skills of midlife women with HIV

Finding could lead to first effective vaccine against respiratory syncytial virus

Rice, UTMB develop diagnostic test for cryptosporidiosis

Study: Investigational drug effective in reducing mucormycosis infections

Scientists present evidence of correlation between migration patterns of salmon and magnetic field

TSRI scientists discover unusual protein that probably helps some bacteria evade immune response

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

Study finds links between degree of urbanization and prevalence of parasites in wild house finches

TSRI scientists design artificial proteins as a candidate vaccine against RSV

Researchers design new vaccine for human-infecting respiratory syncytial virus

Chinese scientists confirm world’s first case of human infection with new avian influenza virus

Fraunhofer USA receives FDA clearance for IND malaria TBV that targets Pfs25 antigen

Study shows similarities in pathogenesis of neurological diseases and HIV virus

95% of adults die annually from vaccine preventable diseases

HIV-positive men more likely to have safe sex when their mood improves, says study

Alabama experts develop living document that includes new therapies for Hepatitis C virus

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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