Genomics

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Study shows how 3D organization of genetic material helps perpetuate the species

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear.

19 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

IDT expands its courier zones in the UK

As an advocate for researchers in the genomics age, Integrated DNA Technologies (IDT) is expanding its courier zones to ensure that the highest-fidelity oligos are available in less time and at the same price, to more customers.

From Integrated DNA Technologies 15 Feb 2019

Scientists shed light on damaging cell effects linked to aging

Some of the damaging cell effects linked to aging could be prevented by manipulating tiny parts of cells, a study shows.

14 Feb 2019

Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Employing advanced genetic-tracing techniques and sharing the data produced in real time could limit the spread of bacteria -- Bacillus cereus -- which cause foodborne illness, according to researchers who implemented whole-genome sequencing of a pathogen-outbreak investigation.

14 Feb 2019

Study: Prime real estate is determined by previous owner in the squirrel world

A young squirrel lucky enough to take over territory from an adult male squirrel is like a teenager falling into a big inheritance, according to a new University of Guelph study.

14 Feb 2019

Researchers comprehensively sequence the human immune system

For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system -- the genes encoding the circulating B cell receptor repertoire.

14 Feb 2019

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer.

14 Feb 2019

Oxford Genetics appoints Jocelyne Bath as new Chief Operating Officer

Oxford Genetics, a leader in innovative synthetic biology-based technologies for biologics discovery, development and delivery, announces the appointment of their new Chief Operating Officer, Jocelyne Bath.

From OXGENE 13 Feb 2019

New process efficiently reprograms stem cells in one step using measles virus vector

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

13 Feb 2019

Microbiologists identify enzyme that makes Helicobacter so adaptable

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

13 Feb 2019

NIH scientists zero in on genes associated with AMD

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration, a leading cause of vision loss and blindness among people age 65 and older.

12 Feb 2019

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations.

12 Feb 2019

Scientists develop machine-learning approach to identify source of Salmonella

A team of scientists led by researchers at the University of Georgia Center for Food Safety in Griffin has developed a machine-learning approach that could lead to quicker identification of the animal source of certain Salmonella outbreaks.

12 Feb 2019

New model sheds light on how small cell lung cancer is initiated

Scientists from Weill Cornell Medicine have developed a stem-cell-based model of small cell lung cancer that will help them understand how the disease is initiated and how it progresses.

11 Feb 2019

Research sheds light on how motor enzyme can promote genome integrity

Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy.

11 Feb 2019

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent.

11 Feb 2019

When genomic sequencing fails to diagnose a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in the journal Molecular & Cellular Proteomics.

11 Feb 2019

Scientists develop novel way with genome sequences to study widespread form of malaria

Scientists at the Institute of Genome Sciences at the University of Maryland School of Medicine have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes.

11 Feb 2019

Genomics

Study shows how 3D organization of genetic material helps perpetuate the species

Researchers identify multiple genetic variants associated with body fat distribution

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

IDT expands its courier zones in the UK

Scientists shed light on damaging cell effects linked to aging

Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Study: Prime real estate is determined by previous owner in the squirrel world

Researchers comprehensively sequence the human immune system

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Oxford Genetics appoints Jocelyne Bath as new Chief Operating Officer

New process efficiently reprograms stem cells in one step using measles virus vector

Microbiologists identify enzyme that makes Helicobacter so adaptable

NIH scientists zero in on genes associated with AMD

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Scientists develop machine-learning approach to identify source of Salmonella

New model sheds light on how small cell lung cancer is initiated

Research sheds light on how motor enzyme can promote genome integrity

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

When genomic sequencing fails to diagnose a rare disease

Scientists develop novel way with genome sequences to study widespread form of malaria

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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