Drug Discovery & Pharmaceuticals

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Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Sphere Fluidics 22 Apr 2020

New database of 14,000 known macrolactones could support drug discovery and research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

USPTO grants patent to TAU scientist for innovative coronavirus vaccine design

Researchers worldwide are racing at breakneck speed to develop potential vaccines and drugs to fight the novel coronavirus, SARS-Cov-2.

21 Apr 2020

Psychedelics can be produced in yeast

Psilocybin mushrooms have been found to have minimal harmful effects and could potentially benefit those with depression.

16 Apr 2020

Skoltech scientists propose new method to make doping tests quicker

Skoltech scientists and their colleagues proposed a way to simplify the search for traces of medicines, narcotic substances and sports doping drugs in human biological samples by performing two additional tests with the search domain reduced tenfold.

13 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

Chemists identify a drug to rescue winter depression-like behavior

A group of animal biologists and chemists at the Institute of Transformative Bio-Molecules, Nagoya University, has used a chemical genomics approach to explore the underlying mechanism of winter depression-like behavior and identified a drug that rescues winter depression-like behavior in medaka fish.

13 Apr 2020

Hinge Therapeutics and TUT collaborate to advance drug discovery by ion imaging

Hinge Therapeutics is an early-stage biopharmaceutical company focused on developing small-molecule therapeutics against traditionally undruggable/challenging targets for unmet medical needs.

9 Apr 2020

IRB Barcelona and Amazon join forces to develop computational tool in the fight against COVID-19

There are currently more than 10,000 scientific articles related to coronavirus infections. In fact, in recent weeks, research to combat COVID-19 has accelerated, and more than 4,000 new academic papers have been published on potential vaccines, therapies, and treatments.

3 Apr 2020

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

Cobra Biologics, an international CDMO for biologics and pharmaceuticals, and the Karolinska Institutet, one of the world’s leading medical universities, today announced they have been awarded €3 million emergency funding by Horizon 2020 for research and development, and phase I clinical trial testing of a DNA vaccine against COVID-19, as part of the OPENCORONA consortium to support global efforts tackling the pandemic.

31 Mar 2020

DSI alumni use computational design to quickly discover treatments for COVID-19

Two graduates of the Data Science Institute at Columbia University are using computational design to quickly discover treatments for the coronavirus.

21 Mar 2020

Researchers decode 3D architecture of SARS-CoV-2 main protease

Teams around the world are working hard to develop active substances against SARS-CoV-2. The structural analysis of functional proteins of the virus is very helpful for this goal. The function of a protein is closely related to its 3D architecture.

21 Mar 2020

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea, a sexually transmitted disease caused by bacteria that have developed resistance to all but one existing antibiotic.

20 Mar 2020

Scientists develop single-step method to produce water-soluble fullerene compounds for medicine

Scientists from the Skoltech Center for Energy Science and Technology and the Institute for Problems of Chemical Physics of Russian Academy of Sciences in collaboration with researchers from the Catholic University of Leuven developed a single-step method to obtain water-soluble fullerene compounds with remarkable biological properties, such as the ability to effectively suppress the human immunodeficiency virus

17 Mar 2020

Beijing Tide Pharmaceutical and Insilico Medicine announce cancer drug discovery collaboration

Beijing Tide Pharmaceutical Co., Ltd., a subsidiary of Sino Biopharmaceutical Limited, and Insilico Medicine, an artificial intelligence company developing end-to-end drug discovery pipelines, announced today that they are entering a collaboration, applying artificial intelligence technology to drug discovery, to jointly accelerate the process for multiple types of cancer treatment.

16 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

'Virtual screening' identifies active substances with potential to combat coronavirus

The University of Basel is part of the global search for a drug to fight the rampant coronavirus. Researchers in the Computational Pharmacy group have so far virtually tested almost 700 million substances, targeting a specific site on the virus - with the aim of inhibiting its multiplication.

11 Mar 2020

Drug Discovery & Pharmaceuticals

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

New database of 14,000 known macrolactones could support drug discovery and research

USPTO grants patent to TAU scientist for innovative coronavirus vaccine design

Psychedelics can be produced in yeast

Skoltech scientists propose new method to make doping tests quicker

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

Chemists identify a drug to rescue winter depression-like behavior

Hinge Therapeutics and TUT collaborate to advance drug discovery by ion imaging

IRB Barcelona and Amazon join forces to develop computational tool in the fight against COVID-19

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

DSI alumni use computational design to quickly discover treatments for COVID-19

Researchers decode 3D architecture of SARS-CoV-2 main protease

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Scientists develop single-step method to produce water-soluble fullerene compounds for medicine

Beijing Tide Pharmaceutical and Insilico Medicine announce cancer drug discovery collaboration

Single-drug therapy can attack several cellular targets using different modes of action

'Virtual screening' identifies active substances with potential to combat coronavirus

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

New route for total synthesis of tetrodotoxin

SFU researchers help discover potential new drug to kill superbugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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