Drug Discovery & Pharmaceuticals

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Researchers develop new drug discovery method targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

28 Dec 2020

New drug combination improves blood glucose control and weight loss in mice

Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife.

22 Dec 2020

Autobahn Labs announces a strategic drug discovery partnership with UCSF

Autobahn Labs, a virtual incubator partnering with top academic and research institutions to catalyze early-stage drug discovery and development, today announced a strategic collaboration with the University of California San Francisco (UCSF).

21 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Anti-hypertension drug may be key to extending lifespan, shows study

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

18 Dec 2020

Supercomputer simulations lead to an important viral inhibitor discovery

University of New Hampshire researchers recently used Comet at the San Diego Supercomputer Center at UC San Diego and Stampede2 at the Texas Advanced Computing Center to identify new inhibitor binding/unbinding pathways in an RNA-based virus.

17 Dec 2020

New tool aids in the discovery of RNA medicines for undruggable diseases

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some "undruggable" diseases, including a type of metastatic breast cancer.

15 Dec 2020

Researchers develop new technology for efficient production of monoclonal antibodies

Proteins in biopharmaceutical productions are usually separated and purificated through the expensive chromatography technique. European researchers are developing an innovative membrane crystallization technology to overcome the issue and make the production of monoclonal antibodies more efficient.

15 Dec 2020

Reliable Antibodies Testing for SARS-CoV-2

In this interview, Poncho Meisenheimer, VP of R&D at Promega, talks to News-Medical Life Sciences about the importance of having the reliability for SARS-Co-V-2 antibody tests.

From Promega Corporation 15 Dec 2020

RUDN chemists discover previously unknown derivatives of chitin

Chemists from RUDN University discovered previously unknown derivatives of chitin, a biopolymer that forms the exoskeletons of insects and carapaces of crayfish and other arthropods.

14 Dec 2020

£453,000 grant awarded to boost research and development for COVID-19 antibodies

Fusion Antibodies, pre-clinical antibody discovery, engineering and supply experts, and Queen’s University Belfast, leader in innovation and impact, have been awarded a £453,000 grant from Invest Northern Ireland to further expand their COVID-19 targeted research and development efforts.

14 Dec 2020

Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

Possible new antibiotic developed for drug-resistant pulmonary pathogen

Scientists from Johns Hopkins University and Medicine have developed a possible new antibiotic for a pathogen that is notoriously resistant to medications and frequently lethal for people with cystic fibrosis and other lung ailments.

8 Dec 2020

Advances in Microplate Technology at SLAS 2021

Porvair Sciences will exhibit its latest specialist microplates and microplate instrumentation at the forthcoming SLAS 2021 Digital International Conference and Exhibition (January 25-27th 2021).

From Porvair Sciences Limited 3 Dec 2020

Tackling the Global Issue of New Psychoactive Substances

News-Medical speaks to Dr. Venita Decker, Dr. Joerg Koehler, and Dr. Andrea Kiehne about the latest challenges in narcotic analysis, and the methods being implemented to help tackle this global NPS issue.

From Bruker BioSpin - NMR, EPR and Imaging 2 Dec 2020

A Low Temperature Flow Reactor Module

The Cold Coil II™ Flow Reactor Module from Uniqsis is designed to provide a flexible, entry-level solution for low temperature flow chemistry applications.

From Uniqsis Ltd 2 Dec 2020

Lemann Foundation hails "spirit of co-operation' during wide-scale Brazilian clinical trial of Oxford/AstraZeneca vaccine

Denis Mizne, CEO of the Lemann Foundation, today hailed the “spirit of co-operation” during the wide-scale Brazilian clinical trials that helped deliver the Oxford/AstraZeneca COVID-19 vaccine, following the news that it is up to 90% per cent effective after passing phase-3 global trials.

27 Nov 2020

Inexpensive molecule shows potential to fight antibiotic-resistant bacteria causing gonorrhea, meningitis

A team from the Institut national de la recherche scientifique (INRS) has demonstrated the effectiveness of an inexpensive molecule to fight antibiotic-resistant strains of the bacteria responsible for gonorrhea and meningococcal meningitis.

24 Nov 2020

FairJourney Biologics and IONTAS sign agreement with Pandion Therapeutics to discover antibodies

FairJourney Biologics S.A (FJB) and IONTAS Limited, leaders in the discovery and optimization of VHH and fully human antibodies, today announced they have signed an agreement to discover antibodies with Pandion Therapeutics.