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New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

One-third of COVID-19 survivors manifest neurological problems

In a longitudinal study recently published on the preprint server medRxiv*, Andrea Pilotto et al. find that one-third of COVID-19 infection survivors have long-term neurological manifestations after hospitalization.

5 Jan 2021

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

Researchers investigating attitudes towards vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among the UK population have found that, overall, most people were willing to accept a vaccine.

5 Jan 2021

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

Three teams at Binghamton University awarded grants to pursue COVID-19 research projects

The State University of New York has awarded grants of up to $10,000 to three teams at Binghamton University to pursue research projects related to COVID-19.

5 Jan 2021

COVID-19 vaccination in UK may not lead to relaxation of control measures

Researchers have warned that early relaxation of coronavirus disease 2019 (COVID-19) control measures in the UK could lead to pronounced waves of further infection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Jan 2021

Cellid, IVI sign research service contract to evaluate immunogenicity of COVID-19 vaccine

Cellid and the International Vaccine Institute have exchanged a collaborative research agreement to analyze the immunogenicity of the COVID-19 vaccine "AdCLD-CoV19".

5 Jan 2021

Increased COVID-19 infections following the reopening of Florida schools

Reopening Florida elementary and high schools in September was followed by increased COVID-19 infections, according to data analyzed by Ben-Gurion University of the Negev, Harvard Medical School and Tel Aviv University researchers.

5 Jan 2021

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Using monoclonal antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and senescent markers, researchers provide evidence that virus-infected lung cells acquire characteristics of cellular senescence, which also leads to expression of proinflammatory cytokines.

5 Jan 2021

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

Researchers conducted a mass, asymptomatic screening of patients in dental surgeries across Scotland to assess illustrate its potential utility in curbing silent transmission.

5 Jan 2021

Copper surfaces can inactivate SARS-CoV-2 in as little as one minute, study finds

A new study by researchers at the University of Southampton, UK, has found that SARS-CoV-2 can inactivate on copper surfaces in as little as 1 minute. This is faster than the findings of previous studies in which it took as much as 4 hours before the virus was inactivated.

5 Jan 2021

Can interregional travel restrictions curb SARS-CoV-2 transmission?

A study led by Dr. Keisuke Kondo at the Research Institute of Economy, Trade and Industry, Japan, has recently developed a mathematical model to investigate the impacts of interregional mobility restriction on the transmission of SARS-CoV-2.

5 Jan 2021

Looking to the future will help safeguard mental wellbeing during future Covid-19 lockdowns

Practicing gratitude and looking to the future will help safeguard our mental wellbeing during future Covid-19 lockdowns, a new study in the Journal of Positive Psychology reports.

5 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers from Mexico demonstrate how they calculated age-stratified COVID-19 case fatality rates, years of life lost (YLL), and relative risk for 9 comorbidities and 23 comorbidity combinations in a retrospective study.

5 Jan 2021

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

By conducting a state-of-the-art interactome study between SARS-CoV-2 and host cells, researchers from the University of Texas MD Anderson Cancer Center in Houston identified 437 human proteins as the high-confidence interacting proteins – with substantial implications for understanding coronavirus disease 2019 (COVID-19) pathology and potential treatments.

5 Jan 2021

Disease/Infection News

New mathematical model proposes optimal treatment strategies for COVID-19

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

One-third of COVID-19 survivors manifest neurological problems

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Three teams at Binghamton University awarded grants to pursue COVID-19 research projects

COVID-19 vaccination in UK may not lead to relaxation of control measures

Cellid, IVI sign research service contract to evaluate immunogenicity of COVID-19 vaccine

Increased COVID-19 infections following the reopening of Florida schools

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

Copper surfaces can inactivate SARS-CoV-2 in as little as one minute, study finds

Can interregional travel restrictions curb SARS-CoV-2 transmission?

Looking to the future will help safeguard mental wellbeing during future Covid-19 lockdowns

A paper-based sensor for detecting COVID-19

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

Researchers develop immunity monitoring to determine the efficacy of COVID-19 vaccine

Sugar-binding protein could promote inflammation and worsen sepsis

Heading off the next pandemic

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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