Disease/Infection News

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Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Cholera bacteria, and other types of bacteria that cause diarrheal diseases, infect your intestines where they release AB5 protein toxins – that is they have a single toxic A-subunit that is linked to a pentamer of B-subunits that act as the delivery vehicle to transport the A-subunit into the cells.

8 Sep 2014

Restarting infliximab therapy after drug holiday is safe for patients with IBD

Restarting infliximab therapy after a drug holiday is safe and effective for patients with inflammatory bowel disease (IBD), according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

8 Sep 2014

Researchers receive $23.8 million from CMS to improve HIV prevention and care

Researchers at the George Washington University (GW) were awarded a grant estimated to be funded at $23.8 million from the Centers for Medicare & Medicaid Services (CMS) to study a new model that aims to improve HIV prevention and care while lowering healthcare costs.

8 Sep 2014

Penn State receives $1.8 million from PCORI to help patients with chronic kidney disease

Penn State College of Medicine has been awarded $1.8 million in research funding from the Patient-Centered Outcomes Research Institute (PCORI).

8 Sep 2014

Hospitals can improve flu vaccination rate among health care workers by using mandatory policy

Hospitals can greatly improve their flu vaccination rate among health care workers by using a mandatory employee vaccination policy, according to a Henry Ford Health System study.

8 Sep 2014

Diabetes epidemic may hamper global efforts to control TB, study reveals

The rapid increase in rates of type 2 diabetes in low- and middle-income countries where tuberculosis (TB) is endemic could hamper global efforts to control and eliminate TB, according to a new three-part Series about TB and diabetes, published in The Lancet Diabetes & Endocrinology.

8 Sep 2014

Antibiotic stewardship programs reduce hospital readmissions due to infection

Antibiotic stewardship programs, which promote the appropriate use of antibiotics in hospitals and other healthcare centers, not only lead to reduction in antibiotic use with reduced adverse events, but also lead to significant savings.

8 Sep 2014

Middle ear infections can be triggered by viral infection in nose, say researchers

Middle ear infections, which affect more than 85 percent of children under the age of 3, can be triggered by a viral infection in the nose rather than solely by a bacterial infection, according to researchers at Wake Forest Baptist Medical Center.

6 Sep 2014

Peramivir drug safe, effective at alleviating influenza symptoms

An analysis of phase 2 and phase 3 clinical trials shows that a single injected dose of the neuraminidase inhibitor (NAI) peramivir is safe and effective at alleviating influenza symptoms, including fever and viral shedding, when administered within 48 hours of the onset of symptoms.

6 Sep 2014

Study: Innovative approaches required to decrease HIV transmission among Russian

Results of a new study conducted in St. Petersburg, Russia, show that decreasing HIV transmission among Russian HIV-infected drinkers will require creative and innovative approaches.

5 Sep 2014

Researchers investigating new ways to identify drugs against Ebola virus infection

Researchers from the University of Liverpool in collaboration with Public Health England have been investigating new ways to identify drugs that could be used to treat Ebola virus infection.

5 Sep 2014

Avian influenza A H3N8 virus poses threat to humans

A study led by St. Jude Children's Research Hospital scientists found the avian influenza A H3N8 virus that killed harbor seals along the New England coast can spread through respiratory droplets and poses a threat to humans.

5 Sep 2014

FDA provides QIDP designation to Debiopharm’s Debio 1450 for treatment of ABSSSI

Debiopharm Group™(Debiopharm), a Swiss-based global biopharmaceutical company developing prescription drugs that target unmet medical needs including anti-infective and oncology therapeutics as well as companion diagnostics, today announced that the US Food and Drug Administration (FDA) has designated its anti-infectious agent Debio 1450 as a Qualified Infectious Disease Product (QIDP) for the treatment of acute bacterial skin and skin structure infections (ABSSSI).

4 Sep 2014

Leading experts propose new treatment guidelines for chronic Lyme disease

Current treatments for Lyme disease, particularly chronic forms of the disease, are inadequate, according to a new treatment guideline written by a group of leading experts.

4 Sep 2014

Case Western Reserve scientists discover leaky gut as source of non-AIDS complications

Human immunodeficiency virus (HIV) infection is no longer a fatal condition, thanks to newer medications inhibiting the retrovirus, but a puzzling phenomenon has surfaced among these patients — non-AIDS complications. Scientists at Case Western Reserve University School of Medicine have resolved the mystery with their discovery of the leaky gut as the offender.

4 Sep 2014

Novira completes Phase 1a clinical study of NVR-1221 for treatment of HBV infection

Novira Therapeutics, Inc., a privately held biopharmaceutical company developing novel therapies for curative treatment of chronic hepatitis B virus (HBV) infection, today announced successful completion of a Phase 1a clinical study of NVR-1221.

4 Sep 2014

Findings may help develop biomarkers to identify HIV patients at risk of dementia

Since the introduction of the combination anti-retroviral therapy (cART) in the mid-90s, the life expectancy of HIV patients has significantly improved. As a result, long-term complications are becoming more relevant: almost every second HIV patient is affected by neurocognitive disorders, which can lead to dementia.

4 Sep 2014

New antibody in HIV-infected person binds to virus

An NIH-led team of scientists has discovered a new vulnerability in the armor of HIV that a vaccine, other preventive regimen or treatment could exploit.

4 Sep 2014

Football players are found to be carriers of sickle cell trait later in life

From 2000 to 2014, nine collegiate football players unexpectedly collapsed and died during training. The cause? Muscle breakdown leading to organ failure.

4 Sep 2014

3 billion people worldwide at risk of early death due to household air pollution

Household air pollution, caused by the use of plant-based or coal fuel for cooking, heating, and lighting, is putting nearly three billion people worldwide at risk of ill health and early death, according to a new Commission, published in The Lancet Respiratory Medicine journal.

4 Sep 2014

Disease/Infection News

Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Restarting infliximab therapy after drug holiday is safe for patients with IBD

Researchers receive $23.8 million from CMS to improve HIV prevention and care

Penn State receives $1.8 million from PCORI to help patients with chronic kidney disease

Hospitals can improve flu vaccination rate among health care workers by using mandatory policy

Diabetes epidemic may hamper global efforts to control TB, study reveals

Antibiotic stewardship programs reduce hospital readmissions due to infection

Middle ear infections can be triggered by viral infection in nose, say researchers

Peramivir drug safe, effective at alleviating influenza symptoms

Study: Innovative approaches required to decrease HIV transmission among Russian

Researchers investigating new ways to identify drugs against Ebola virus infection

Avian influenza A H3N8 virus poses threat to humans

FDA provides QIDP designation to Debiopharm’s Debio 1450 for treatment of ABSSSI

Leading experts propose new treatment guidelines for chronic Lyme disease

Case Western Reserve scientists discover leaky gut as source of non-AIDS complications

Novira completes Phase 1a clinical study of NVR-1221 for treatment of HBV infection

Findings may help develop biomarkers to identify HIV patients at risk of dementia

New antibody in HIV-infected person binds to virus

Football players are found to be carriers of sickle cell trait later in life

3 billion people worldwide at risk of early death due to household air pollution

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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