Genomics

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Specific class of biomarkers can accurately indicate the severity of cancer

A cancer diagnosis tells you that you have cancer, but how that cancer will progress is a terrifying uncertainty for most patients. Researchers at Cold Spring Harbor Laboratory have now identified a specific class of biomarkers that can tell a lot about how aggressive a patient's cancer will be.

11 Dec 2018

Research pinpoints two proteins involved in creation of stem cells

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

11 Dec 2018

Lifespan extension at low temperatures depends on individual's genes, study shows

Why do we age? Despite more than a century of research (and a vast industry of youth-promising products), what causes our cells and organs to deteriorate with age is still unknown.

11 Dec 2018

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers from the Spanish Research Council at the Centre for Research in Agricultural Genomics and the Institute for Plant Molecular and Cellular Biology, in collaboration with the IATA, have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in plants.

10 Dec 2018

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

Cancer Research UK and AstraZeneca have announced today (Monday) that they are opening a new center in the UK, dedicated to realizing the full potential of functional genomics in the discovery and development of new drugs for patients with cancer.

10 Dec 2018

New way to trace the transmission histories of rare genetic diseases

There are only 25 people in the whole of Quebec at the moment who have a rare recessive genetic disease called chronic atrial and intestinal dysrhythmia. Now, scientists have begun tracing the origins of these diseases.

6 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

Jawless fish study provides a new story for inner ear evolution

Researchers at the RIKEN Center for Biosystems Dynamics (BDR) and collaborators have described for the first time the development of the hagfish inner ear. Published in the journal Nature, the study provides a new story for inner ear evolution that began with the last common ancestor of modern vertebrates.

6 Dec 2018

New massive sequencing platform implemented for double factor preimplantation genetic testing

A research team from the Universitat Autònoma de Barcelona, in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Preimplantation Genetic Testing for the first time in history.

5 Dec 2018

Scientists reveal how DNA damage leads to cancer and hereditary diseases

Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by errors in DNA doubling, but by damage to this fragile molecule.

5 Dec 2018

Researchers find evidence of epigenetics in single-celled archaea

Researchers have found evidence of epigenetics-based evolution in a species of archaea, our oldest single-cell ancestors.

5 Dec 2018

Researchers take a step forward with a study of molecules of DNA

Researchers from the Andalusian center for Molecular Biology and regenerative Medicine and from the University of Seville have taken a step forward with a study of something as essential for life as the molecules of DNA.

5 Dec 2018

Ethnicity can be reliable indicator of gut microbiota diversity

Research increasingly links the gut microbiome to a range of human maladies, including inflammatory bowel disease, diabetes and even cancer. Attempts to manipulate the gut with food rich in healthy bacteria, such as yogurt or kombucha, are in vogue, along with buying commercial probiotics that promise to improve users' chances against illness.

4 Dec 2018

Selective survival of embryos under adverse conditions may explain health problems later in life

An international team led by researchers of the Leiden University Medical Center and Lund University in Sweden propose that selection of random epigenetic differences causes particular embryos to survive under adverse conditions in the womb.

4 Dec 2018

Cancer DNA signature will revolutionize point-of-care diagnostics

Researchers have developed a potentially game-changing new technology that could revolutionize cancer point-of-care (POC) diagnostics.

4 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

Study provides new insights into mechanisms used by cells to transmit genetic information

The integrity of the genome relies on the ability of the cells to build and maintain a well-defined boundary between the nuclear compartment and the cytoplasm, known as the nuclear envelope.

4 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Epigenetic maps of the inner ear could lead to development of therapeutics for hearing loss

Epigenetics is the expression and control of genes. The epigenetics involved in the inner ear is a critical part of the mystery of hearing.

3 Dec 2018

Genomics

Specific class of biomarkers can accurately indicate the severity of cancer

Research pinpoints two proteins involved in creation of stem cells

Lifespan extension at low temperatures depends on individual's genes, study shows

Researchers develop biotechnological tool to produce antifungal proteins in plants

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

New way to trace the transmission histories of rare genetic diseases

Elevated hormone flags liver disease in mice with serious genomic disorder

Jawless fish study provides a new story for inner ear evolution

New massive sequencing platform implemented for double factor preimplantation genetic testing

Scientists reveal how DNA damage leads to cancer and hereditary diseases

Researchers find evidence of epigenetics in single-celled archaea

Researchers take a step forward with a study of molecules of DNA

Ethnicity can be reliable indicator of gut microbiota diversity

Selective survival of embryos under adverse conditions may explain health problems later in life

Cancer DNA signature will revolutionize point-of-care diagnostics

Researcher discovers key differences in protein production between healthy cells and tumors

Study provides new insights into mechanisms used by cells to transmit genetic information

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

Customizing Genetically Engineered Models for Specific Research Applications

Epigenetic maps of the inner ear could lead to development of therapeutics for hearing loss

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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