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Researchers report encouraging results from experimental antiviral targeting Marburg virus

The Marburg virus, a relative of the Ebola virus, causes a serious, often-fatal hemorrhagic fever. Transmitted by the African fruit bat and by direct human-to-human contact, Marburg virus disease currently has no approved vaccine or antivirals to prevent or treat it.

7 May 2021

Increased symptomatic levels of COVID-19 may be associated with psychiatric symptoms

A significant level of symptoms of depression, anxiety and post-traumatic stress may follow COVID-19 independent of any previous psychiatric diagnoses, according to new research by Columbia University Mailman School of Public Health with colleagues at Universidade Municipal de São Caetano do Sul in Brazil.

7 May 2021

Highly efficient immune response in asymptomatic SARS-CoV-2 patients

Researchers in Singapore have investigated the role of SARS-CoV-2-specific antibodies and T-cells in asymptomatic individuals suffering from COVID-19. They found that, contrary to some initial hypotheses, asymptomatic individuals mount an adaptive immune response on par with symptomatic individuals, demonstrating that T cell response does not appear to be correlated with symptom severity.

7 May 2021

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

In the brain of a person with Alzheimer's disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally.

7 May 2021

New mathematical model predicts disease spread patterns

Early on in the COVID-19 pandemic, health officials seized on contact tracing as the most effective way to anticipate the virus's migration from the initial, densely populated hot spots and try to curb its spread.

7 May 2021

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Patients with cancer have a more challenging time with infections while undergoing treatment — placing them as high-risk for severe COVID-19 illness and death. However, how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with cancer therapies remains poorly understood.

7 May 2021

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

The global spread of COVID-19 has raised serious concern for patients with chronic disease. A correlation has been identified between the severity of COVID-19 and a patient's preexisting comorbidities.

7 May 2021

Bubonic plague had long-term impact on human immune genes, indicates study

Scientists examining the remains of 36 bubonic plague victims from a 16th century mass grave in Germany have found the first evidence that evolutionary adaptive processes, driven by the disease, may have conferred immunity on later generations of people from the region.

7 May 2021

A new method for producing faster and more efficient vaccines

Vaccines are currently a great source of hope for many people, as it is believed they will help to protect society against COVID-19 and pave the way back to a normal life. The current focus is clearly on coronavirus — but vaccines are also fundamental to combating other pathogens.

7 May 2021

Cryptic pocket on the surface of SARS-CoV-2 may be a promising treatment target

In a new study currently available on the bioRxiv* preprint server, a multinational group of researchers modeled an entire membrane-embedded spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and highlighted the potential of a specific mapping approach for unveiling cryptic, potentially druggable pockets on the viral surface.

7 May 2021

Study reports vitamin C inhibits SARS-CoV-2 virus main protease

Based on structural analysis, researchers found that vitamin C binds to 3CLpro, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease essential in viral replication. In vitro cell inhibition studies also showed vitamin C could inhibit 3CLpro, indicating a possible new antiviral treatment method.

6 May 2021

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Researchers have conducted an analysis of nationwide surveillance data from Israel demonstrating the real-world effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 May 2021

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

A study conducted by researchers in Germany has found that the B.1.617 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in India entered certain types of lung and intestine cells with slightly increased efficiency compared with the original wild-type strain.

6 May 2021

Large-scale study focuses on COVID-19 antibodies in asymptomatic and symptomatic patients

MUSC Hollings Cancer Center researchers added to the understanding of the protective immune response against the SARS-CoV-2 virus in a study published in April in iScience.

6 May 2021

COVID-19 vaccination dramatically reduces symptomatic and asymptomatic infections

Vaccination dramatically reduced COVID-19 symptomatic and asymptomatic infections in St. Jude Children's Research Hospital employees compared with their unvaccinated peers, according to a research letter that appears today in the Journal of the American Medical Association.

6 May 2021

India's successful program to eliminate polio provides guidance for mass immunization initiatives

As India urgently scales up its vaccination campaign for the COVID-19 virus, a new study which examined the country's successful program to eliminate polio provides guidance on how this and future mass immunization campaigns can be successful, especially in vaccinating hard to reach groups.

6 May 2021

Survey finds only 41% of people were interested in participating in the COVID-19 vaccine trials

Research conducted by the University of Birmingham shows in order to have an effective COVID-19 vaccination rollout it has to be widely accepted by the entire population.

6 May 2021

Study investigates 12-month respiratory outcomes in patients hospitalized for COVID-19

A new study has shown that most patients discharged from hospital after experiencing severe COVID-19 infection appear to return to full health, although up to a third do still have evidence of effects upon the lungs one year on.

6 May 2021

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

The published data provide additional detail of an initial analysis conducted in January, while more robust data from a complete analysis of the study was subsequently shared in March 2021.

6 May 2021

Unemployed Australian citizens experience mental health deterioration during COVID-19 pandemic, finds study

A team of scientists in Australia has recently investigated the health condition of Australian citizens who lost jobs during the coronavirus disease 2019 (COVID-19) pandemic. The study findings reveal that job loss is associated with a deterioration in mental health but an improvement in physical health. Importantly, retaining employment has shown a positive impact on the overall mental health condition.

6 May 2021

Disease/Infection News

Researchers report encouraging results from experimental antiviral targeting Marburg virus

Increased symptomatic levels of COVID-19 may be associated with psychiatric symptoms

Highly efficient immune response in asymptomatic SARS-CoV-2 patients

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

New mathematical model predicts disease spread patterns

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

Bubonic plague had long-term impact on human immune genes, indicates study

A new method for producing faster and more efficient vaccines

Cryptic pocket on the surface of SARS-CoV-2 may be a promising treatment target

Study reports vitamin C inhibits SARS-CoV-2 virus main protease

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

Large-scale study focuses on COVID-19 antibodies in asymptomatic and symptomatic patients

COVID-19 vaccination dramatically reduces symptomatic and asymptomatic infections

India's successful program to eliminate polio provides guidance for mass immunization initiatives

Survey finds only 41% of people were interested in participating in the COVID-19 vaccine trials

Study investigates 12-month respiratory outcomes in patients hospitalized for COVID-19

Study: Novavax Covid-19 vaccine is efficacious against the B.1.351 South African variant

Unemployed Australian citizens experience mental health deterioration during COVID-19 pandemic, finds study

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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