Drug Discovery & Pharmaceuticals

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Researchers characterize a potential therapeutic target to weaken COVID-19

When invaded by a virus, our body cells launch an alert to neighboring cells to increase their antiviral defenses to prevent the infection from spreading.

24 Mar 2021

New compound may provide a basis for drug development against COVID-19

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, arrived one year ago and turned our lives upside-down.

24 Mar 2021

Three commonly used antiviral drugs potentially effective at preventing replication of SARS-CoV-2

An international team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at preventing replication of SARS-CoV-2, the virus that causes COVID-19.

24 Mar 2021

New method could drive down the production cost of antibodies

Antibody injections are a highly desirable treatment for people with chronic diseases such as cancer, psoriasis, Crohn's disease and arthritis. And recently, antibodies have been in the news as a promising treatment for severe cases of COVID-19.

22 Mar 2021

New antibiotic compound can effectively clear multi-drug resistant gonorrhea in animals

A new antibiotic compound clears infection of multi-drug resistant gonorrhea in mice in a single oral dose, according to a new study led by researchers at Penn State and Emory University.

19 Mar 2021

New high-throughput system for testing drug candidates to treat brain diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

18 Mar 2021

Using iodine as catalyst to advance the sustainability of pharmaceutical syntheses

Synthesizing pharmaceuticals for cancer, viral diseases, and other medical conditions is slow work. A particularly challenging chemical transformation is to start with what's known as an unactivated alkene--a common molecular building block--and end up with a vicinal diamine; i.e., installation of two nitrogen units into carbon--carbon double bonds.

16 Mar 2021

New machine learning technique could quicken the pace of drug discovery

Drugs can only work if they stick to their target proteins in the body. Assessing that stickiness is a key hurdle in the drug discovery and screening process. New research combining chemistry and machine learning could lower that hurdle.

15 Mar 2021

48Hour Discovery and Merck join hands to accelerate drug development

48Hour Discovery and CQDM are proud to announced that the company has been awarded $800,000 for peptide drug discovery using its patented drug discovery platform.

15 Mar 2021

Understanding how a polymer inhibits ice re-crystallization could guide design of new cryoprotectants

When biological material (cells, blood, tissues) is frozen, cryoprotectants are used to prevent the damage associated with the formation of ice during the freezing process.

15 Mar 2021

NTU scientists design new compound that could help reduce overactive immune response

When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.

10 Mar 2021

Discover, Visualize and Identify Biomarkers

In this interview, Lucy Woods from Bruker Daltonics talks to News-Medical Life Sciences about the new MetaboScape to help identify and discover more biomarkers.

From Bruker Life Sciences Mass Spectrometry 10 Mar 2021

Project Helios launched to unlock new approaches in small molecule drug discovery

The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Orionis Biosciences today announced the launch of Project Helios, a research collaboration designed to unlock new drug development opportunities through genome-scale mapping of drug-target interactions.

9 Mar 2021

Weedy grass may be effective against several human diseases

Native to the southeastern United States, a weedy grass has spread northward to Canada and also made its way to Australia and Japan. Andropogon virginicus grows densely packed and up to seven feet tall, disrupting growth patterns of other plants and competing for resources.

8 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Scientists from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy.

5 Mar 2021

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pancreatitis drug Camostat inhibits new SARS-CoV-2 activators identified in the upper respiratory tract. There are no therapeutics available that have been developed for COVID-19 treatment.

5 Mar 2021

Pharmacists discover active substances that block SARS-CoV-2 replication

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease.

3 Mar 2021

Analytical Mass Spectrometry: How Did We Get Here, Where are We Going?

News-Medical interviews Rick Yost, winner of the Pittsburgh Analytical Chemistry Award 2021, about his research into mass spectrometry.

From Pittcon 3 Mar 2021

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications.

2 Mar 2021

Drug Discovery & Pharmaceuticals

Researchers characterize a potential therapeutic target to weaken COVID-19

New compound may provide a basis for drug development against COVID-19

Three commonly used antiviral drugs potentially effective at preventing replication of SARS-CoV-2

New method could drive down the production cost of antibodies

New antibiotic compound can effectively clear multi-drug resistant gonorrhea in animals

New high-throughput system for testing drug candidates to treat brain diseases

Using iodine as catalyst to advance the sustainability of pharmaceutical syntheses

New machine learning technique could quicken the pace of drug discovery

48Hour Discovery and Merck join hands to accelerate drug development

Understanding how a polymer inhibits ice re-crystallization could guide design of new cryoprotectants

NTU scientists design new compound that could help reduce overactive immune response

Discover, Visualize and Identify Biomarkers

Project Helios launched to unlock new approaches in small molecule drug discovery

Weedy grass may be effective against several human diseases

New, efficient method facilitates antibody development

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pharmacists discover active substances that block SARS-CoV-2 replication

Analytical Mass Spectrometry: How Did We Get Here, Where are We Going?

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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