Disease/Infection News

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Semi-soft vaginal suppository provides drug-delivery vehicle to prevent spread of HIV

A unique method for delivering compounds that could positively impact the global battle against HIV and AIDS may be possible, thanks to researchers in Penn State's College of Agricultural Sciences.

30 Aug 2014

Blend of three monoclonal antibodies can protect monkeys against Ebola virus, says UTMB researcher

A leading U.S. Ebola researcher from the University of Texas Medical Branch at Galveston has gone on record stating that a blend of three monoclonal antibodies can completely protect monkeys against a lethal dose of Ebola virus up to 5 days after infection, at a time when the disease is severe.

30 Aug 2014

New paper highlights ways to improve outcomes of Ebola virus infection

The largest-ever Ebola virus disease outbreak is ravaging West Africa, but with more personnel, basic monitoring, and supportive treatment, many of the sickest patients with Ebola virus disease do not need to die, note the authors of a new paper published ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

30 Aug 2014

Gene therapy may offer significant advantages in prevention of botulism exposure

The current method to treat acute toxin poisoning is to inject antibodies, commonly produced in animals, to neutralize the toxin. But this method has challenges ranging from safety to difficulties in developing, producing and maintaining the anti-serums in large quantities.

30 Aug 2014

Researchers make surprising discoveries about the body's early responses to HIV infection

Researchers at UC Davis have made some surprising discoveries about the body's initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β).

30 Aug 2014

Researchers receive encouraging results from two historic pediatric HIV vaccine trials

Applying the benefit of hindsight, researchers at Duke Medicine have reanalyzed the findings of two historic pediatric HIV vaccine trials with encouraging results. The vaccines had in fact triggered an antibody response -- now known to be associated with protection in adults -- that was previously unrecognized in the infants studied in the 1990s.

29 Aug 2014

Researchers reveal transmission rate of MERS coronavirus

The MERS coronavirus has caused disease outbreaks across the Arabian Peninsula and spread to Europe several times. The severe pneumonia virus has claimed the lives of several hundred people since its discovery in 2012.

29 Aug 2014

Solid-head power toothbrushes retain less bacteria than hollow-head toothbrushes

Solid-head power toothbrushes retain less bacteria compared to hollow-head toothbrushes, according to researchers at The University of Texas Health Science Center at Houston School of Dentistry.

29 Aug 2014

Rice University researchers confirm potent synthesis of natural tetracycline

A fortuitous collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic.

29 Aug 2014

Improving education about risky food handling behaviors may reduce foodborne illness

Improving education about risky food handling behaviors would reduce the amount of foodborne illness and help improve food security around the world, according to Kansas State University research.

29 Aug 2014

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

A candidate Ebola vaccine could be given to healthy volunteers in the UK, The Gambia and Mali as early as September, as part of an series of safety trials of potential vaccines aimed at preventing the disease that has killed more than 1,400 people in the current outbreak in West Africa.

29 Aug 2014

Vaccine for Chagas disease expected to be available within the next three years

The medical development has been tested in animal models, where it was observed that the disease stopped in 80 percent of cases; physicians expect similar results from a human control group.

29 Aug 2014

NIH to start initial human testing of investigational Ebola vaccine next week

Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

29 Aug 2014

New treatment fights respiratory syncytial virus

The New England Journal of Medicine published research results on Aug. 21 from a clinical trial of a drug shown to safely reduce the viral load and clinical illness of healthy adult volunteers intranasally infected with respiratory syncytial virus (RSV).

29 Aug 2014

Researchers develop potential antibody therapy for Sudan ebolavirus

Researchers from Albert Einstein College of Medicine of Yeshiva University and other institutions have developed a potential antibody therapy for Sudan ebolavirus (SUDV), one of the two most lethal strains of Ebola.

29 Aug 2014

Yale University researchers identify bacterial culprits that drive IBD

Yale University researchers have identified a handful of bacterial culprits that may drive inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis, using patients' own intestinal immune responses as a guide.

29 Aug 2014

Respiratory infection control measures being adopted for Ebola patients are unnecessary and may heighten public panic

Respiratory infection control measures – which have been adopted by most health agencies to deal with the Ebola epidemic in west Africa – are unnecessary, and may heighten panic and fear among the public, according to the authors of a new letter, published in The Lancet, and written by Professor Jose M. Martin-Moreno from the University of Valencia in Spain, and colleagues.

28 Aug 2014

Researchers report possible therapy that could help treat patients infected with SUDV

Ebola is a rare, but deadly disease that exists as five strains, none of which have approved therapies.

28 Aug 2014

Contaminated blood cultures can serve as diagnostic predictor for more targeted antibiotics

Some 30 percent of all positive hospital blood culture samples are discarded every day because they're "contaminated" - they reflect the presence of skin germs instead of specific disease-causing bacteria.

28 Aug 2014

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body.

28 Aug 2014

Disease/Infection News

Semi-soft vaginal suppository provides drug-delivery vehicle to prevent spread of HIV

Blend of three monoclonal antibodies can protect monkeys against Ebola virus, says UTMB researcher

New paper highlights ways to improve outcomes of Ebola virus infection

Gene therapy may offer significant advantages in prevention of botulism exposure

Researchers make surprising discoveries about the body's early responses to HIV infection

Researchers receive encouraging results from two historic pediatric HIV vaccine trials

Researchers reveal transmission rate of MERS coronavirus

Solid-head power toothbrushes retain less bacteria than hollow-head toothbrushes

Rice University researchers confirm potent synthesis of natural tetracycline

Improving education about risky food handling behaviors may reduce foodborne illness

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

Vaccine for Chagas disease expected to be available within the next three years

NIH to start initial human testing of investigational Ebola vaccine next week

New treatment fights respiratory syncytial virus

Researchers develop potential antibody therapy for Sudan ebolavirus

Yale University researchers identify bacterial culprits that drive IBD

Respiratory infection control measures being adopted for Ebola patients are unnecessary and may heighten public panic

Researchers report possible therapy that could help treat patients infected with SUDV

Contaminated blood cultures can serve as diagnostic predictor for more targeted antibiotics

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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