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Gen-Probe receives FDA approval for APTIMA HPV assay

Gen-Probe Incorporated announced today that the US Food and Drug Administration (FDA) has approved its APTIMA HPV assay, an amplified nucleic acid test that detects high-risk strains of human papillomavirus (HPV) that are associated with cervical cancer and precancerous lesions.

31 Oct 2011

New antibiotic regimes may increase infections after specific surgical procedures

The introduction of new antibiotic regimes to tackle hospital-acquired infections, such as C. difficile, must take into account the possibility of increased infections following specific surgical procedures.

31 Oct 2011

Astex to present data on direct acting antiviral agents against HCV at 62nd AASLD meeting

Astex Pharmaceuticals, Inc., a pharmaceutical company dedicated to the discovery, development and commercialization of novel therapeutics, announced that it will present data on its novel, first-in-class direct acting antiviral agents (DAA) against Hepatitis C Virus (HCV) at the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in San Francisco, November 4-8, 2011.

31 Oct 2011

Fierce Vaccines highlights Inovio's VGX-3100 as one of 10 Promising Therapeutic Vaccines

Inovio Pharmaceuticals, Inc., which is advancing synthetic vaccines to fight cancers and infectious diseases, announced today that VGX-3100, its investigational SynCon vaccine for treating cervical dysplasia and cancer caused by human papillomavirus, was highlighted by Fierce Vaccines as one of 10 Promising Therapeutic Vaccines.

31 Oct 2011

New study describes 2010 norovirus outbreak involving several NBA teams

A new study describes a 2010 outbreak involving several NBA teams, the first known report of a norovirus outbreak in a professional sports association. Published in Clinical Infectious Diseases and available online, the study highlights unique circumstances for spreading this highly contagious virus among players and staff on and off the court.

31 Oct 2011

ZAMSTAR project reduces prevalence of tuberculosis by 22%

The results of a large-scale community-randomized trial presented at the 42nd World Conference on Lung Health in Lille, France today show that the Zambia-South Africa TB and AIDS Reduction (ZAMSTAR) project reduced the prevalence of tuberculosis by 22%.

31 Oct 2011

Cranberry juice far better than extracts at fighting urinary tract infections

With scientific evidence now supporting the age-old wisdom that cranberries, whether in sauce or as juice, prevent urinary tract infections, people have wondered if there was an element of the berry that, if extracted and condensed, perhaps in pill form, would be as effective as drinking the juice or eating cranberry sauce. A new study from researchers at Worcester Polytechnic Institute helps to answer that question.

29 Oct 2011

USAID celebrates 50 years of partnership with Kenya

This post in USAID's "IMPACTblog" -- the third of a four-part series on USAID's partnership with Kenya -- reports on how "USAID's health and population program ... works with partners in Kenya to bring health workers directly to the communities. These health workers provide information and care through HIV/AIDS and malaria programs, as well as work with community religious leaders to discuss family planning."

29 Oct 2011

NTDs among America's poor populations must be addressed

"The number of Americans living in poverty is at an all-time high, with close to 50 million people living below the poverty line," therefore "we desperately need a national dialogue about the unique afflictions of the bottom 50 million, paying particular attention to their neglected tropical diseases, which represent important stealth reasons trapping them in a vicious cycle of poverty," Peter Hotez, founding dean of the National School of Tropical Medicine at Baylor College of Medicine in Houston, writes in an Austin-American Statesman opinion piece.

29 Oct 2011

Not too early to consider funding for, distribution of malaria vaccine

In this Huffington Post opinion piece, Orin Levine, executive director of the International Vaccine Access Center of Johns Hopkins University, notes some of the parallels between the development of RTS,S, the experimental malaria vaccine currently being tested in Africa, and the polio vaccine, but he says "there are also some particularly disappointing ways in which the polio and malaria efforts could differ."

29 Oct 2011

Some experts question early release of RTS,S malaria vaccine trial data

Nature News reports on last week's announcement of preliminary results from a large clinical trial testing the efficacy of GlaxoSmithKline's (GSK) RTS,S malaria vaccine, writing that while media coverage of the announcement touted it as a "big breakthrough in the long campaign to create a malaria vaccine," "several leading vaccine researchers, who are critical of the unusual decision to publish partial trial data, argue that the results raise questions about whether the RTS,S/AS01 candidate vaccine can actually win approval."

