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Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

Successful gene therapy is based on the effective delivery and maintained expression of healthy copies of a gene into tissues of individuals with a disease-associated genetic mutation.

16 Nov 2013

Scientists join patients to address Friedreich's Ataxia

The Spanish Federation of Ataxia (FEDAES)—in representation of the GENEFA Platform for a Friedreich's Ataxia cure—, the Babel Family association for biomedical research into Friedreich's Ataxia, the "Centro de Biología Molecular Severo Ochoa" (CMBSO), and the Institute for Research in Biomedicine (IRB Barcelona) have signed an agreement through which these patients' associations will fund, by means of donations, a 3-year research project addressing Friedreich's Ataxia.

16 Nov 2013

New Malaria Vaccine Technology Roadmap aims to identify second generation malaria vaccines

The world should aim to have vaccines which reduce malaria cases by 75%, and are capable of eliminating malaria, licensed by 2030, according to the updated 2013 "Malaria Vaccine Technology Roadmap", launched today.

15 Nov 2013

Designation of ISIS-GSK4Rx as a development candidate triggers milestone payment to Isis

Isis Pharmaceuticals, Inc. announced today that it has earned a $5 million milestone payment from GlaxoSmithKline related to the designation of ISIS-GSK4Rx as a development candidate. ISIS-GSK4Rx is an antisense drug designed to treat an undisclosed ocular disease.

15 Nov 2013

Rugby star partners with researchers to tackle motor neurone disease

A World Cup winning rugby star is joining forces with leading researchers in a new partnership to tackle motor neurone disease (MND).

15 Nov 2013

Two health care providers argue about making flu vaccination mandatory for health care workers

Should flu vaccines be mandatory for health care workers? That's the question raised this week in the British Medical Journal to two health care providers, including Penn Medicine's Amy J. Behrman, MD, in a "Head to Head" piece that argues both sides of the debate.

15 Nov 2013

New microbicide gel formulation shows promise for safe vaginal and rectal administration to prevent HIV

Researchers developed a first-of-its-kind microbicide gel formulation that shows promise for safe vaginal and rectal administration to prevent the sexual transmission of human immunodeficiency virus (HIV).

15 Nov 2013

Scientists discover new drug mechanism to reduce risk of infections

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered the exact mode of action by plerixafor, a drug commonly prescribed to stimulate immune responses in patients suffering from neutropenia, which causes them to become prone to oral, skin, genital infections and in worst cases, a fatal whole-body infection.

15 Nov 2013

Lower doses of antimalarial drug effective in reducing malaria transmission

Lower doses of the antimalarial drug primaquine are as effective as higher doses in reducing malaria transmission, according to a study published today in Lancet Infectious Diseases by London School of Hygiene & Tropical Medicine researchers.

15 Nov 2013

HIVMA's updated HIV care guidelines show doctors should focus on common health conditions

The HIV Medicine Association of the Infectious Diseases Society of America has updated its HIV care guidelines to reflect the fact that people with HIV are now living normal life spans, and their physicians need to focus on preventive care, including screening for high cholesterol, diabetes and osteoporosis.

15 Nov 2013

Small molecule compound shows significant success in controlling polyomaviruses

A team of scientists reports that a small molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened.

15 Nov 2013

AHF Lake Ida Healthcare Center offers specialized HIV/AIDS treatment

AIDS Healthcare Foundation is offering people living with HIV in South Florida a new opportunity for access to client-centered, specialized HIV/AIDS treatment and care through the AHF Lake Ida Healthcare Center. The clinic is operated under Pierre Dorsainvil, MD. Dr. Dorsainvil and his staff are fluent in English and Creole.

15 Nov 2013

Malaria No More honors Hillary Rodham Clinton with Global Leadership Award

In an inspiring awards dinner Monday night, Malaria No More presented Former United States Secretary of State and Former Senator from New York Hillary Rodham Clinton with the Global Leadership Award.

15 Nov 2013

Diagnosing influenza with rapid tests leads to more efficient care

When patients in the emergency department (ED) are diagnosed with influenza by means of a rapid test, they get fewer unnecessary antibiotics, are prescribed antiviral medications more frequently, and have fewer additional lab tests compared to patients diagnosed with influenza without testing, according to a new study. Published online in the Journal of the Pediatrics Infectious Diseases Society, the findings suggest that diagnosing influenza with a rapid diagnostic test leads to more appropriate, specific, and efficient care.

14 Nov 2013

Severe sepsis mortality rates decrease over the past 20 years

A recent study from Boston University School of Medicine and Boston Medical Center shows a significant decrease in severe sepsis mortality rates over the past 20 years. Looking at data from patients with severe sepsis enrolled in clinical trials, researchers found that in-hospital mortality rates decreased from 47 percent between 1991 and 1995 to 29 percent between 2006 and 2009, a time period when no new pharmacological treatments were developed for severe sepsis.

14 Nov 2013

Taiwan scientists confirm world’s first case of wild avian influenza A H6N1 virus in human

Scientists from Taiwan report on the world’s first confirmed case of human infection with a wild avian influenza A H6N1 virus in The Lancet Respiratory Medicine.

14 Nov 2013

Research findings could help decrease risk of dengue

A study by an international team of researchers led by Anna M. Stewart Ibarra, Ph.D., of the Center for Global Health and Translational Science at SUNY Upstate Medical University, has provided public health officials with information that will help decrease the risk of dengue, a life-threatening mosquito-borne viral disease that is now one of the fastest spreading tropical diseases globally.

14 Nov 2013

Groundbreaking study reveals novel approach to treat, eliminate MRSA infection

Recent work from University Distinguished Professor of Biology Kim Lewis promises to overcome one of the leading public health threats of our time. In a groundbreaking study published Wednesday in the journal Nature, Lewis' team presents a novel approach to treat and eliminate methicillin resistant staphylococcus aureus, or MRSA, a potent bacterium whose resistance to antibiotics has kept it one step ahead of researchers.

14 Nov 2013

Disease/Infection News

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

Scientists join patients to address Friedreich's Ataxia

New Malaria Vaccine Technology Roadmap aims to identify second generation malaria vaccines

Designation of ISIS-GSK4Rx as a development candidate triggers milestone payment to Isis

Rugby star partners with researchers to tackle motor neurone disease

Two health care providers argue about making flu vaccination mandatory for health care workers

New microbicide gel formulation shows promise for safe vaginal and rectal administration to prevent HIV

Scientists discover new drug mechanism to reduce risk of infections

Lower doses of antimalarial drug effective in reducing malaria transmission

HIVMA's updated HIV care guidelines show doctors should focus on common health conditions

Small molecule compound shows significant success in controlling polyomaviruses

AHF Lake Ida Healthcare Center offers specialized HIV/AIDS treatment

Malaria No More honors Hillary Rodham Clinton with Global Leadership Award

Diagnosing influenza with rapid tests leads to more efficient care

Severe sepsis mortality rates decrease over the past 20 years

Taiwan scientists confirm world’s first case of wild avian influenza A H6N1 virus in human

Research findings could help decrease risk of dengue

Groundbreaking study reveals novel approach to treat, eliminate MRSA infection

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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