Drug Discovery & Pharmaceuticals

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Drug-discovery collaboration finds potential new antimalarial drug candidates

Potential new antimalarial drug candidates are being developed through an extended drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation.

22 Apr 2021

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization.

21 Apr 2021

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Human clinical trials have begun on a new vaccine candidate that may protect against not only SARS-CoV-2, the virus that causes COVID-19, but against at least two of the variants emerging around the world.

21 Apr 2021

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Unless you've studied chemistry in college, it's unlikely you've come across the name aziridine. An organic compound with the molecular formula, C2H4NH, aziridines are well-known among medicinal chemists, who make use of the compound to prepare pharmaceutical drugs such as Mitomycin C, a chemotherapeutic agent known for its anti-tumor activity.

20 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for Coronavirus.

16 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

Linkam FDCS196 stage used in research to develop a novel transdermal delivery system for risperidone

The first study of its kind reports on the enhancement of skin permeability of risperidone (RIS) using eutectic systems.

From Linkam Scientific Instruments 14 Apr 2021

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.

13 Apr 2021

Natural treatment based on flour made from mealworms can help prevent Type II diabetes mellitus

Scientists from the Bioreactors Research Group of the University of Granada have demonstrated that a natural treatment based on flour made from the insect Tenebrio molitor (more commonly known as the mealworm) can help prevent Type II diabetes mellitus.

13 Apr 2021

MagnaPharm project opens up new possibilities in drug production

Polymorphs are crystalline materials that have the same chemical composition but different molecular packing. For example, diamond and graphite are both made from crystalline forms of carbon, but their physical and chemical properties vary drastically.

13 Apr 2021

BGU researchers identify probiotic yogurt-based drug candidates

Researchers at Ben-Gurion University of the Negev (BGU) have for the first time identified new drug candidates based on molecules isolated from probiotic Kefir yogurt for combating pathogenic bacteria and treating various inflammatory conditions, including inflammatory bowel disease (IBD) and COVID-19 related cytokine storms.

12 Apr 2021

Researchers use genetics to identify potential drugs for early management of COVID-19

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

9 Apr 2021

Toward a transformative therapy for sickle cell patients

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms.

9 Apr 2021

Novel diarylamides show promise as orally active diuretics to treat hyponatremia

Urea transporters (UT) play a vital role in the mechanism of urine concentration and are recognized as novel targets for the development of salt-sparing diuretics. Thus, UT inhibitors are promising for development as novel diuretics.

8 Apr 2021

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has long studied neglected tropical diseases -- chronic and disabling parasitic infections that primarily affect poor and underserved communities in developing nations.

3 Apr 2021

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

A team of researchers has identified several candidates for drugs against the coronavirus SARS-CoV-2 at DESY´s high-brilliance X-ray lightsource PETRA III.

3 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

University of Birmingham researchers are working to isolate and extract the COVID-19 encounter complex in a form that is stable enough for identification of target sites for future anti-viral drugs.

27 Mar 2021

A novel approach to oral vaccination against Covid-19

Scientists at the University of Würzburg together with a pharmaceutical company are working on a novel approach to oral vaccination against the coronavirus.

26 Mar 2021

Drug Discovery & Pharmaceuticals

Drug-discovery collaboration finds potential new antimalarial drug candidates

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

New machine learning method for designing more effective antibody drugs

Linkam FDCS196 stage used in research to develop a novel transdermal delivery system for risperidone

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Natural treatment based on flour made from mealworms can help prevent Type II diabetes mellitus

MagnaPharm project opens up new possibilities in drug production

BGU researchers identify probiotic yogurt-based drug candidates

Researchers use genetics to identify potential drugs for early management of COVID-19

Toward a transformative therapy for sickle cell patients

Novel diarylamides show promise as orally active diuretics to treat hyponatremia

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

Scientists identify nine potential new COVID-19 treatments

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

A novel approach to oral vaccination against Covid-19

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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