Genomics

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Researchers identify new gene variants that may cause inherited retinal dystrophies

An international team of researchers, led by scientists at University of California San Diego and Shiley Eye Institute at UC San Diego Health, has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

20 Oct 2021

New technology streamlines the development of gene therapy for genetic blinding disorders

A novel computational platform developed by researchers from the University of Pittsburgh School of Medicine identifies top-performing viral vectors that could deliver gene therapies to the retina with maximum efficiency and precision.

19 Oct 2021

Study may help investigate the role of gut virome in health and disease

A new study has added numerous previously uncharacterized viral genomes and genes to the ever-increasing worldwide pool of human gut viromes.

19 Oct 2021

Researchers identify the genetic changes responsible for drug resistance in tuberculosis

Using cutting-edge genomic sequencing techniques, researchers at the University of Oxford have identified almost all the genomic variation that gives people resistance to 13 of the most common tuberculosis (TB) drug treatments.

19 Oct 2021

Study highlights the critical role of junk DNA in mammalian development

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Researchers reveal the mechanism of artificial chromosome formation in C. elegans' embryos

A research team led by Dr Karen Wing Yee YUEN, Associate Professor from the School of Biological Sciences at the University of Hong Kong (HKU), revealed the mechanism of artificial chromosome (AC) formation in the embryos of the model organism Caenorhabditis elegans, a 1-mm long, transparent nematode.

18 Oct 2021

Two defense systems in bacteria work in a complementary manner to protect from viruses

A new study led by a team of bioscientists from Durham University, UK, in collaboration with University of Liverpool, Northumbria University and New England Biolabs, hopes to exploit newly characterized defense systems in bacteria to compare changes to the human genome.

18 Oct 2021

Three new genetic variants linked to fibromuscular dysplasia

Three new genetic variants that regulate gene expression in the arteries are connected to fibromuscular dysplasia, an arterial disease that can cause dangerous consequences for the heart and vessels, according to a new study.

18 Oct 2021

UC Davis researchers publish the first atlas of metabolites in the mouse brain

The first atlas of metabolites in the mouse brain has been published by a team led by UC Davis researchers.

18 Oct 2021

Study provides the most detailed analysis of England's SARS-CoV-2 genomic surveillance information

The Covid-19 crisis that gripped the UK between September 2020 and June 2021 can be thought of as a series of overlapping epidemics, rather than a single event, say researchers at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and their collaborators.

18 Oct 2021

AI-based technology rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego.

15 Oct 2021

Novel method for rapid incidence estimation from SARS-CoV-2 genomes

Daily counts of new COVID-19 cases remain a basis for evaluating the state of the pandemic and are vital for making informed decisions on public interventions.

15 Oct 2021

AI algorithm accurately detects disease-causing variants in infants with rare diseases

Fabric Genomics and Rady Children's Institute for Genomic Medicine today announced the publication of a retrospective study in Genome Medicine showing that across six leading genomic centers and hospitals, researchers were able to detect more than 90% of disease-causing variants in infants with rare diseases using the Fabric GEM AI algorithm and whole-genome and whole-exome data from previously diagnosed newborns and rare disease patients at Rady Children's Hospital - San Diego and other clinical sites.

15 Oct 2021

Mapping proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council Epidemiology Unit at the University of Cambridge, challenging the categorization of diseases by organ, symptoms, or clinical specialty.

15 Oct 2021

Genes play a significant role in how the body responds to exercise, finds study

A new study has found that genes play a significant role in how our bodies respond to exercise and has identified a number of specific genes that influence the outcomes of different kinds of physical activity.

15 Oct 2021

Qatar genomics study reveals key historical and social insights into Arab populations

Researchers in Qatar have unveiled a high-resolution map of the genetic structure of Arab and Middle Eastern populations, providing new insights into human history in the region and ancestral patterns that may help to explain local human traits and disease risks.

15 Oct 2021

Genome of obese Ossabaw pig could provide new insights into human obesity

Mapping of the complete genome of the obesity-prone Ossabaw pig gives new hope for further insights into human obesity and associated diseases.

14 Oct 2021

Study identifies DNA mutations linking liver disease with obesity and diabetes

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

13 Oct 2021

Study identifies a new detrimental effect of genes that cause inherited diseases

Scientists have identified a new detrimental effect of genes that cause inherited diseases, publishing their results today in eLife.

12 Oct 2021

A new technique for long-term preservation of fruit fly populations

The fruit fly Drosophila melanogaster has long been an important experimental model for biological research. While you may be eager to rid your kitchen of this unwanted pest, researchers in Japan have developed a new technique to keep Drosophila in the laboratory even longer.

12 Oct 2021

Genomics

Researchers identify new gene variants that may cause inherited retinal dystrophies

New technology streamlines the development of gene therapy for genetic blinding disorders

Study may help investigate the role of gut virome in health and disease

Researchers identify the genetic changes responsible for drug resistance in tuberculosis

Study highlights the critical role of junk DNA in mammalian development

Researchers reveal the mechanism of artificial chromosome formation in C. elegans' embryos

Two defense systems in bacteria work in a complementary manner to protect from viruses

Three new genetic variants linked to fibromuscular dysplasia

UC Davis researchers publish the first atlas of metabolites in the mouse brain

Study provides the most detailed analysis of England's SARS-CoV-2 genomic surveillance information

AI-based technology rapidly identifies genetic causes of rare disorders with high accuracy

Novel method for rapid incidence estimation from SARS-CoV-2 genomes

AI algorithm accurately detects disease-causing variants in infants with rare diseases

Mapping proteo-genomic connections between different human diseases

Genes play a significant role in how the body responds to exercise, finds study

Qatar genomics study reveals key historical and social insights into Arab populations

Genome of obese Ossabaw pig could provide new insights into human obesity

Study identifies DNA mutations linking liver disease with obesity and diabetes

Study identifies a new detrimental effect of genes that cause inherited diseases

A new technique for long-term preservation of fruit fly populations

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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