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Researchers show for first time how influenza A viruses infect respiratory cells

Researchers at the University of California, San Diego School of Medicine have shown for the first time how influenza A viruses snip through a protective mucus net to both infect respiratory cells and later cut their way out to infect other cells.

25 Nov 2013

Researchers identify immune cell protein that sets off body's initial response against viral infection

A Massachusetts General Hospital-led research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. The report that will be published in an upcoming issue of Nature Immunology and is receiving early online release describes finding that a protein called GEF-H1 is essential to the ability of macrophages - major contributors to the innate immune system - to respond to viral infections like influenza.

25 Nov 2013

CHMP recommends approval of Otsuka's Deltyba for pulmonary multidrug-resistant tuberculosis

Otsuka Pharmaceutical Co., Ltd. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended approval of Deltyba (delamanid) in combination with a WHO recommended optimized background regimen for the treatment of pulmonary multidrug-resistant tuberculosis (MDR-TB). The CHMP opinion will help form the basis for a European Commission decision expected early next year.

25 Nov 2013

UCSF investigator receives $89 M grant to research on anal cancer in people with HIV

A UC San Francisco investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.

25 Nov 2013

Research reveals that HPV infection is associated with higher subsequent risk of HIV infection

A study of 2,519 Kenyan men conducted by researchers at the University of North Carolina revealed that infection with the human papillomavirus (HPV) was associated with a higher subsequent risk of infection with HIV, a precursor to AIDS.

25 Nov 2013

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Janssen Therapeutics, Division of Janssen Products, LP, announced today the U.S. Food and Drug Administration has approved OLYSIO (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.

23 Nov 2013

New bill offers hope to HIV patients on transplant waiting lists

A bill scheduled to be signed into law today by President Obama reverses the longtime ban on letting HIV-infected people donate their organs for transplantation after death, a move that offers hope to thousands of HIV patients on transplant waiting lists.

22 Nov 2013

Vaccination campaign launched to prevent outbreaks of measles and polio in Philippines

WHO and the Philippine Department of Health have launched a vaccination campaign to prevent outbreaks of measles and polio among survivors of Typhoon Haiyan (Yolanda).

22 Nov 2013

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

During Antibiotic Awareness Week (18-24 November) NPS MedicineWise is urging health professionals to use vaccinations as one important way to limit Australia’s use of antibiotics.

22 Nov 2013

Incidence of oropharyngeal cancer on the rise

NCI scientists report that the incidence of oropharyngeal cancer significantly increased during the period 1983-2002 among people in countries that are economically developed.

22 Nov 2013

New documentary reveals how antiretroviral therapy transformed lives of HIV people in Africa

A new documentary produced by the University of East Anglia reveals how the lives of people with HIV in Africa have been transformed by antiretroviral therapy and highlights the crucial need for continued funding of the lifesaving treatment.

22 Nov 2013

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

Having high knowledge about HIV and engaging in risky sexual activity do not make high-school-aged teens more likely to get tested for HIV. Those are the findings of a new study by researchers at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University.

22 Nov 2013

Communicating with partners about parenting and HIV helps young people

A team from Royal Holloway University and St. Mary's Hospital, London, interviewed young people aged 18-23 who had transmitted HIV from their mothers - known as 'perinatally acquired HIV' (PAH). Previously most of these children would have died in childhood, but medication in the UK, means they are surviving into early adulthood.

22 Nov 2013

Younger people with HIV feel more isolated and stressed than older people

Case Western Reserve University researchers were surprised to learn that people younger than 50 years old with HIV feel more isolated and stressed than older people with the disease. They expected their study to reveal just the opposite.

21 Nov 2013

Bangladesh outperforms Asian neighbours despite low spending on health care

Exceptional improvements in the survival of infants and children under 5 years of age, life expectancy, immunisation coverage, and tuberculosis control in Bangladesh are part of a remarkable success story for health in the South Asian country, according to a major new Series published in The Lancet. This is despite low spending on health care, a weak health system, and widespread poverty.

21 Nov 2013

New method uses lab-on-a-chip device and cell phone to determine concentration of molecules

In developing nations, rural areas, and even one's own home, limited access to expensive equipment and trained medical professionals can impede the diagnosis and treatment of disease.

21 Nov 2013

Vaccinating kids against rotavirus may also reduce risk of seizures

A new study suggests an additional-and somewhat surprising-potential benefit of vaccinating children against rotavirus, a common cause of diarrhea and vomiting. Besides protecting kids from intestinal illness caused by rotavirus, immunization may also reduce the risk of related seizures, according to findings published in Clinical Infectious Diseases and available online.

21 Nov 2013

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Inovio Pharmaceuticals, Inc. announced today that preclinical testing of a DNA synthetic vaccine for the virulent Middle East Respiratory Syndrome coronavirus (MERS) induced robust and durable immune responses, demonstrating the potential for a SynCon DNA vaccine to prevent and treat this deadly virus.

20 Nov 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

TSRI researchers solve structure of key protein in deadly, but little known virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses. Researchers at The Scripps Research Institute (TSRI) have now solved the structure of a key protein in the Nipah virus, which could pave the way for the development of a much-needed antiviral drug.

20 Nov 2013

Disease/Infection News

Researchers show for first time how influenza A viruses infect respiratory cells

Researchers identify immune cell protein that sets off body's initial response against viral infection

CHMP recommends approval of Otsuka's Deltyba for pulmonary multidrug-resistant tuberculosis

UCSF investigator receives $89 M grant to research on anal cancer in people with HIV

Research reveals that HPV infection is associated with higher subsequent risk of HIV infection

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

New bill offers hope to HIV patients on transplant waiting lists

Vaccination campaign launched to prevent outbreaks of measles and polio in Philippines

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

Incidence of oropharyngeal cancer on the rise

New documentary reveals how antiretroviral therapy transformed lives of HIV people in Africa

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

Communicating with partners about parenting and HIV helps young people

Younger people with HIV feel more isolated and stressed than older people

Bangladesh outperforms Asian neighbours despite low spending on health care

New method uses lab-on-a-chip device and cell phone to determine concentration of molecules

Vaccinating kids against rotavirus may also reduce risk of seizures

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

TSRI researchers solve structure of key protein in deadly, but little known virus

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