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QUADRO trial demonstrates superior blood pressure control with four-in-one medication

A single-pill combination of four blood-pressure (BP)-lowering medications was significantly more effective than a combination of three medications, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Vutrisiran shows potential to become the new standard of care for rare heart disease

Vutrisiran significantly improved mortality, cardiovascular events and markers of disease progression in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Industrial biotech specialist Ingenza is delighted to announce that it is collaborating with Cellugy to accelerate the development of its innovative platform for producing biofabricated cellulose. This technology will provide a sustainable alternative to fossil-based petrochemicals in various industrial applications, starting with personal care. The new project will ultimately accelerate the understanding and optimization of bacterial cellulose production.

From Ingenza Ltd 30 Aug 2024

Ishani Malhotra named ‘woman entrepreneur of the year’ by cancer research horizons

Cancer Research Horizons, the innovation arm of Cancer Research UK, announced the winners of its second Innovation & Entrepreneurship Awards at it’s gala dinner on the 20th of March in London.These awards celebrate the UK’s most innovative and enterprising efforts in oncology highlighting those individuals in the industry working hard to translate discoveries into benefits for cancer patients.

From Carcinotech 30 Aug 2024

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

Advances in tissue engineering and 3D bioprinting have revolutionized the development of physiologically relevant 3D in vitro cancer models, offering a closer representation of the tumor microenvironment (TME) and enabling high-throughput drug screening.

From Carcinotech 30 Aug 2024

AmelHap: A honeybee haplotype map

Beebytes is very happy to have achieved its first publication, the development of a ‘HapMap’ for honey bees, in collaboration with the Roslin Institute, the University of the Basque Country in Spain, and the National Research Institute for Agriculture, Food and the Environment (INRAE) in France.

From Beebytes Analytics 30 Aug 2024

Probenecid shows promise for easing opioid withdrawal symptoms in new study

A deeper understanding of the communication inside the body when someone is going through opioid withdrawal has led to a new clinical trial at the University of Calgary.

29 Aug 2024

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Researchers used real-world clinical data to attempt to emulate a randomized controlled trial testing the effectiveness of two blood thinners, apixaban and warfarin, to prevent stroke in patients with non-valvular atrial fibrillation.

29 Aug 2024

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

Pregnant people who took the first dose of misoprostol (a pill given as part of the procedure for medical abortions) at home had a 71% chance of completing their care in hospital within 9 hours with no overnight stay when having an abortion after 12 weeks of pregnancy, compared to 46% of those who took the first dose of misoprostol at hospital, finds a randomized controlled trial published in The Lancet.

29 Aug 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

Investigational drug reduces hot flashes associated with menopause

The investigational drug elinzanetant significantly reduces the frequency and severity of hot flashes associated with menopause while improving women's quality of life, new UVA Health research published in the prestigious Journal of the American Medical Association shows.

22 Aug 2024

Belzutifan shows promise in treating advanced renal cell carcinoma

The LITESPARK-005 phase 3 clinical enrolled 746 patients with metastatic clear cell renal cell carcinoma (ccRCC) who had progressed after treatment with both an immune checkpoint inhibitor (ICI) and an anti-angiogenic therapy.

21 Aug 2024

Tecovirimat shows no significant impact on mpox lesion duration in DRC study

The antiviral drug tecovirimat did not reduce the duration of mpox lesions among children and adults with clade I mpox in the Democratic Republic of the Congo (DRC), based on an initial analysis of data from a randomized, placebo-controlled trial.

16 Aug 2024

Breakthrough malaria vaccine offers long-term protection for pregnant women

In a report published in The Lancet Infectious Diseases (Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomized, double-blind, placebo-controlled, phase 1 and 2 trials) a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable protective efficacy against malaria shown by Sanaria® PfSPZ Vaccine when administered to women prior to pregnancy.

14 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

Experimental malaria vaccine shows promise in protecting pregnant women

Two National Institutes of Health (NIH)-supported trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe.

14 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

Investigational drug shows promise in treating rare blood disease in fetuses

Data from a new investigational drug that could alter the standard treatment for a rare blood disease suggests it has the potential to delay or prevent anemia and the need for intrauterine blood transfusions in babies who are at high risk for the condition, known as Hemolytic Disease of the Fetus and Newborn (HDFN).

7 Aug 2024

New stem cell therapy for heart failure undergoing U.S. clinical trials

A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health.

7 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

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Drug Trial News

QUADRO trial demonstrates superior blood pressure control with four-in-one medication

Vutrisiran shows potential to become the new standard of care for rare heart disease

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Ishani Malhotra named ‘woman entrepreneur of the year’ by cancer research horizons

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

AmelHap: A honeybee haplotype map

Probenecid shows promise for easing opioid withdrawal symptoms in new study

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

TCT 2024 to feature latest advances in interventional cardiovascular medicine

Investigational drug reduces hot flashes associated with menopause

Belzutifan shows promise in treating advanced renal cell carcinoma

Tecovirimat shows no significant impact on mpox lesion duration in DRC study

Breakthrough malaria vaccine offers long-term protection for pregnant women

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Experimental malaria vaccine shows promise in protecting pregnant women

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

Investigational drug shows promise in treating rare blood disease in fetuses

New stem cell therapy for heart failure undergoing U.S. clinical trials

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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