Drug Discovery & Pharmaceuticals

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Researchers produce first fully-glycosylated full-length SARS-CoV-2 spike protein models

The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The "spike" or S protein facilitates viral entry into host cells.

22 Jun 2020

TPU researchers develop supersensitive sensors to detect enantiomers in drugs

Researchers of Tomsk Polytechnic University collaboratively with colleagues from the Czech Republic developed supersensitive sensors for detecting enantiomers, known as 'mirror molecules', in drugs.

19 Jun 2020

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Cyclic peptide molecules of the fungal origin called cyclosporins were discovered in 1970's, and cyclosporin A soon became an important drug due to its immunosuppressive activity.

18 Jun 2020

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Scientists from Nanyang Technological University, Singapore have developed a sustainable and green way to extract high-quality antimicrobial compounds from seeds.

17 Jun 2020

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

Cobra Biologics, part of the Cognate BioServices family, an international CDMO for biologics and pharmaceuticals, today announced it has signed a supply agreement with AstraZeneca UK Ltd. to provide GMP manufacture of the adenovirus vector-based COVID-19 vaccine candidate AZD1222, previously known as ChAdOx1 n-CoV-19.

From AstraZeneca 17 Jun 2020

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

An interview with Livia Eberlin, Assistant Professor at the University of Texas at Austin, discussing the development of mass-spectrometry based techniques for cancer diagnosis and improved clinical outcomes.

From Pittcon 16 Jun 2020

Sygnature Discovery supports New York Medical College pharmacologist in the fight against Covid-19

Sygnature Discovery, a leading independent integrated drug discovery and pre-clinical services company, is supporting Professor Sachin Gupte, a pharmacologist at the New York Medical College, in his endeavours to find a drug treatment for the lung damage that can result from Covid-19 infection.

From Sygnature Discovery Limited 15 Jun 2020

Determining Cannabinoids in Marijuana-Infused Edibles

Marijuana-infused edibles or medibles have increased immensely over the last 10 years. With products such as brownies and gummy bears infused with marijuana, it is more important now than ever to test these cannabis-related products.

From Pittcon 12 Jun 2020

Phenothiazine derivatives show high potential for use in photodynamic therapy

A group on organic compounds under Professor Ivan Stoikov's guidance has been working on phenothiazine derivatives at Kazan Federal University since 2016.

9 Jun 2020

Research shows potential new therapeutic strategy for slowing down Huntington's disease

Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington's disease in a new study published today in eLife.

9 Jun 2020

Old antibiotic may be a powerful new tool against deadly superbug

USC researchers have discovered that an old antibiotic may be a powerful new tool against a deadly superbug, thanks to an innovative screening method that better mimics conditions inside the human body.

8 Jun 2020

Research team identifies key ingredients for producing high-value chemical compounds

Researchers have identified key ingredients for producing high-value chemical compounds in an environmentally friendly fashion: repurposed enzymes, curiosity, and a little bit of light.

8 Jun 2020

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

UTEP researchers unlock potential of carbon quantum dots to combat neurological disorders

The contributions of researchers from The University of Texas at El Paso (UTEP) have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders, according to a paper published in the journal Processes as part its special issue on protein biosynthesis and drug design and delivery.

5 Jun 2020

New ECL-based mechanism enables development of increasingly efficient serological tests

A research group led by the University of Bologna identified a new mechanism that allows to obtain serological tests that are quicker, more cost-effective and more reliable than those currently in use.

5 Jun 2020

Using supercomputers to knock out drug side effects

Psychedelic drugs could be effective in treating psychiatric disorders such as depression and post-traumatic stress disorder, but medical use of these drugs is limited by the hallucinations they cause.

4 Jun 2020

Two marine molecules show potential to treat Alzheimer's disease

An interdisciplinary research study of the University of Barcelona identified two potential candidates to treat Alzheimer's disease. These are two marine molecules, meridianine and lignarenone B, able to alter the activity of GSK3B activity, a protein associated with several neurodegenerative diseases.

28 May 2020

Hydrocarbon bonds may help synthesize large range of novel organic molecules

The most common chemical bond in the living world -- that between carbon and hydrogen -- has long resisted attempts by chemists to crack it open, thwarting efforts to add new bells and whistles to old carbon-based molecules.

22 May 2020

New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Researchers from the Muñiz group have published a paper in Angewandte Chemie - International Edition presenting a new metal-free methodology for the photo-catalyzed nucleophilic fluorination of aliphatic hydrocarbon bonds.

21 May 2020

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, and Celonic Group, a premium biopharmaceutical CDMO specialized in the development and production of Advance Therapy Medicinal Products (ATMPs) and mammalian cell line-expressed biotherapeutics, today announced a collaboration to produce the novel human recombinant protein AT-100 (rhSP-D) as a therapeutic candidate against COVID-19.

21 May 2020

Drug Discovery & Pharmaceuticals

Researchers produce first fully-glycosylated full-length SARS-CoV-2 spike protein models

TPU researchers develop supersensitive sensors to detect enantiomers in drugs

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

Accelerating the Diagnosis and Treatment of Cancer with Mass-Spectrometry Based Techniques

Sygnature Discovery supports New York Medical College pharmacologist in the fight against Covid-19

Determining Cannabinoids in Marijuana-Infused Edibles

Phenothiazine derivatives show high potential for use in photodynamic therapy

Research shows potential new therapeutic strategy for slowing down Huntington's disease

Old antibiotic may be a powerful new tool against deadly superbug

Research team identifies key ingredients for producing high-value chemical compounds

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

UTEP researchers unlock potential of carbon quantum dots to combat neurological disorders

New ECL-based mechanism enables development of increasingly efficient serological tests

Using supercomputers to knock out drug side effects

Two marine molecules show potential to treat Alzheimer's disease

Hydrocarbon bonds may help synthesize large range of novel organic molecules

New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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