Genomics

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Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

24 Jun 2020

Researchers develop eDNA method to prevent emergence of pathogens

As the SARS-CoV-2 puts a new focus on zoonotic pathogens, a Washington State University researcher has developed a method to use environmental DNA (eDNA) to detect disease in the vast international trade of aquatic animals.

24 Jun 2020

New technique helps measure dNTP concentrations with greater sensitivity

A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer.

24 Jun 2020

Researchers develop less invasive genetic tools to understand cellular activity

Graduate student Ubadah Sabbagh placed a cold glass slide on the microscope. It was getting late and the lab was quiet.

24 Jun 2020

Long-term endurance training alters the activity of genes involved in metabolic health

Decades-long endurance training alters the activity of genes in human skeletal muscle that are important for metabolic health.

23 Jun 2020

Researchers identify genes that determine the optimal time of flowering

How do plants know when it is time to flower? Researchers at Martin Luther University Halle-Wittenberg (MLU) have studied this question and identified two genes that are key to this process.

23 Jun 2020

Patient genetics associated with wound microbiome composition and healing

In a first-of-its-kind study, researchers have determined that genetics may play a role in how wounds heal.

22 Jun 2020

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict the remaining lifespan in both sexes and the remaining years of fertility in women, according to the University of Utah Health scientists.

19 Jun 2020

Viruses can steal genetic signals from hosts to expand their own genomes

Like a scene out of "Invasion of the Body Snatchers," a virus infects a host and converts it into a factory for making more copies of itself.

19 Jun 2020

Using stem cells to study the developmental effects of Neandertal DNA

Protocols that allow the transformation of human induced pluripotent stem cell (iPSC) lines into organoids have changed the way scientists can study developmental processes and enable them to decipher the interplay between genes and tissue formation, particularly for organs where primary tissue is not available.

18 Jun 2020

Coastal Genomics automates DNA purification process using 3D printing – accelerating cancer research, prenatal screening and numerous other fields by partnering with Sculpteo

Coastal Genomics, experts in life sciences automation, selected Sculpteo, a leader in online 3D printing and digital manufacturing, to develop unique components for an automated DNA purification process.

18 Jun 2020

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

Researchers analyze immune properties of ancient human DNA

Could remnants of DNA from a now-extinct human subspecies known as the Denisovans help boost the immune functions of modern humans?

16 Jun 2020

Study aims to identify key genes involved in the body's response to COVID-19 infection

Data from popular home genetic-testing kits could help scientists shed light on why some people who catch coronavirus have no symptoms while others become very ill.

15 Jun 2020

Study: Parasite infection closely linked to the make-up of gastrointestinal microbiome

Parasite infections are a constant presence for many people who live in tropical regions, particularly in less industrialized areas.

14 Jun 2020

Genomic analysis of medieval skeletons has important implications for syphilis history in Europe

Mass burials are common remnants of the many plague outbreaks that ravaged Medieval Europe. A number of these graveyards are well documented in historical sources, but the locations of most, and the victims they contain, have been lost to the pages of time. In Vilnius, Lithuania, one such cemetery was found in a typical way: accidental discovery during a routine city construction project.

12 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Study identifies potential high-risk virulent clones circulating in European hospitals

UAB researchers, based on a collection of clinical isolates from several countries, have established a link between the cell-to-cell communication system (the quorum sensing) and the virulence and resistance phenotypes in Stenotrophomonas maltophilia.

10 Jun 2020

Plasmodium parasites have timekeeping systems that maintain their cell cycle activities

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

Study provides molecular explanation to a longstanding mystery in viral oncology

The oncogenic herpesvirus (HHV8 or KSHV) causes a cancer known as Kaposi's Sarcoma. An international team of scientists led by the University of Helsinki has discovered key factors that control the genome maintenance and replication of a virus responsible for lymphatic vascular cancer.

10 Jun 2020

Genomics

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

Researchers develop eDNA method to prevent emergence of pathogens

New technique helps measure dNTP concentrations with greater sensitivity

Researchers develop less invasive genetic tools to understand cellular activity

Long-term endurance training alters the activity of genes involved in metabolic health

Researchers identify genes that determine the optimal time of flowering

Patient genetics associated with wound microbiome composition and healing

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Viruses can steal genetic signals from hosts to expand their own genomes

Using stem cells to study the developmental effects of Neandertal DNA

Coastal Genomics automates DNA purification process using 3D printing – accelerating cancer research, prenatal screening and numerous other fields by partnering with Sculpteo

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

Researchers analyze immune properties of ancient human DNA

Study aims to identify key genes involved in the body's response to COVID-19 infection

Study: Parasite infection closely linked to the make-up of gastrointestinal microbiome

Genomic analysis of medieval skeletons has important implications for syphilis history in Europe

Study provides new evidence that liver dysfunction may lead to heart disease

Study identifies potential high-risk virulent clones circulating in European hospitals

Plasmodium parasites have timekeeping systems that maintain their cell cycle activities

Study provides molecular explanation to a longstanding mystery in viral oncology

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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