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Gout medication reduces major cardiovascular events in heart patients

Colchicine reduces the risk of major cardiovascular events in patients with chronic coronary disease, according to results of the LoDoCo2 trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy, according to results of the EAST-AFNET 4 trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Study: Mavacamten improves heart function in patients with hypertrophic cardiomyopathy

Mavacamten improves heart function and symptoms in patients with obstructive hypertrophic cardiomyopathy, according to results of the EXPLORER-HCM trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Study shows best antiplatelet treatment after transcatheter aortic valve implantation

The POPular TAVI trial has challenged current guideline recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. The findings are presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

DAPA-CKD trial shows dapagliflozin reduces risk of chronic kidney disease

Dapagliflozin reduces the risk of kidney failure, death from cardiovascular causes or heart failure hospitalization and all-cause mortality in chronic kidney disease patients with or without type 2 diabetes.

31 Aug 2020

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

New breast cancer drug is safe and effective, can halt disease progression

A new type of breast cancer drug developed by researchers at the University of Illinois Chicago can help halt progression of disease and is not toxic, according to phase 1 clinical trials. The drug is specifically designed for women whose cancer has stopped responding to hormone therapy.

28 Aug 2020

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

A Cambridge-developed DNA vaccine candidate against SARS-CoV-2 could begin clinical trials in the UK in late autumn or early next year, thanks to a £1.9 million award from the UK government.

27 Aug 2020

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

The COVID-19 pandemic is still creating economic and health-related impact over the world. A new study published on the preprint server bioRxiv in August 2020 shows that a gp96-Ig-secreting vaccine candidate based on the expression of full-length spike protein generates a potent T cell response.

26 Aug 2020

LA hospital seeks vaccine trial participants among its own high-risk patients

The patients at Dr. Eric Daar's hospital are at high risk for serious illness from COVID-19, and he's determined to make sure they're part of the effort to fight the disease.

26 Aug 2020

Personalized genetic testing helps reduce adverse events following balloon angioplasty

An international, first-of-its-kind cardiology trial used personalized genetic testing to reduce by 34 per cent the number of serious adverse events following balloon angioplasty, a treatment for the most common form of heart disease.

26 Aug 2020

Vitamin D supplements do not prevent severe asthma attacks in children

Contrary to earlier results, vitamin D supplements do not prevent severe asthma attacks in at-risk children, according to the first placebo-controlled clinical trial to test this relationship.

25 Aug 2020

Italy starts human trials of potential COVID-19 vaccine

Rome's Lazzaro Spallanzani Institute, a hospital specializing in infectious diseases will conduct trials on 90 volunteers in the coming weeks, joining a global effort to develop an immune response to the virus.

25 Aug 2020

UH to participate as study site for Pfizer and BioNTech's COVID-19 vaccine

University Hospitals announced today plans to participate as a study site for the Phase 2/3 global study sponsored by Pfizer Inc. and BioNTech SE of an investigational vaccine, BNT162b2, against SARS-CoV-2.

24 Aug 2020

Evaluating the use of sofosbuvir and daclatasvir for treatment of COVID-19

Several new papers in Journal of Antimicrobial Chemotherapy, published by Oxford University Press, suggest successful treatments for COVID-19.

24 Aug 2020

New cancer vaccine is predicted to be more effective in human trials

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

24 Aug 2020

Combination therapy effective for patients with cholangiocarcinoma marked by BRAF mutations

In a Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, the combination of dabrafenib, a BRAF inhibitor, and trametinib, a MEK inhibitor, achieved a 51% overall response rate (ORR) in patients with cholangiocarcinoma marked by the BRAF V600E mutation.

18 Aug 2020

Wits University begins South African trial of Novavax COVID-19 vaccine

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Drug Trial News

Gout medication reduces major cardiovascular events in heart patients

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy

Study: Mavacamten improves heart function in patients with hypertrophic cardiomyopathy

Study shows best antiplatelet treatment after transcatheter aortic valve implantation

DAPA-CKD trial shows dapagliflozin reduces risk of chronic kidney disease

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

New breast cancer drug is safe and effective, can halt disease progression

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

LA hospital seeks vaccine trial participants among its own high-risk patients

Personalized genetic testing helps reduce adverse events following balloon angioplasty

Vitamin D supplements do not prevent severe asthma attacks in children

Italy starts human trials of potential COVID-19 vaccine

UH to participate as study site for Pfizer and BioNTech's COVID-19 vaccine

Evaluating the use of sofosbuvir and daclatasvir for treatment of COVID-19

New cancer vaccine is predicted to be more effective in human trials

Combination therapy effective for patients with cholangiocarcinoma marked by BRAF mutations

Wits University begins South African trial of Novavax COVID-19 vaccine

With COVID vaccine trial, rural Oregon clinic steps onto world stage

PARP inhibitor can successfully treat a subset of advanced prostate cancer patients

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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