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Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Researchers proposed a novel approach to improve intranasal sprays used to treat respiratory viral infections, including SARS-CoV-2 infections.

2 Feb 2022

Rapid dominance of Omicron following its introduction to three Massachusetts universities

Researchers from the United States assessed the rapid dominance of the SARS-CoV-2 Omicron variant in three highly vaccinated Massachusetts university populations.

2 Feb 2022

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Researchers investigated the transmission of the SARS-CoV-2 Delta VOC from infected hamsters to humans.

2 Feb 2022

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A recent study showed that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant is a chimera of two earlier PANGO lineages of SARS-CoV-2.

2 Feb 2022

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

Using best practice guidelines, they developed a mixed-effects deep learning model to classify images as healthy or COVID-19 accurately.

2 Feb 2022

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

New research posted to the medRxiv* preprint server finds patients with immune-mediated inflammatory diseases undergoing anti-TNF therapy had the greatest reduction of antibody levels three months after vaccination. In addition, they had weaker neutralization responses towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

1 Feb 2022

Scientists develop platform to track SARS-CoV-2 lineages

A team of researchers led by Laura D. Hughes from The Scripps Research Institute in California created an online platform called Outbreak.info to track over 40 million lineages and SARS-CoV-2 mutation across 7,000 locations.

1 Feb 2022

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

A team of scientists from the United States has recently demonstrated that current coronavirus disease 2019 (COVID-19) vaccines induce robust spike-specific T cell responses against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Feb 2022

New lab can reveal how ventilation can reduce indoor transmission of airborne infections

Today's buildings and ventilation systems are not built to protect us against the spread of airborne pathogens, and experiences of the current pandemic show that many people are infected indoors in their homes or at workplaces, according to Alan Kabanshi.

1 Feb 2022

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

A large multinational group of researchers has shown how the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gained exceptional immune evasion properties but also a much lower propensity to enter cells such as those in lung alveoli, resulting in its reduced pathogenicity. Their paper is currently released as an unedited version of the manuscript prior to publication in the journal Nature.

1 Feb 2022

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Researchers analyze neutralizing antibodies against the SARS-CoV-2 VOCs with the sera of vaccinated individuals infected with the Omicron variant.

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

Study finds disparities in COVID-19 vaccine hesitancy and uptake among racial, ethnic minorities

People from racial and ethnic minorities in the United States and the United Kingdom were up to three times as likely to report being unsure or unwilling to get a COVID-19 vaccine during the initial vaccine rollout compared to white participants, found a study published in Nature Communications.

1 Feb 2022

Study: COVID-19 infections tend to be milder in fully vaccinated patients

The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study published in the journal Radiology.

1 Feb 2022

Final push needed to achieve full eradication of Guinea worm disease

The number of human cases of Guinea worm disease halved in 2021 to a record low of 14, putting the goal of global eradication in sight, the US-based Carter Center has announced.

1 Feb 2022

Hepatitis E virus can resist most common hand disinfectants, research shows

In Germany and Europe, HEV has its natural reservoir in pigs. The infection can spread from animals to humans, which is called a zoonosis.

1 Feb 2022

Patients with severe COVID-19 may have lower oxygen requirements than previously believed

A new study, led by researchers at Uppsala University, shows that all individual patients suffering from severe COVID-19 may have lower oxygen requirements than was formerly believed. The study was conducted at a Swedish district hospital during the first wave of the pandemic in 2020.

1 Feb 2022

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exogenous trypsin treatment boosts SARS-CoV-2 infection in Vero E6 cells and promotes viral multiplication in cultured cells.

1 Feb 2022

Disease/Infection News

Assessing an intranasal lentiviral booster against COVID-19 variants

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Rapid dominance of Omicron following its introduction to three Massachusetts universities

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

Scientists develop platform to track SARS-CoV-2 lineages

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

New lab can reveal how ventilation can reduce indoor transmission of airborne infections

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Developing post-vaccination SARS-CoV-2 standard reference sera

Study finds disparities in COVID-19 vaccine hesitancy and uptake among racial, ethnic minorities

Study: COVID-19 infections tend to be milder in fully vaccinated patients

Final push needed to achieve full eradication of Guinea worm disease

Hepatitis E virus can resist most common hand disinfectants, research shows

Patients with severe COVID-19 may have lower oxygen requirements than previously believed

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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