29 Oct 2011

Seeking a broad scientific consensus on disease eradication

In a SciDev.Net letter to the editor, Rashid Zargar from the Centre of Research for Development at the University of Kashmir, responds to an editorial published by the news service last week in which editor David Dickson suggested that "focusing on the science and technology required to eliminate a disease, rather than just control it, can pay off."

29 Oct 2011

Global Health Technologies Coalition blog reports on health research projects in Kenya

In a post in the Global Health Technologies Coalition's "Breakthroughs" blog, GHTC's Kim Lufkin reports on her travels to Kenya this month "to visit global health research projects and see the impact on people in the country," writing, "Although we visited a range of projects, I was left with the lasting impression that much of this research is so close to producing new health tools that can lead to amazing innovations in public health," including "the first ever malaria vaccine, gels women can use to protect themselves from HIV, and new drugs for neglected diseases that affect the poorest of the poor."

29 Oct 2011

Researcher's compound disables bacteria instead of killing them

After 70 years, antibiotics are still the primary treatment for halting the spread of bacterial infections. But the prevalence of antibiotic resistance is now outpacing the rate of new drug discovery and approval. A microbiologist at the University of Wisconsin-Milwaukee (UWM) has discovered a different approach: Instead of killing the bacteria, why not disarm them, quashing disease without the worry of antibiotic resistance?

29 Oct 2011

Researchers identify compound that inhibits viral replication

Broad-spectrum antibiotics, which are active against a whole range of bacterial pathogens, have been on the market for a long time. Comparably versatile drugs to treat viral diseases, on the other hand, have remained elusive. Using a new approach, research teams led by Dr. Albrecht von Brunn of LMU Munich and Professor Christian Drosten from the University of Bonn have identified a compound that inhibits the replication of several different viruses, including the highly aggressive SARS virus that is responsible for severe acute respiratory syndrome.

29 Oct 2011

Scientists identify nicotinamidase enzyme as new drug target for Leishmaniasis

IRD scientist and their research partners recently identified the key role of nicotinamidase, an enzyme in the parasite Leishmania, essential for its survival but which does not exist in humans. The pathogen is incapable of developing in mammals In the absence of this enzyme. Specific targeting of this enzyme could lead to more effective ways of controlling this neglected tropical disease.

29 Oct 2011

NYUCN to study 'Test and Linkage to Care Among Injecting Drug Users Kenya'

New York University College of Nursing (NYUCN) received a five-year, $4,161,665.00 grant from the National Institute of Health's National Institute on Drug Abuse (NIH/NIDA) to research "Test and Linkage to Care Among Injecting Drug Users (TLC_IDU) Kenya."

29 Oct 2011

Number of polio cases in Pakistan exceeds total number reported in three other endemic countries, report says

According to a report published earlier this month in Virology Journal by a team at the bioinformatics laboratory of the Centre for Excellence in Molecular Biology (CEMB) in Lahore, Pakistan, that country is reporting more polio cases than Nigeria, India and Afghanistan -- the three other countries where the disease is endemic -- combined, SciDev.Net reports.

29 Oct 2011

NYUCN to study 'Combination HIV Prevention for Kenyan Youth'

New York University College of Nursing (NYUCN) received a four-year, $ 2.8M grant from the National Institute of Health's National Institute of Allergy and Infectious Diseases (NIH/NIAID) to study "Combination HIV Prevention for Kenyan Youth."

29 Oct 2011

NIH awards NYUCN $7.56M grant to study HIV risk among heterosexuals

New York University College of Nursing (NYUCN) received a five-year, $7.56 million grant from the National Institute on Drug Abuse (NIDA) at the National Institutes of Health (NIH) to evaluate the efficacy and cost-effectiveness of a peer-driven intervention to seek out heterosexuals at high risk for HIV in their communities, test them for HIV, and link them to care in a timely fashion if they are found to be HIV infected.

29 Oct 2011