Disease/Infection News

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SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

U.S. counties need to implement crisis workforce strategies to deal with shortfalls in ICU doctors

Over the next month, 209 U.S. counties in the United States will need to implement crisis workforce strategies to deal with potentially dangerous shortfalls of intensive care unit doctors, according to a new analysis published today.

5 Mar 2021

Research reveals major drivers of increased nicotine and tobacco use during COVID-19 lockdown

Pandemic-related anxiety, boredom, and irregular routines were cited as major drivers of increased nicotine and tobacco use during the initial COVID-19 "lockdown," according to research just released by Columbia University's Mailman School of Public Health.

5 Mar 2021

Study highlights urgent need to monitor legal wildlife trade to reduce emerging zoonotic diseases

With three out of four newly emerging infectious human diseases originating in animals, there is an urgent need to monitor the legal trade in wildlife, according to new research by Vincent Nijman, Professor in Anthropology at Oxford Brookes University.

5 Mar 2021

COVID-19 lockdown has significantly increased loneliness, social issues among women

Social distancing guidelines have reduced the spread of COVID-19, but lockdowns and isolation also have created or aggravated other well-being concerns, reports new research.

4 Mar 2021

Failing to communicate COVID-19 vaccine uncertainties has negative consequences

All healthcare decisions come with uncertainty. In addition to the general risks that a healthcare professional is aware of, there is also uncertainty surrounding the associated probabilities, called ambiguity or radical uncertainties. These uncertainties grow as vaccines generated at an unprecedented pace are administered across the world.

4 Mar 2021

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

A new study reports positive outcomes from two new vaccine candidates. The research, led by Axel T. Lehrer from the University of Hawaii at Manoa, studied mice's immune response when administered the CoVaccine HT adjuvant with an insect-cell expressed SARS-CoV-2 spike protein ectodomain.

4 Mar 2021

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

New research led by Thushan I. de Silva from the University of Sheffield proposes that increases in subgenomic RNA (sgRNA) expression cause increased viral transmissibility and subsequent infection. They suggest the ORF9 protein, found in high amounts of sgRNA, could be regulating interferon responses.

4 Mar 2021

COVID-19 swab testing may not be good for people with a history of sinus or skull-base surgery

People who have had major sinus surgery should consult their ENT doctor before undergoing COVID-19 swab testing, new research indicates.

4 Mar 2021

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing coronavirus disease (COVID-19) caused by the B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently emerged in South Africa.

4 Mar 2021

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

With a relatively minor genetic change, a new treatment developed by researchers at the Georgia Institute of Technology and Emory University appears to stop replication of both flu viruses and the virus that causes Covid-19.

4 Mar 2021

Brazilian SARS-CoV-2 P.1 variant shows resistance to antibody neutralization

Researchers in the United States say the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant – P.1 – that has recently emerged in Brazil shows a worrying level of resistance to neutralization by antibodies.

4 Mar 2021

Inflammatory heart disease is rare among professional athletes with mild COVID-19, study finds

Inflammatory heart disease is a rare finding among professional athletes with mild or asymptomatic COVID-19 infection, a large-scale study has found.

4 Mar 2021

Combining terpenes and cannabidiol may be highly active against human coronaviruses

A group of researchers from a well-known technology company in Israel showed a significant antiviral effect of a combination of terpenes and cannabidiol against a human coronavirus strain 229E. This exciting and first-of-its-kind report is currently available on the bioRxiv preprint server.

4 Mar 2021

Psychiatric and cognitive problems in large number of COVID-19 survivors

A research review led by Oxford Brookes University has found a large proportion of COVID-19 survivors will be affected by neuropsychiatric and cognitive complications.

4 Mar 2021

Administering zinc supplements to Covid-19 patients may help reduce mortality and recovery time

Administering zinc supplements to Covid-19 patients with low levels of this element may be a strategy to reduce mortality and recovery time.

4 Mar 2021

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Researchers found a small molecule that inhibits different virus proteins and significantly reduces infection in cells. Combined with the antiviral remdesivir, its potency increases significantly, suggesting it may be a potential antiviral candidate for the treatment of COVID-19.

4 Mar 2021

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

A prospective observational study has revealed that the late appearance of anti-SARS-CoV-2 antibodies in oral fluid, absence of fever as an early symptom, and elevated BMI are associated with delayed clearance of viral RNA in mild to moderate COVID-19 patients.

4 Mar 2021

Researchers show potential benefits of delaying second mRNA COVID-19 vaccine dose

The currently approved mRNA vaccines from Moderna and Pfizer-BioNTech help create neutralizing antibodies against the SARS-CoV-2 spike protein. Both companies designed their vaccines to be delivered in two doses. However, given the limited supply of vaccines worldwide, a new modeling study has suggested that vaccinating more people with the first dose and delaying the second could be an alternate route to achieving population immunity that could reduce mortality rates.

4 Mar 2021

Disease/Infection News

SARS-CoV-2 proteins are potent suppressors of innate immunity

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

U.S. counties need to implement crisis workforce strategies to deal with shortfalls in ICU doctors

Research reveals major drivers of increased nicotine and tobacco use during COVID-19 lockdown

Study highlights urgent need to monitor legal wildlife trade to reduce emerging zoonotic diseases

COVID-19 lockdown has significantly increased loneliness, social issues among women

Failing to communicate COVID-19 vaccine uncertainties has negative consequences

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

COVID-19 swab testing may not be good for people with a history of sinus or skull-base surgery

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

Brazilian SARS-CoV-2 P.1 variant shows resistance to antibody neutralization

Inflammatory heart disease is rare among professional athletes with mild COVID-19, study finds

Combining terpenes and cannabidiol may be highly active against human coronaviruses

Psychiatric and cognitive problems in large number of COVID-19 survivors

Administering zinc supplements to Covid-19 patients may help reduce mortality and recovery time

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

Researchers show potential benefits of delaying second mRNA COVID-19 vaccine dose

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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