Disease/Infection News

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Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

In a recent medRxiv research paper, the US scientists examined the effects of non-synonymous mutations in the circulating B.1.1.7 strain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on linear antibody epitope signal for viral spike glycoprotein and nucleoprotein – and demonstrated that mutations should not result in immune evasion.

11 Jan 2021

Infectious disease early warning system compensates for existing gaps in surveillance

Researchers at Columbia University Mailman School of Public Health developed an infectious disease early warning system that includes areas lacking health clinics participating in infectious disease surveillance.

11 Jan 2021

Study finds association between severity of COVID-19 and shorter telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.

11 Jan 2021

Over half of COVID-19 cases are spread by asymptomatic carriers, CDC study finds

In a new study conducted by researchers at the U.S. Centers for Disease Control and Prevention (CDC), over half of SARS-CoV-2 infections are believed to be transmitted asymptomatically.

11 Jan 2021

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

A recent study has found that extracellular vimentin can bind to SARS-CoV-2 spike protein in vitro, and antibodies against vimentin can decrease virus infectivity by up to 80%. This suggests vimentin could aid the virus’s binding to host cells and help in infection.

11 Jan 2021

Could Ivermectin be an effective antiviral against SARS-CoV-2?

A double-blind, randomized, placebo-controlled clinical trial has recently demonstrated that Ivermectin, an anti-parasitic drug, can reduce in-hospital mortality rate of COVID-19 patients.

11 Jan 2021

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Scientists from Germany and China recently conducted a large meta-analysis using transcriptome data of SARS-CoV-2 to evaluate the routes of viral entry and the characteristics of innate immune responses induced by SARS-CoV-2 infection.

11 Jan 2021

How effective are masks in preventing SARS-CoV-2 transmission?

Can face masks protect against SARS-CoV-2 infection? Faruque Ahmad, MD, recently explored the role of face masks in mitigating the coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2.

11 Jan 2021

Seroprevalence and asymptomatic carrier status of SARS-CoV-2 in China

As asymptomatic transmission chains play a role in SARS-CoV-2’s viral spread, a new study by researchers in Wuhan, China, investigated the seroprevalence and asymptomatic carrier status of SARS-CoV-2 in the region.

11 Jan 2021

Researchers reach important milestone in leishmaniasis vaccine development

Researchers have taken an important step forward in developing a controlled human infection model to test leishmaniasis vaccines.

11 Jan 2021

Study suggests link between T. gondii infection and risk of aggressive brain cancer

A new study suggests a link between toxoplasma gondii (T. gondii) infection and the risk of glioma, a type of brain cancer, in adults.

11 Jan 2021

New agent-based model can be used for making informed choices regarding COVID-19 restrictions

What happens when municipalities in the Copenhagen area experience a COVID-19 flare-up? Would closing the schools have any effect, or would a better choice be directing the parents to work from home? Due to the COVID-19 pandemic, authorities worldwide have several times implemented steps to keep the pandemic in check.

11 Jan 2021

Is your covid vaccine venue prepared to handle rare, life-threatening reactions?

As the rollout of covid-19 vaccines picks up across the U.S., moving from hospital distribution to pharmacies, pop-up sites and drive-thru clinics, health experts say it's vital that these expanded venues be prepared to handle rare but potentially life-threatening allergic reactions.

11 Jan 2021

Researchers receive NIH grant to develop more effective flu vaccines

To build better vaccines, scientists want to know more about how our bodies make adequate numbers of effective, durable antibodies against the influenza virus.

11 Jan 2021

Anti-Black racism in Canada’s health care impacts people’ health, argue experts

Canada must dismantle anti-Black racism in health care to address its harmful effects on people's health, argue authors of a commentary in CMAJ (Canadian Medical Association Journal)

11 Jan 2021

Study: Oral sex can increase risk of HPV-related oropharyngeal cancer

Human papillomavirus (HPV) can infect the mouth and throat to cause cancers of the oropharynx. A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, has found that having more than 10 prior oral sex partners was associated with a 4.3-times greater likelihood of having HPV-related oropharyngeal cancer.

11 Jan 2021

Schlieren techniques demonstrate patterns of exhaled air spread from wind instruments and singers

In an interesting new research paper published recently on the bioRxiv preprint server, scientists describe the dispersal of exhaled air, potentially infected, from singers and those playing wind instruments, using Schlieren techniques, a visual process that is used to photograph the flow of fluids of varying density. This could help assess measures to assess the actual spread of infectious droplets or aerosols in such situations.

10 Jan 2021

Tetherin downregulation by SARS-CoV-2 enhances viral spread

A new preprint research paper published on the bioRxiv server describes the role of a host protein called tetherin in the spread of the novel coronavirus.

10 Jan 2021

Synthetic lung organoids provide high-throughput platform to identify new cellular targets of SARS-CoV-2

An interesting new study published on the bioRxiv preprint server describes a new platform that allows a high-throughput workflow to generate matched human lung buds in the tens of thousands. This allows researchers to study SARS-CoV-2 infection and therapeutics in lung tissue that mirrors the key aspects of human lung development.

10 Jan 2021

Large-scale genome sequencing shows how SARS-CoV-2 mutated

A new study published on the preprint server bioRxiv* describes the results of genomic sequencing of the virus, which may help trace the routes of transmission of the virus from person to person, and from country to country.

10 Jan 2021

Disease/Infection News

Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

Infectious disease early warning system compensates for existing gaps in surveillance

Study finds association between severity of COVID-19 and shorter telomeres

Over half of COVID-19 cases are spread by asymptomatic carriers, CDC study finds

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

Could Ivermectin be an effective antiviral against SARS-CoV-2?

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

How effective are masks in preventing SARS-CoV-2 transmission?

Seroprevalence and asymptomatic carrier status of SARS-CoV-2 in China

Researchers reach important milestone in leishmaniasis vaccine development

Study suggests link between T. gondii infection and risk of aggressive brain cancer

New agent-based model can be used for making informed choices regarding COVID-19 restrictions

Is your covid vaccine venue prepared to handle rare, life-threatening reactions?

Researchers receive NIH grant to develop more effective flu vaccines

Anti-Black racism in Canada’s health care impacts people’ health, argue experts

Study: Oral sex can increase risk of HPV-related oropharyngeal cancer

Schlieren techniques demonstrate patterns of exhaled air spread from wind instruments and singers

Tetherin downregulation by SARS-CoV-2 enhances viral spread

Synthetic lung organoids provide high-throughput platform to identify new cellular targets of SARS-CoV-2

Large-scale genome sequencing shows how SARS-CoV-2 mutated

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