Genomics

RSS

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Cytosurge AG, a company manufacturing unique high-precision nanotechnology instruments, announced that they will collaboratively investigate CRISPR-based approaches to more effectively introduce multiple edits into the genome of single cells, while minimizing CRISPR-related toxicity.

4 May 2020

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Researchers at EMBL's European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute analysed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

2 May 2020

Study explores molecular connections between genetics, gut microbiome and memory

A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population.

29 Apr 2020

Studies show how sex-determining genes affect courtship and aggression behaviors

Fruit flies, like many animals, engage in a variety of courtship and fighting behaviors. Now, Salk scientists have uncovered the molecular mechanisms by which two sex-determining genes affect fruit fly behavior.

28 Apr 2020

Father's Toxoplasma infection can impact their offspring's brain health and behavior

Australian researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior.

28 Apr 2020

Virus genomes help to explain why a major livestock disease has re-emerged in Europe

New research shows that the recent re-emergence of BTV in French livestock could have been caused by human activities.

28 Apr 2020

Scientists decode herpes simplex virus 1

Until now, scientists had assumed that there are about 80 so-called open reading frames (ORFs) in the genome of herpes simplex virus 1 (HSV-1).

27 Apr 2020

Microfluidic Systems for Sweat Analysis and Neonatal Care

This interview provides insight into microfluidic systems and devices and the role they are playing in sweat analysis and neonatal care.

From Pittcon 24 Apr 2020

New genome-editing techniques could make recombinant-protein drugs cheaper

The mammalian cell lines that are engineered to produce high-value recombinant-protein drugs also produce unwanted proteins that push up the overall cost to manufacture these drugs. These same proteins can also lower drug quality

24 Apr 2020

Bayreuth researchers discover natural protective mechanism against cancer

Susanne Hellmuth and Olaf Stemmann from the Chair of Genetics at the University of Bayreuth have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells.

23 Apr 2020

Researchers develop a faster visualization method for constructing pan-genome subgraphs

Kadir Dede and Dr. Enno Ohlebusch at Ulm University in Germany have devised a method for constructing pan-genome subgraphs at different granularities without having to wait hours and days on end for the software to process the entire genome.

23 Apr 2020

Research on sweet potato microbiome is a major step for enhancing yield

Grown around the world, sweet potatoes are an important source of nutrition particularly in sub-Saharan African and Asian diets. Sweet potatoes are especially significant to sub-Saharan Africa as a source of Vitamin A, a nutrient commonly deficient in the region.

23 Apr 2020