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The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

A new study, available on the arXiv* server, proposes a simple dynamic model for estimating the relative contagiousness of two variants of SARS-CoV-2, namely Alpha and Delta. Furthermore, it demonstrates how to compute the effective reproduction number for a new variant without contemporaneous sequencing results. This is important to assess the state of the pandemic in real-time.

20 Feb 2022

Full schedule of CoronaVac vaccine shown to be highly effective in children

A recent study on vaccine effectiveness showed that a complete primary immunization with CoronaVac effectively protects against severe coronavirus disease 2019 (COVID-19) for children and adolescents between 6 and 16 years of age – consistent with the results from phase 2 clinical trials. The paper is currently available on the Preprints with The Lancet* server while it undergoes peer review.

20 Feb 2022

Benchmarking models of SARS-CoV-2 transmission through aerosols and droplets

A new study generated a consolidated set of parameters involving the exhalation of particles.

20 Feb 2022

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

A new study focuses on understanding the factors associated with the ability of the Omicron variant to infect a wide range of age groups.

20 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The emergence of the SARS-CoV-2 Delta and Omicron variants caused severe disease and hospitalizations among children and adolescents.

20 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

New combination of antiviral drugs fails to improve outcomes in hospitalized patients with influenza

A new combination of antiviral drugs did not improve clinical outcomes in hospitalized patients with severe influenza, according results from a recent clinical trial published in The Lancet Infectious Diseases.

18 Feb 2022

Omicron outbreak in an indoor convention in New York

A recent report published by the CDC, USA, has demonstrated one of the earliest outbreaks of omicron infection in the US.

18 Feb 2022

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Researchers conducted a prospective cohort study to assess the level and durability of protection offered by two doses of COVID-19 vaccine against SARS-CoV-2 infection in participants with no history of a previous infection.

18 Feb 2022

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Two weeks makes a big difference in treating the animal version of HIV and latent tuberculosis, researchers from Texas Biomedical Research Institute, Southwest National Primate Research Center and colleagues report this month in the Journal of Clinical Investigation.

18 Feb 2022

Research provides a stronger connection between autoantibody formation and clotting in COVID-19

Scientists have discovered that "rogue" antibodies found circulating in the blood of COVID-19 patients have the potential to cause cells to lose their resistance to clotting.

18 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

In a new study, researchers evaluated the efficacy and safety of nirmatrelvir in mild to moderate COVID-19 patients who were at high risk of severe COVID-19 disease.

18 Feb 2022

VA researchers shine light on the dangerous mental health consequences of COVID-19

The most menacing fallout from COVID-19 often shows itself only after the initial "acute" infection passes. A team of VA researchers has been shining a light on various dangerous and enduring consequences that can arise following the initial COVID bout. These COVID complications include mental health disorders.

18 Feb 2022

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

Researchers evaluated the neutralizing capacity of the clinically approved mAbs against the SARS-CoV-2 Omicron BA.2 variant.

18 Feb 2022

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Researchers conducted a retrospective cohort study to assess the rate of SARS-CoV-2 reinfection in patients who had recovered from COVID-19.

18 Feb 2022

Disease/Infection News

The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

Full schedule of CoronaVac vaccine shown to be highly effective in children

Benchmarking models of SARS-CoV-2 transmission through aerosols and droplets

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

N-glycosylation blockers reduce SARS-CoV-2 infection

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The impact of SARS-CoV-2 on lipids

New combination of antiviral drugs fails to improve outcomes in hospitalized patients with influenza

Omicron outbreak in an indoor convention in New York

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Research provides a stronger connection between autoantibody formation and clotting in COVID-19

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

VA researchers shine light on the dangerous mental health consequences of COVID-19

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

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