Drug Discovery & Pharmaceuticals

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CRISPR may explain why so many experimental cancer drugs fail

Scientists have used CRISPR–Cas9 to investigate how ten cancer drugs interact with their protein target, revealing some intriguing findings.

13 Sep 2019

Researchers develop more efficient method to produce building blocks needed for drugs

Researchers at Tokyo University of Agriculture and Technology in Japan and Mount Allison University in Canada have developed a more efficient method to produce the building blocks needed for antibiotics and cancer treatment drugs.

12 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Discngine, a software company specialized in developing applications for life sciences research, today announces that Lundbeck has selected its proprietary 3decision collaborative platform to manage the pharma company’s structural knowledge related to protein and ligand 3D structures.

5 Sep 2019

Potential drug could revolutionize the treatment of neurological conditions

The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons.

28 Aug 2019

U of T scientists create antibodies with enormous potential for regenerative medicine

Our body makes antibodies to fight infections. But the synthetic versions of these molecules could hold the key to stimulating the body's ability to regenerate.

27 Aug 2019

Northern Antibiotics working on a new molecule to fight antibiotic-resistant bacteria

Each year, around 60,000 deaths are caused by antibiotic-resistant bacteria in Europe and the U.S., and this number is growing.

21 Aug 2019

Placing students at the heart of Albumedix

Albumedix employ two postgraduates through the University of Nottingham placements scheme with companies for 3-6 months for up to 200 hours.

From Albumedix Ltd. 20 Aug 2019

Albumedix ground-breaking ceremony

May 8th marked a big day in Albumedix’s history. Holding a traditional ground-breaking ceremony; our workforce, builders and contractors all gathered to watch Peter Rosholm (Chief Executive Officer) and Stuart Woodward (Chief Manufacturing Officer) take the first official step towards the company’s expansion.

From Albumedix Ltd. 20 Aug 2019

Albumedix announces evaluation agreement with a top pharma collaborator

Novartis and Albumedix Ltd. have entered into an agreement to evaluate the development of several first-in-class therapeutics using Albumedix’s Veltis technology platform and associated technologies.

From Albumedix Ltd. 20 Aug 2019

Discover the latest advances in neuromuscular therapeutics at NMD 2019

The 2nd Neuromuscular Drug Development Summit, or NMD, will be held in Boston, MA, from October 23-25,2019.

From Hanson Wade 19 Aug 2019

Ziath launches new YouTube channel to share its expertise with laboratories

Ziath is launching a new YouTube channel that will house informative videos previewing the latest innovations in the field of drug discovery and bio-banking sample management for the first time as the company seeks to share its expertise and knowledge with laboratories worldwide.

From Ziath Ltd 16 Aug 2019

Scientists take first step towards digital map of the ion channels in the brain

Researchers have mapped the molecular workings of voltage-gated potassium ion channels within the brain.

16 Aug 2019

Thermo Fisher Scientific unveils new Krios solution at Microscopy and Microanalysis 2019

Today at Microscopy and Microanalysis 2019, Thermo Fisher Scientific unveiled a new Krios solution designed to break down the barriers to cryo-EM adoption through improved ease-of-use, faster results and the most compact 300kV cryo-EM microscope design on the market.

From Thermo Fisher Scientific – Electron Microscopy Solutions 6 Aug 2019

Sanofi exercises option to advance innovative Bispecific Small Molecule project

Exscientia, the world-leading Artificial Intelligence (AI)-driven drug discovery company, today announced that Sanofi has exercised its option to progress an innovative Bispecific Small molecule project it discovered as part of its new modality collaboration.

From Sanofi 6 Aug 2019

New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria

Researchers have discovered a weak spot in the cell wall of pathogenic bacteria that could lead to the development of new antibiotics.

1 Aug 2019

Selective antibiotics could make precision treatment possible

With multi-resistant germs becoming more and more of a threat, we are in need of new antibiotics now more than ever.

31 Jul 2019

IONTAS and Teva Pharmaceuticals announce new antibody optimization agreement

IONTAS Limited, a leader in antibody discovery and optimization of human monoclonal antibody libraries, today announced an agreement with Teva Pharmaceuticals (Teva) to apply its technologies and know-how to the optimization of human antibodies for use as biotherapeutics.

From FairJourney Biologics 31 Jul 2019