Drug Discovery & Pharmaceuticals

RSS

Bacterial toxin stimulates tissue regeneration

Normally they are among the many harmless organisms found in and on the human body: one in four people have millions of Staphylococcus aureus bacteria on their skin and on the mucous membranes of the upper respiratory tract, without being aware of it.

13 Oct 2020

Study examines the pharmacogenomics of opioid addiction

In one of the first studies of its kind, a University of Cincinnati researcher is using a grant from the Ohio attorney general's office to research the pharmacogenomics of opioid addiction.

13 Oct 2020

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

12 Oct 2020

Chemists suggest a new domino reaction to produce organic compounds against cancers

A team of chemists from RUDN University suggested a new reaction to produce organic compounds in one vessel.

9 Oct 2020

New efficacies of Ganoderma lucidum as anti-inflammatory agent for the skin

Ganoderma lucidum, known as Yeongji mushroom in Korea, is called a modern-day elixir plant and has long been used medicinally in China, Japan and Korea.

7 Oct 2020

New deep learning-based technique could boost drug development

When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.

5 Oct 2020

Supporting Coronavirus Research with Liquid Chromatography

The RNA in viruses such as SARS-CoV-2 are an ideal research target. RNA purification with liquid chromatography is essential in the fight against SARS-CoV-2.

From KNAUER Wissenschaftliche Geräte GmbH 5 Oct 2020

Study offers explanation for why people's responses to the same drug vary widely

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

1 Oct 2020

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

The U.S. Food and Drug Administration has granted Fast Track designation to a novel "switchable" CAR-T cell therapy developed by Calibr, a division of Scripps Research, in a move to accelerate the drug development and review process.

1 Oct 2020

Compounds repurposed from malaria treatment can kill diarrheal pathogen

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

1 Oct 2020

Planaria flatworm can be used as reliable alternative for testing topical skin products

Tests for skin treatments could be screened using flatworms rather than other animals such as rabbits, according to new research.

1 Oct 2020

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from replicating.

30 Sep 2020

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body.

29 Sep 2020

Researchers develop a new substance that can disarm tumor-promoting proteins

The villain in this drama has a pretty name: Aurora - Latin for dawn. In the world of biochemistry, however, Aurora (more precisely: Aurora-A kinase) stands for a protein that causes extensive damage. There, it has been known for a long time that Aurora often causes cancer.

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

AXT is excited to add the Vieworks range of bio-imaging systems to their preclinical imaging product portfolio. Their in-vivo imaging systems provide outstanding performance in bioluminescent and fluorescent imaging and represents excellent value.

From AXT Pty Ltd 26 Sep 2020

Quantum simulators could help create tomorrow's pharmaceuticals

Trial and error define today's approach to developing new pharmaceutical drugs. But with their enormous computing power, quantum computers are expected to solve important and complex problems in medicine, biology and chemistry, while speeding up the discovery of effective medications.

23 Sep 2020

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

23 Sep 2020

Researchers identify a potential drug candidate for hand, foot and mouth disease

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children

22 Sep 2020

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

A team of scientists from the National Center for Advancing Translational Sciences and Naval Research Laboratory in Washington, D.C., has developed a new tool that mimics how SARS-CoV-2 -- the virus that causes COVID-19 -- infects a cell, information that could potentially speed the search for treatments against the disease.

22 Sep 2020

Drug Discovery & Pharmaceuticals

Bacterial toxin stimulates tissue regeneration

Study examines the pharmacogenomics of opioid addiction

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

Chemists suggest a new domino reaction to produce organic compounds against cancers

New efficacies of Ganoderma lucidum as anti-inflammatory agent for the skin

New deep learning-based technique could boost drug development

Supporting Coronavirus Research with Liquid Chromatography

Study offers explanation for why people's responses to the same drug vary widely

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

Compounds repurposed from malaria treatment can kill diarrheal pathogen

Planaria flatworm can be used as reliable alternative for testing topical skin products

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Researchers develop a new substance that can disarm tumor-promoting proteins

Valproic acid can interact with DNA conformation and regulate gene expression

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

Quantum simulators could help create tomorrow's pharmaceuticals

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

Researchers identify a potential drug candidate for hand, foot and mouth disease

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Latest Life Science News