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Nonabsorbable antibiotics effective in eradicating CRE colonization

Orally administered, nonabsorbable antibiotics were effective in eradicating carbapenem-resistant Enterobacteriaceae (CRE) colonization, according to a new study published in the December issue of the American Journal of Infection Control, a publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

27 Nov 2013

Study shows most corneal transplants have remarkable longevity regardless of donor age

Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, and corneas from donors over 71 perform slightly less well but still remain healthy for most transplant recipients, according to a study funded by the National Eye Institute (NEI) and led by the UC Davis Health System Eye Center and the University of Cincinnati Eye Institut

27 Nov 2013

Researchers show how unusual properties of A3G protein help fight HIV infection

A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G.

27 Nov 2013

H1N1 virus killed more people globally than originally believed, confirms study

A research team consisting of more than 60 collaborators in 26 countries has estimated the global death toll from the 2009 outbreak of the H1N1 virus to be 10 times higher than the World Health Organization's count, which was based on laboratory-confirmed cases of this flu. The study, which appears online in PLOS Medicine, suggests that the pandemic virus caused up to 203,000 respiratory deaths around the world.

27 Nov 2013

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, MD, have found that restoring the normal, helpful bacteria of the gut and intestines may treat patients suffering from recurrent Clostridium difficile infections. Transplanting fecal matter of healthy donors into patients with recurrent C. difficile infection appears to restore normal bacterial composition and resolve infection.

27 Nov 2013

Participating in photovoice empowers women living with HIV to realize their strengths

Having human immunodeficiency virus, the virus that causes AIDS, can create many challenges for individuals physically, socially and emotionally. A University of Missouri researcher found that participating in photovoice, a process by which individuals document their lives by taking pictures, empowered women living with HIV to realize their strengths in the midst of their struggles.

27 Nov 2013

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 study for ISIS-GSK3Rx and earned a $3 million milestone payment from GlaxoSmithKline.

27 Nov 2013

Bioxodes completes seed funding round to bring Ir-CPI product into pre-clinical development

Bioxodes SA, a company developing products derived from natural sources, has completed a EUR 2.6 million (USD 3.5 million) first seed funding round with a consortium of business angels and Belgian investment funds. EUR 1.6 million is from the European Regional Development Fund and the Walloon Region in Belgium via the Retech program for Research and Technology. It will be used to bring the company’s lead product Ir-CPI into pre-clinical development over the next 18 months.

27 Nov 2013

Merck announces approval of NOXAFIL delayed-release tablets by FDA

Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved NOXAFIL® (posaconazole) 100 mg delayed-release tablets.

27 Nov 2013

Inhibitor compounds could form basis of new treatments for such diseases as MRSA, anthrax

Inhibitor compounds developed by UC Irvine structural biologists and Northwestern University chemists have been shown to bolster the ability of antibiotics to treat deadly bacterial diseases such as MRSA and anthrax.

27 Nov 2013

EU-funded project develops new type of vaccine to tackle HIV virus infection

AIDS research has attempted many strategies to tackle the HIV virus infection. Now, a new type of vaccine developed within an EU-funded project, called EuroNeut-41, is based on one of the envelope proteins of the HIV virus, called the gp41 protein. What makes it interesting it that it is directly responsible for the fusion of the HIV virus into human cells. By integrating the gp41 protein into the vaccine, researchers try to trigger the production of antibodies that would block the entrance of HIV into human cells

27 Nov 2013

MSF launches film series to counterbalance rhetoric presenting the fight against HIV/AIDS as almost won

The fight against HIV/AIDS has been hailed as one of the most successful public health projects in human history, but teams from the international medical humanitarian organisation Médecins Sans Frontières/Doctors Without Borders (MSF) see the revolution as unfulfilled for millions of people excluded from treatment.

26 Nov 2013

HPV vaccine coverage among teens still remains low than other recommended vaccinations

Barriers to human papillomavirus (HPV) vaccination among adolescents in the U.S. range from financial concerns and parental attitudes to social influences and concerns about the vaccination's effect on sexual behavior, according to a review of the available medical literature published by JAMA Pediatrics, a JAMA Network publication.

26 Nov 2013

HIV patients face higher risk of virologic failure than previously thought

People with human immunodeficiency virus (HIV) run a higher risk of virologic failure than previously thought, even when their number of RNA copies of the retrovirus per millilitre of blood is slightly above the detection threshold, according to a study by Claudie Laprise at the University of Montreal's Department of Social and Preventative Medicine.

26 Nov 2013

New concept outlines steps to tackle neglected tropical diseases, expedite poverty reduction efforts

A new concept and policy framework published in PLOS NTDs outlines concrete steps for the global development community as it works to synthesize health goals with economic, environmental and social priorities.

26 Nov 2013

EMA grants accelerated assessment to Boehringer Ingelheim's Faldaprevir compound

The application for European marketing authorisation of faldaprevir, a potent second generation oral protease inhibitor, has been fully validated and granted accelerated assessment by the European Medicines Agency (EMA).

26 Nov 2013

Researchers identify key immune cells that turn body's defenders against invading golden staph

When golden staph enters our skin it can identify the key immune cells and 'nuke' our body's immune response.

26 Nov 2013

Pediatrician analyzes management of the 2009 influenza A crisis

With autumn just around the corner and a new flu strain lying in wait for us, the presentation of a study analysing the management of the 2009 influenza A crisis could not, if anything, be better timed.

26 Nov 2013

Garlic compounds can kill foodborne pathogen present in infant formula powder

Garlic may be bad for your breath, but it's good for your baby, according to a new study from the University of British Columbia.

26 Nov 2013

Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it recently filed an application for approval to begin a phase 2a clinical trial of its RNAi-based therapeutic candidate, ARC-520, for the potential treatment of chronic hepatitis B virus infection.

25 Nov 2013

Disease/Infection News

Nonabsorbable antibiotics effective in eradicating CRE colonization

Study shows most corneal transplants have remarkable longevity regardless of donor age

Researchers show how unusual properties of A3G protein help fight HIV infection

H1N1 virus killed more people globally than originally believed, confirms study

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Participating in photovoice empowers women living with HIV to realize their strengths

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Bioxodes completes seed funding round to bring Ir-CPI product into pre-clinical development

Merck announces approval of NOXAFIL delayed-release tablets by FDA

Inhibitor compounds could form basis of new treatments for such diseases as MRSA, anthrax

EU-funded project develops new type of vaccine to tackle HIV virus infection

MSF launches film series to counterbalance rhetoric presenting the fight against HIV/AIDS as almost won

HPV vaccine coverage among teens still remains low than other recommended vaccinations

HIV patients face higher risk of virologic failure than previously thought

New concept outlines steps to tackle neglected tropical diseases, expedite poverty reduction efforts

EMA grants accelerated assessment to Boehringer Ingelheim's Faldaprevir compound

Researchers identify key immune cells that turn body's defenders against invading golden staph

Pediatrician analyzes management of the 2009 influenza A crisis

Garlic compounds can kill foodborne pathogen present in infant formula powder

Arrowhead seeks approval to start ARC-520 phase 2a trial for chronic hepatitis B infection

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