Disease/Infection News

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Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Researchers raised concerns that some SARS-CoV-2 variants can escape detection by antigen tests.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Researchers demonstrated that E proteins of β-coronaviruses could restrict HIV-1 infection.

30 Mar 2022

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A new study shows that multiple variants of this virus may coinfect the same patient, using both genomic sequencing data and computational models.

30 Mar 2022

Lung abnormalities may remain detectable long after COVID-19 pneumonia

Some people recovering from COVID-19 pneumonia have CT evidence of damage to their lungs that persists a full year after the onset of symptoms, according to a new study published in the journal Radiology.

30 Mar 2022

Novel sensor could revolutionize COVID-19 virus testing

A COVID-19 sensor developed at Johns Hopkins University could revolutionize virus testing by adding accuracy and speed to a process that frustrated many during the pandemic.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes respiratory coronavirus disease 2019 (COVID-19) triggered an unprecedented public health emergency. Human mobility patterns were fundamental to the spread of SARS-CoV-2 globally. The situation is particularly acute in a country like Saudi Arabia, which has seen more than 750,000 cases and over 9,000 deaths as of March 30th, 2022.

29 Mar 2022

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

29 Mar 2022

A bioinformatics approach for detecting SARS-CoV-2 co-infections

Researchers discuss a novel bioinformatics-based method for the detection of SARS-CoV-2 co-infections with the Delta and Omicron variants.

29 Mar 2022

New test predicts sepsis well before blood clotting and organ failure

In a potential paradigm change for sepsis diagnostics, a new test predicted sepsis soon after infection in mice - well before blood clotting and organ failure - enabling early antibiotic treatment and markedly increased survival.

29 Mar 2022

COVID-19 pandemic had substantial effect on TB trends in the United States

In the United States, reported tuberculosis (TB) disease diagnoses fell 20% in 2020 and remained 13% lower in 2021 than TB disease diagnoses made prior to the COVID-19 pandemic, according to preliminary CDC data published today.

29 Mar 2022

Government provides new guidance for living with COVID

People at risk of serious illness from COVID-19, and eligible for treatments, will continue to get free tests to use if they develop symptoms, along with NHS and adult social care staff and those in other high-risk settings, Health and Social Care Secretary Sajid Javid announced today (Tuesday 29 March).

29 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

A new study assessed the molecular dynamics of potentially active natural phytochemicals to target the SARS-CoV-2 main protease.

29 Mar 2022

Trial shows effectiveness of new classes of dual active ingredient insecticidal nets against malaria

IVCC welcomes the publication in The Lancet of the 24-month results of an epidemiological trial in Tanzania, conducted by the London School of Hygiene and Tropical Medicine in partnership with the National Institute for Medical Research, Kilimanjaro Christian Medical University College, and the University of Ottawa, to assess the public health value of two dual active ingredient nets compared to standard LLINs containing pyrethroids only.

29 Mar 2022

Disease/Infection News

Antiviral functions of interferon regulatory factors during human coronavirus infection

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Study describes the identification of a SARS-CoV-2 variant that escapes detection by antigen tests

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

Lung abnormalities may remain detectable long after COVID-19 pneumonia

Novel sensor could revolutionize COVID-19 virus testing

A ferritin nanoparticle candidate vaccine for COVID

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

A bioinformatics approach for detecting SARS-CoV-2 co-infections

New test predicts sepsis well before blood clotting and organ failure

COVID-19 pandemic had substantial effect on TB trends in the United States

Government provides new guidance for living with COVID

The different actions of CBD in SARS-CoV-2 infection

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

Trial shows effectiveness of new classes of dual active ingredient insecticidal nets against malaria

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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