Genomics

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Study identifies more than 6,000 antibiotic resistance genes found in gut bacteria

A study carried out in collaboration with the University of Birmingham has used an innovative approach to identify thousands of antibiotic resistance genes found in bacteria that inhabit the human gut.

3 Dec 2018

Light-activated tools allow scientists to accurately probe intracellular phase separation

Creating new tools that harness light to probe the mysteries of cellular behavior, Princeton researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells.

30 Nov 2018

New study could fine-tune the CRISPR gene editing process

The introduction of the tool for gene editing, the so-called gene scissors CRISPR, in 2007 was a revolution within medical science and cell biology.

30 Nov 2018

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

From January 1, 2019, the German Research Foundation will be funding the new Collaborative Research Center 1361 on Regulation of DNA Repair & Genome Stability.

29 Nov 2018

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

The New York Genome Center has received approval from the New York State Department of Health to offer whole genome and RNA transcriptome sequencing in its Clinical Laboratory Evaluation Program-certified laboratory.

29 Nov 2018

Discovery about DNA twists could be crucial in development of new antibiotics

DNA replication is vital to all lifeforms, but in some organisms, it can be prevented by twists in the DNA sequence, called 'supercoils'. If too many supercoils are allowed to build up, cells vital to sustaining life will die.

28 Nov 2018

Researchers map cells in the early human placenta to shed light on pregnancy complications

To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to date has focused on those later stages of pregnancy. But the biological events that lead to these problems could start much earlier.

28 Nov 2018

Novel methodology for characterizing neurons could lead to better understanding of brain disease

It takes a lot of cells to make a human brain. The organ houses not only an enormous quantity of neurons (tens of billions), but also an impressive diversity of neuron types. In recent years, scientists have been developing inventories of these cell classes--information that will be essential for understanding how the brain works.

28 Nov 2018

New platform for metagenomic analysis

A team of developers from Skolkovo, ITMO University and MIPT presented an online service called Knomics-Biota, which allows for a comprehensive study of intestinal microbiome genetic data.

27 Nov 2018

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Given this morning's reports of infants possibly born in China whose genomes were edited by CRISPR-based technology, the American Society of Human Genetics (ASHG) reaffirms the cautious but proactive approach recommended in its 2017 position statement on human germline genome editing, published in The American Journal of Human Genetics.

26 Nov 2018

International study of ADHD at genomic scale

An international study, focused on the analysis of the genome of more than 50,000 people worldwide, has identified twelve specific fragments of DNA related to the vulnerability of the attention deficit hyperactivity disorder.

26 Nov 2018

Study finds genetic links between alcohol dependence and psychiatric disorders

In the largest study of genetic factors linked to alcohol dependence, an international team of researchers identified a gene known to affect risk, and they determined that many other genes also contribute to risk for alcohol dependence to a lesser degree.

26 Nov 2018

Researchers attempt to create world's first genetically edited babies

The researchers have used CRISPR to edit the genes of IVF embryos in a controversial attempt to create offspring that are resistant to disease.

26 Nov 2018

New method enhances efficiency and accuracy of single cell RNA sequencing

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.

22 Nov 2018

Scientists uncover genomic keys to successful evolution of vertebrates

One of the most important results of this work consists of understanding how the genomic duplications that occurred in the origin of the vertebrates contributed to diversifying gene function.

22 Nov 2018

Scientists identify three genes responsible for recurrent molar pregnancies

A team of scientists at the Research Institute of the McGill University Health Centre and McGill University have identified three genes responsible for recurrent molar pregnancies, a rare complication that occurs when a non-viable pregnancy with no embryo implants in the uterus.

20 Nov 2018

Researchers shed light on molecular mechanisms of heart valvular disease

About three per cent of the world's population is affected by valvular heart diseases. It is also the most common cause of heart surgery, as no drug-based treatment is available.

20 Nov 2018

Special care should be taken with drugs that inhibit epigenetic factors, study suggests

A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.

20 Nov 2018

Scientists uncover unexpected 'foreign' genes in tiny itch-inducing chigger mite

Scientists at the University of Liverpool have uncovered some unexpected 'foreign' genes in the tiny itch-inducing chigger mite and its more benign but enormous cousin, the giant velvet mite.

20 Nov 2018

About 300 million bits of DNA are missing from basic reference genome, report scientists

For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of "baseline" reference and human species representation for comparing genetic variety among groups of people.

20 Nov 2018

Genomics

Study identifies more than 6,000 antibiotic resistance genes found in gut bacteria

Light-activated tools allow scientists to accurately probe intracellular phase separation

New study could fine-tune the CRISPR gene editing process

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

Discovery about DNA twists could be crucial in development of new antibiotics

Researchers map cells in the early human placenta to shed light on pregnancy complications

Novel methodology for characterizing neurons could lead to better understanding of brain disease

New platform for metagenomic analysis

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

International study of ADHD at genomic scale

Study finds genetic links between alcohol dependence and psychiatric disorders

Researchers attempt to create world's first genetically edited babies

New method enhances efficiency and accuracy of single cell RNA sequencing

Scientists uncover genomic keys to successful evolution of vertebrates

Scientists identify three genes responsible for recurrent molar pregnancies

Researchers shed light on molecular mechanisms of heart valvular disease

Special care should be taken with drugs that inhibit epigenetic factors, study suggests

Scientists uncover unexpected 'foreign' genes in tiny itch-inducing chigger mite

About 300 million bits of DNA are missing from basic reference genome, report scientists

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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