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Medivir initiates phase IIa trial to evaluate efficacy of simeprevir combination therapy in HCV-infected patients

Medivir AB (STO:MVIR-B) (OMX: MVIR), announces the initiation of a phase IIa trial in chronic genotype 1 hepatitis C infected patients to evaluate the efficacy, safety and tolerability of a 12-week combination therapy of simeprevir, TMC647055 and JNJ56914845, a NS5A replication complex inhibitor.

12 Dec 2013

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

Researchers at the Icahn School of Medicine at Mount Sinai reported that a virulent new strain of influenza - the virus that causes the flu - appears to retain its ability to cause serious disease in humans even after it develops resistance to antiviral medications. The finding was included in a study that was published today in the journal Nature Communications.

12 Dec 2013

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

GlaxoSmithKline plc announced today that a peer-reviewed study issued online by the New England Journal of Medicine has reported that GSK's FluLaval® Quadrivalent reduced flu cases among children ages 3-8 by 55.4% overall and lowered the risk of developing moderate-to-serious flu illness by 73.1%.

12 Dec 2013

Probe mimics pathogen's amino acids, solving mystery behind Chlamydiae cell wall

Biochemical sleuthing by an Indiana University graduate student has ended a nearly 50-year-old search to find a megamolecule in bacterial cell walls commonly used as a target for antibiotics, but whose presence had never been identified in the bacterium responsible for the most commonly reported sexually transmitted disease in the United States.

12 Dec 2013

Study resolves 50-year 'chlamydial anomaly' using novel method

Researchers studying Chlamydia trachomatis bacteria, which cause the sexually transmitted infection chlamydia as well as infectious blindness, have confirmed that the bacteria contain-and, in fact, cannot function without-the common molecule peptidoglycan, a structural component found in the cell wall of many bacteria. This finding puts an end to years of uncertainty about whether Chlamydia bacteria, like almost all bacterial species, rely on peptidoglycan to reproduce and to maintain their shape and structure. In addition, the novel method the investigators used may be adapted to further examine the molecule's role in the structure and function of other bacteria.

12 Dec 2013

Scientists use new method to map response of every salmonella gene to conditions in human body

Scientists have used a new method to map the response of every salmonella gene to conditions in the human body, providing new insight into how the bacteria triggers infection.

12 Dec 2013

Women with HER2+ breast tumors who receive combination therapy unlikely to have cancer recur

In a new study, women with relatively small, HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted therapy following surgery or radiation therapy were very unlikely to have the cancer recur within a few years of treatment, investigators at Dana-Farber Cancer Institute and other research centers will report at the 2013 San Antonio Breast Cancer Symposium.

12 Dec 2013

HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

Stigma has been defined as a social opportunistic disease that attaches to many illnesses and increases morbidity and mortality rates. Stigma is the shame or disgrace attached to illnesses and diseases regarded as socially unacceptable.

11 Dec 2013

Results-Based Financing for Health can get 20% more health care with same funds

Countries and major donors are changing the way they finance maternal and child, malaria, tuberculosis and HIV/AIDS health programs in low-income countries to increase their impact.

11 Dec 2013

Detectable blood viral load increases prevalence of heart disease

HIV causes structural heart disease according to research presented at EuroEcho-Imaging 2013 by Dr Nieves Montoro from Madrid, Spain. The findings support the introduction of cardiovascular screening in all HIV patients, particularly those with a positive blood viral load.

11 Dec 2013

New antimicrobial coating prevents infections during cold winter months

With cold and flu season now in full swing, all-natural wellness provider Neutra Corp. (OTCBB: NTRR) is working quickly to deliver a revolutionary new antimicrobial coating that could soon prove to be the best defense against infections and viruses in the most notorious hotspot for the spread of these diseases: the classroom.

11 Dec 2013

New AquaLyse ionization technology prevents legionella and related disease outbreaks

With growing reports of Legionella and related Legionnaires' disease outbreaks in the USA, Canada and around the world, ProCare Water Treatment Inc. today announces its newest "AquaLyse® ICR-820" medical and commercial grade copper-silver ionization chamber cells.

11 Dec 2013

Duke University receives $2.9M grant to develop HIV vaccine candidate

Duke University has received a grant of up to $2.9 million from the Bill & Melinda Gates Foundation to produce an HIV vaccine candidate that will be tested in humans.

10 Dec 2013

CUSP project aims to reduce ventilator-associated pneumonia in hospitals

UHC announced its selection as a coordinating entity for a 3-year, $7.3 million contract from the Agency for Healthcare Research and Quality that has been awarded to the Johns Hopkins Armstrong Institute for Patient Safety and Quality to reduce ventilator-associated pneumonia in hospitals.

10 Dec 2013

Study finds large degree of genetic variation amongst M. tuberculosis in humans in Zambia

In Zambia, the incidence of all forms of human tuberculosis is estimated to be 444 per 100,000. There is also a high incidence of HIV and AIDS in the country. In the Kafue area, a high incidence of Mycobacterium bovis in both cattle and the Kafue lechwe antilope has been detected. This bacterium can infect humans and has been found in humans in the studied region of Namwala. Mycobacterium tuberculosis, which is the main cause of human tuberculosis, has also been detected in cattle in this region.

10 Dec 2013

Preparing for better management of Tamiflu-resistant influenza viruses

Researchers in Umeå and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Formas and VR, the research team will now continue their studies with a focus on alternative antiviral drugs.

10 Dec 2013

Restricting antibiotics use unlikely to stop spread of drug resistance in typhoid fever

Restricting the use of antibiotics is unlikely to stop the spread of drug resistance in typhoid fever, according to a study funded by the Wellcome Trust and published in the journal eLife.

10 Dec 2013

Study reveals that germ-free mice are susceptible to infection with foodborne pathogen

When it comes to fighting off pathogens like Listeria, your best allies may be the billions of microorganisms that line your gut, according to new research published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Dec 2013

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that COO and Head of R&D, Bruce Given, M.D., presented data on the Phase 1 clinical study of ARC-520, the company's clinical candidate for the treatment of chronic hepatitis B infection, at the HepDART 2013 conference being held on The Big Island, Hawaii.

9 Dec 2013

MUC5B protein plays key role in many lung-related ailments

An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis.

9 Dec 2013

Disease/Infection News

Medivir initiates phase IIa trial to evaluate efficacy of simeprevir combination therapy in HCV-infected patients

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

Probe mimics pathogen's amino acids, solving mystery behind Chlamydiae cell wall

Study resolves 50-year 'chlamydial anomaly' using novel method

Scientists use new method to map response of every salmonella gene to conditions in human body

Women with HER2+ breast tumors who receive combination therapy unlikely to have cancer recur

HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

Results-Based Financing for Health can get 20% more health care with same funds

Detectable blood viral load increases prevalence of heart disease

New antimicrobial coating prevents infections during cold winter months

New AquaLyse ionization technology prevents legionella and related disease outbreaks

Duke University receives $2.9M grant to develop HIV vaccine candidate

CUSP project aims to reduce ventilator-associated pneumonia in hospitals

Study finds large degree of genetic variation amongst M. tuberculosis in humans in Zambia

Preparing for better management of Tamiflu-resistant influenza viruses

Restricting antibiotics use unlikely to stop spread of drug resistance in typhoid fever

Study reveals that germ-free mice are susceptible to infection with foodborne pathogen

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

MUC5B protein plays key role in many lung-related ailments

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