Drug Discovery & Pharmaceuticals

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Researchers develop a new substance that can disarm tumor-promoting proteins

The villain in this drama has a pretty name: Aurora - Latin for dawn. In the world of biochemistry, however, Aurora (more precisely: Aurora-A kinase) stands for a protein that causes extensive damage. There, it has been known for a long time that Aurora often causes cancer.

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

AXT is excited to add the Vieworks range of bio-imaging systems to their preclinical imaging product portfolio. Their in-vivo imaging systems provide outstanding performance in bioluminescent and fluorescent imaging and represents excellent value.

From AXT Pty Ltd 26 Sep 2020

Quantum simulators could help create tomorrow's pharmaceuticals

Trial and error define today's approach to developing new pharmaceutical drugs. But with their enormous computing power, quantum computers are expected to solve important and complex problems in medicine, biology and chemistry, while speeding up the discovery of effective medications.

23 Sep 2020

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

23 Sep 2020

Researchers identify a potential drug candidate for hand, foot and mouth disease

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children

22 Sep 2020

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

A team of scientists from the National Center for Advancing Translational Sciences and Naval Research Laboratory in Washington, D.C., has developed a new tool that mimics how SARS-CoV-2 -- the virus that causes COVID-19 -- infects a cell, information that could potentially speed the search for treatments against the disease.

22 Sep 2020

Ziath introduces new products to assist compound management labs using Acoustix tubes

Ziath has released a module to enable their Mirage, Cube or Express tube readers to decode Brooks Acoustix tubes.

From Ziath Ltd 18 Sep 2020

RUDN geneticist finds a bifidobacterial protein that can reduce inflammation in COVID-19

A geneticist from RUDN University studied the effect of Bifidobacterium (intestinal bacteria) on the inflammatory process and discovered that their surface protein is capable of stopping excessive or uncontrollable inflammation, like the one observed in COVID-19 patients.

14 Sep 2020

Tiny antibody component shows high potency in SARS-CoV-2 animal models

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19.

14 Sep 2020

New bone-on-a-chip device could revolutionize pharmaceutical pre-clinical testing

A new technology that could be used to test new treatments for human organs and bone tissue - all whilst reducing the need for animal research - has been developed by engineers at the University of Sheffield.

14 Sep 2020

Cell signaling research rings warning bells over an emerging cancer drug target

Researchers at the Babraham Institute have used their understanding of cellular signalling to highlight a pitfall in an emerging treatment for cancer and inflammation.

14 Sep 2020

CN Bio partners with Imperial College London to uncover therapeutic targets for alcoholic hepatitis

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced a collaboration with Imperial College London, a world-class research university.

10 Sep 2020

Optibrium’s peer-reviewed study highlights the value of deep learning to impute drug discovery data

Optibrium, leading providers of software and services for drug discovery, today announced a peer-reviewed publication, ‘Practical Applications of Deep Learning to Impute Heterogeneous Drug Discovery Data’, in the Journal of Chemical Information and Modeling.

10 Sep 2020

Exploring the Relationship Between Mass Spectrometry and Informatics

Mass spectrometry has always had a powerful synergy with computers. Computers have pushed mass spectrometry forward at key junctures in it’s history from data collection to instrument operation to data analysis.

From Bruker Life Sciences Mass Spectrometry 9 Sep 2020

New bio-active natural products with huge potential as drugs

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives.

8 Sep 2020

Moving towards a new age of personalized, cell-based interceptive medicine for Europe

Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

7 Sep 2020

Study shows how genetic data can be used to prioritize drug targets for complex diseases

An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit at the University of Bristol, has demonstrated how genetic data can be used to support drug target prioritisation by identifying the causal effects of proteins on diseases.

7 Sep 2020

Relation Therapeutics announces Project RE to identify COVID-19 therapeutic candidates

Relation Therapeutics, a drug development company driven by data science and machine learning, today announces Project RE, which will apply Relation Therapeutics’ and its partners’ technology to the identification of repurposed drug combinations as potential therapeutic candidates for COVID-19.

3 Sep 2020

Scientists aim to find cortisone alternatives with fewer side effects

Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19.

2 Sep 2020

Drug Discovery & Pharmaceuticals

Researchers develop a new substance that can disarm tumor-promoting proteins

Valproic acid can interact with DNA conformation and regulate gene expression

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

Quantum simulators could help create tomorrow's pharmaceuticals

New T-cell-based vaccine strategy provides broader protection against seasonal influenza

Researchers identify a potential drug candidate for hand, foot and mouth disease

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

Ziath introduces new products to assist compound management labs using Acoustix tubes

RUDN geneticist finds a bifidobacterial protein that can reduce inflammation in COVID-19

Tiny antibody component shows high potency in SARS-CoV-2 animal models

New bone-on-a-chip device could revolutionize pharmaceutical pre-clinical testing

Cell signaling research rings warning bells over an emerging cancer drug target

CN Bio partners with Imperial College London to uncover therapeutic targets for alcoholic hepatitis

Optibrium’s peer-reviewed study highlights the value of deep learning to impute drug discovery data

Exploring the Relationship Between Mass Spectrometry and Informatics

New bio-active natural products with huge potential as drugs

Moving towards a new age of personalized, cell-based interceptive medicine for Europe

Study shows how genetic data can be used to prioritize drug targets for complex diseases

Relation Therapeutics announces Project RE to identify COVID-19 therapeutic candidates

Scientists aim to find cortisone alternatives with fewer side effects

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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