Genomics

RSS

CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

Scientists identify genetic risk factors underlying penicillin allergy

Penicillin, a life-saving medicine, is the most common cause of drug allergy, with clinical manifestations ranging from temporary skin reactions to life-threatening systemic syndromes.

3 Sep 2020

Researchers identify a pattern in cancer’s chromosomal chaos

Researchers at the Francis Crick Institute and the UCL Cancer Institute have identified how different cancers go through some of the same genetic mutations at the same point in their evolution.

3 Sep 2020

Researchers investigate persistence of reproductive cells despite damage from jumping genes

Believe it or not, your genes are 50% parasite, and opportunistic at that. They tend to jump onto sperm and egg cells to replicate in the next generation, a process that can devastate an egg or sperm cell.

1 Sep 2020

Previously overlooked insect shows promise as alternative protein source

With global food demands rising at an alarming rate, a study led by IUPUI scientists has found new evidence that a previously overlooked insect shows promise as alternative protein source: the yellow mealworm.

31 Aug 2020

DNA structure is determined by spatial rules based on specific protein sequences and their order

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order.

28 Aug 2020

Study can help improve rapeseed oil composition

A group of scientists from Skoltech and Pustovoit All-Russian Research Institute of Oil Crops in Krasnodar performed genetic analysis of the Russian rapeseed collection.

28 Aug 2020

Researchers discover genetic link between cattle temperament and autism in humans

A strong association between the genes influencing cattle temperament and autism in humans has been discovered by University of Queensland researchers.

27 Aug 2020

New sequencing approach can detect rare mutation in large number of cells

A sequencing approach can home in on a rare mutation within a large number of cells, revealing implications for CRISPR genome editing and early cancer detection.

27 Aug 2020

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

An international team of researchers has discovered a new group of Chlamydiae - Anoxychlamydiales - living under the ocean floor without oxygen.

27 Aug 2020

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

Humans are not the only species facing a potential threat from SARS-CoV-2, the novel coronavirus that causes COVID-19, according to a new study from the University of California, Davis.

21 Aug 2020

Study could help understand the evolution of nervous systems in animals and humans

When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals. But how did they get that way?

20 Aug 2020

Adaptions to aging may be impacted by genetic background

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

19 Aug 2020

Women's reproductive tract mediates post-mating sexual selection, shows study

The female reproductive tract has the final say in human mate choice, according to new research from the University of Eastern Finland.

19 Aug 2020

Standardized guidelines for phage therapy can speed up lifesaving treatment

When clinicians resort to phage therapy for patients who don't respond to antibiotics, the patients are usually very ill and time is of the essence. But the average time for labs to produce therapeutic phages is more than a month.

17 Aug 2020

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Bishop Peder Winstrup of Lund, Sweden passed away in the winter of 1679 at the age of 74 and was interred in a crypt at Lund Cathedral.

15 Aug 2020

Engineered capsids for improved gene delivery to the retina and cornea

A rational design approach created novel variants of adeno-associated viral (AAV) capsids.

13 Aug 2020

Europeans could have been infected with syphilis before Columbus set sails to America

Columbus brought syphilis to Europe – or did he? A recent study conducted at the University of Zurich now indicates that Europeans could already have been infected with this sexually transmitted disease before the 15th century.

13 Aug 2020

Genomics

CRISPR-based system suppresses genes related to AAV antibody production

Scientists identify genetic risk factors underlying penicillin allergy

Researchers identify a pattern in cancer’s chromosomal chaos

Researchers investigate persistence of reproductive cells despite damage from jumping genes

Previously overlooked insect shows promise as alternative protein source

DNA structure is determined by spatial rules based on specific protein sequences and their order

Study can help improve rapeseed oil composition

Researchers discover genetic link between cattle temperament and autism in humans

New sequencing approach can detect rare mutation in large number of cells

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

Advances in Virus Epigenetics

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

Study could help understand the evolution of nervous systems in animals and humans

Adaptions to aging may be impacted by genetic background

Women's reproductive tract mediates post-mating sexual selection, shows study

Standardized guidelines for phage therapy can speed up lifesaving treatment

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Engineered capsids for improved gene delivery to the retina and cornea

Europeans could have been infected with syphilis before Columbus set sails to America

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Latest Life Science News